About 12,340 results

ALLMedicine™ Purpura Center

Research & Reviews  3,484 results

Self-limited thrombotic thrombocytopenic purpura.
Blood Coagulation & Fibrinolysis : an International Journ... Duerson WA, Lopes CE et. al.

Feb 3rd, 2023 - Our team is presenting a patient who is a 57-year -old woman with a past medical history of cerebral vascular accident. The patient presented to the emergency department with symptoms of fever, right upper quadrant pain, and emesis. Initial diagno...

Safety and efficacy of caplacizumab in a case of thrombotic thrombocytopenic purpura in...
Blood Coagulation & Fibrinolysis : an International Journ... Bruzzese A, Vigna E et. al.

Feb 3rd, 2023 - Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening disease for which pregnancy and the postpartum period represent risk factors. Here, we present the case of a 39-year-old woman at the 31st week of gestation, who presented wi...

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

Feb 1st, 2023 - Study duration per participant is approximately 2 months up to approximately 6 months in case of treatment extension and recurrence during the study drug treatment period.

Delayed normalisation of ADAMTS13 activity in acute Thrombotic Thrombocytopenic Purpura...
Blood Prasannan N, Thomas M et. al.

Feb 1st, 2023 - The benefits of caplacizumab in acute immune mediated TTP (iTTP) are well established. We identified a delay in normalisation of ADAMTS13 activity (>30%) in a subgroup of caplacizumab treated patients which was not evident in the pre-caplacizumab ...

Differences in IgG autoantibody Fab glycosylation across autoimmune diseases.
The Journal of Allergy and Clinical Immunology; Koers J, Sciarrillo R et. al.

Jan 31st, 2023 - Increased prevalence of autoantibody Fab glycosylation has been demonstrated for several autoimmune diseases. To study if elevated Fab glycosylation is a common feature of autoimmunity, we investigated Fab glycosylation levels on serum IgG and its...

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Guidelines  5 results

Oropharyngeal psychogenic purpura.
British Journal of Haematology; Allar BG, Michaelsen K et. al.

Aug 6th, 2020 - Oropharyngeal psychogenic purpura.|2020|Allar BG,Michaelsen K,Gupta A,Bose S,|metabolism,pathology,metabolism,pathology,metabolism,pathology,metabolism,pathology,metabolism,pathology,

European consensus-based recommendations for diagnosis and treatment of immunoglobulin ...
Rheumatology (Oxford, England); Ozen S, Marks SD et. al.

Mar 18th, 2019 - IgA vasculitis (IgAV, formerly known as Henoch-Schönlein purpura) is the most common cause of systemic vasculitis in childhood. To date, there are no internationally agreed, evidence-based guidelines concerning the appropriate diagnosis and treatm...

ACG Clinical Guideline: Treatment of Helicobacter pylori Infection.
The American Journal of Gastroenterology; Chey WD, Leontiadis GI et. al.

Jan 11th, 2017 - Helicobacter pylori (H. pylori) infection is a common worldwide infection that is an important cause of peptic ulcer disease and gastric cancer. H. pylori may also have a role in uninvestigated and functional dyspepsia, ulcer risk in patients taki...

Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and o...
British Journal of Haematology; Scully M, Hunt BJ et. al.

May 26th, 2012 - Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies.|2012|Scully M,Hunt BJ,Benjamin S,Liesner R,Rose P,|diagnosis,pathology,therapy,diagnosis,pathology,therapy,

Guidelines for the diagnosis and management of disseminated intravascular coagulation. ...
British Journal of Haematology; Levi M, Toh CH et. al.

Feb 19th, 2009 - The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and laboratory information. The International Society for Thrombosis and Haemostasis (ISTH) DIC scoring system provides objective measurement of DIC. Wher...

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Drugs  658 results see all →

Clinicaltrials.gov  260 results

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

Feb 1st, 2023 - Study duration per participant is approximately 2 months up to approximately 6 months in case of treatment extension and recurrence during the study drug treatment period.

IVIG (Gamunex-C) Treatment Study for POTS Subjects

Jan 30th, 2023 - Gammunex-C, a form of intravenous immunoglobulin (IVIG), is approved for the treatment of chronic inflammatory demyelinating neuropathy (CIDP) or idiopathic thrombocytopenic purpura (ITP). IVIG has been in use for many decades in the treatment of ...

A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)

Jan 30th, 2023 - Thrombotic thrombocytopenic purpura (or TTP for short) is a condition where blood clots form in small blood vessels throughout the body. The clots can limit or block the flow of oxygen-rich blood to the body's organs, such as the brain, kidneys, a...

Clinical Trial Analyzing the Efficacy of Oral Administration of Tranexamic Acid in Spine Surgery.

Jan 30th, 2023 - The study design is a prospective randomized control trial done in a single institution from 2021 to 2022. Approval from the institutional ethics committee was obtained for the study (number 04/21). Major surgery was defined as "surgeries involvin...

Long-term Sequelae of Childhood Meningitis and Meningococcal Purpura Fulminans

Jan 11th, 2023 - While the initial evolution of meningococcal meningitis (MM) is well described, there are few data on the long-term evolution, beyond 1 year. The objective of this research is to evaluate the sequelae of MM beyond 1 year in patients with a history...

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News  493 results

The Changes Made in the New Expert Consensus on H pylori

Nov 15th, 2022 - VIENNA ― Experts in Maastricht, the Netherlands, have updated the 2017 Helicobacter pylori consensus report, now referred to as the Maastricht VI/Florence Consensus Report. Published in August 2022, the document and its changes were recently addre...

From A to Y: Meningococcal Diseases and Vaccination

Nov 11th, 2022 - A vaccination campaign against meningococcal B bacteria has been launched in the Chambéry and Lyon-East regions of France. This campaign follows an increase in cases of infection since June 2022 with a new variant. According to recommendations, va...

Leukocytoclastic Vasculitis Masquerading as Chronic ITP
Saria Tasnim, MD, Hina Yousuf, MD et. al.

Nov 9th, 2022 - Idiopathic thrombocytopenic purpura (ITP) is an immune-mediated acquired condition affecting both adults and children. 1 Acute ITP is the most common form, which happens in the presence of a precipitant, leading to a drop in platelet counts.

Cracking the “MGUS” Code Reveals Monoclonal Gammopathy of Clinical Significance:

Nov 1st, 2022 - When assessing monoclonal gammopathy it is important to rule out clinically significant associations requiring treatment. On initial patient consultation, gathering a detailed patient history and thorough physical exam can catch clinically signifi...

Nonblanching Rash on the Legs and Chest
Karin Roszell, MD, Elisabeth A. Pedersen, MD, PhD et. al.

Oct 19th, 2022 - The Diagnosis: Leukemia Cutis Hematoxylin and eosin staining revealed an infiltration of monomorphic atypical myeloid cells with cleaved nuclei within the dermis, with a relatively uninvolved epidermis (Figure, A). The cells formed aggregates in s.

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Patient Education  36 results see all →