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About 780 results

ALLMedicine™ Gestational Trophoblastic Neoplasia Center

Research & Reviews  287 results

A Rare Case of Combined Choriocarcinoma and Placental Site Trophoblastic Tumor Presenti...
https://doi.org/10.12659/AJCR.936451
The American Journal of Case Reports; Chatterjee T, Martial A et. al.

Jun 19th, 2022 - BACKGROUND Despite the tendency to metastasize widely, Gestational Trophoblastic Neoplasia (GTN) is one of the most curable solid tumors with chemotherapy. CASE REPORT A 41-year-old female, G4P2A2, presented with a slowly growing lump on the left ...

Dostarlimab in Chemoresistant Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT05405192

Jun 6th, 2022 - The purpose of this study is to see if Dostarlimab is an effective treatment for Gestational Trophoblastic Neoplasia (GTN).

Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT05139095

May 31st, 2022 - The purpose of this study is to evaluate the efficacy and safety of camrelizumab and apatinib as combination therapy in patients with ultra high-risk and high-risk chemo-refractory or relapsed gestational trophoblastic neoplasia(GTN). Treatment ...

Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT04756713

May 27th, 2022 - This is a randomized, multicenter clinical trial including patients seen at one of 13 gestational trophoblastic disease reference centers in Brazil. Subjects are eligible if they have low-risk gestational trophoblastic neoplasia according to FIGO ...

The efficacy of immune checkpoint inhibitors in rare tumors: A systematic review of pub...
https://doi.org/10.1016/j.critrevonc.2022.103700
Critical Reviews in Oncology/hematology; Guven DC, Stephen B et. al.

May 10th, 2022 - The immune checkpoint inhibitors (ICIs) entered treatment algorithms in most tumors. However, the data on the efficacy is limited in rare tumors with no phase III studies. We systemically reviewed the clinical trials evaluating the ICI efficacy in...

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Guidelines  1 results

Gestational Trophoblastic Neoplasia, Version 2.2019, NCCN Clinical Practice Guidelines ...
https://doi.org/10.6004/jnccn.2019.0053
Journal of the National Comprehensive Cancer Network : JN... Abu-Rustum NR, Yashar CM et. al.

Nov 7th, 2019 - Gestational trophoblastic neoplasia (GTN), a subset of gestational trophoblastic disease (GTD), occurs when tumors develop in the cells that would normally form the placenta during pregnancy. The NCCN Guidelines for Gestational Trophoblastic Neopl...

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Drugs  4 results see all →

Clinicaltrials.gov  14 results

Dostarlimab in Chemoresistant Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT05405192

Jun 6th, 2022 - The purpose of this study is to see if Dostarlimab is an effective treatment for Gestational Trophoblastic Neoplasia (GTN).

Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT05139095

May 31st, 2022 - The purpose of this study is to evaluate the efficacy and safety of camrelizumab and apatinib as combination therapy in patients with ultra high-risk and high-risk chemo-refractory or relapsed gestational trophoblastic neoplasia(GTN). Treatment ...

Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT04756713

May 27th, 2022 - This is a randomized, multicenter clinical trial including patients seen at one of 13 gestational trophoblastic disease reference centers in Brazil. Subjects are eligible if they have low-risk gestational trophoblastic neoplasia according to FIGO ...

Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT04562558

Nov 16th, 2021 - The investigators conducted a randomized trial to study how well multi-day methotrexate protocol works compared to biweekly single-dose actinomycin D protocol in treating patients with low-risk gestational trophoblastic neoplasia. It is not yet kn...

Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia
https://clinicaltrials.gov/ct2/show/NCT01535053

Oct 20th, 2021 - PRIMARY OBJECTIVES: I. To test the hypothesis that treatment with multi-day methotrexate is inferior to treatment with pulse actinomycin-D (dactinomycin) in patients with low-risk gestational trophoblastic disease with respect to complete response...

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News  6 results

Evaluating phantom hCG and low-level hCG elevations in the nonpregnant patient
https://www.mdedge.com/obgyn/article/248045/gynecologic-cancer/evaluating-phantom-hcg-and-low-level-hcg-elevations
Emma C. Rossi, MD

Oct 28th, 2021 - A human chorionic gonadotropin (hCG) test is commonly ordered by gynecologists prior to surgical procedures, in the workup of bleeding abnormalities, and in the follow-up of ectopic and molar pregnancies, to name a few indications. In doing so, oc.

NCCN Guidelines Gain Traction Around the Globe
https://www.onclive.com/view/nccn-guidelines-gain-traction-around-the-globe

Dec 5th, 2020 - Robert W. Carlson, MD, CEO of NCCN Figure 1. Downloads of NCCN Guidelines up More Than 600% Since 2006 Global use of cancer management guidelines from the National Comprehensive Cancer Network (NCCN) has climbed rapidly in recent years. A rele...

Molar pregnancy: The next steps after diagnosis
https://www.mdedge.com/obgyn/article/216379/obstetrics/molar-pregnancy-next-steps-after-diagnosis
Emma Rossi, MD

Jan 29th, 2020 - Molar pregnancy is an uncommon but serious condition that affects young women of reproductive age. The diagnosis and management of molar pregnancy is familiar to most gynecologists.

First-ever gestational trophoblastic neoplasia guidelines published
https://www.mdedge.com/hematology-oncology/article/172712/gynecologic-cancer/first-ever-gestational-trophoblastic-neoplasia/page/0/1

Aug 15th, 2018 - Reassuring insurers Dr. Mutch said that he and his colleagues in GTN centers sometimes treat patients with intermediate or high-risk disease who were started on single-agent therapy or suboptimal therapies and present with advanced, drug-resistant.

First-ever gestational trophoblastic neoplasia guidelines published
https://www.mdedge.com/obgyn/article/172712/gynecologic-cancer/first-ever-gestational-trophoblastic-neoplasia-guidelines
Neil Osterweil

Aug 15th, 2018 - The National Comprehensive Cancer Network (NCCN) has issued its first-ever clinical practice guidelines for the treatment of gestational trophoblastic neoplasia (GTN), a rare, serious complication of pregnancy that can often be cured, but can have.

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