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About 1,518 results

ALLMedicine™ Vulvar Cancer Center

Research & Reviews  505 results

Neoadjuvant chemotherapy for patients with locally advanced vulvar cancer.
https://doi.org/10.1097/CCO.0000000000000861
Current Opinion in Oncology; Nooij L, Schaake E et. al.

Aug 10th, 2022 - Studies on treatment options for patients with locally advanced vulvar cancer (LAVC) are scarce, and high-level evidence for a primary treatment choice is lacking. Furthermore, current treatment options are associated with extensive morbidity and ...

Serial MRI Scans During Radiation Therapy
https://clinicaltrials.gov/ct2/show/NCT04188535

Aug 9th, 2022 - This phase 1, non randomized open label study, evaluating feasibility of serial MRI, with an option for an expansion cohort. The optional expansion cohort is a prospective imaging registry evaluating imaging biomarkers as predictors of disease con...

Electrochemotherapy as an Alternative Treatment Option to Pelvic Exenteration for Recur...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340424
Technology in Cancer Research & Treatment; Vivod G, Kovacevic N et. al.

Jul 29th, 2022 - Objective: Pelvic exenteration in women with recurrent vulvar carcinoma is associated with high morbidity and mortality and substantial treatment costs. Because pelvic exenteration severely affects the quality of life and can lead to significant c...

An Investigational Immuno-therapy Study to Investigate the Safety and Effectiveness of Nivolumab, and Nivolumab Combination Therapy in Virus-associated Tumors
https://clinicaltrials.gov/ct2/show/NCT02488759

Jul 7th, 2022 - The purpose of this study to investigate the safety and effectiveness of nivolumab, and nivolumab combination therapy, to treat patients who have virus-associated tumors. Certain viruses have been known to play a role in tumor formation and growth...

Contrast-Enhanced Ultrasound Imaging Scan for the Detection of Sentinel Lymph Nodes in Patients With Cervical, Vaginal, or Vulvar Cancer
https://clinicaltrials.gov/ct2/show/NCT05105087

Jul 7th, 2022 - PRIMARY OBJECTIVES: I. To determine the concordance between lymphosonography and the standard of care in the identification sentinel lymph nodes (SLNs) in patients with cervical, vaginal or vulvar cancer. II. To determine if lymphosonography can i...

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Guidelines  6 results

ACR Appropriateness Criteria® Staging and Follow-up of Vulvar Cancer.
https://doi.org/10.1016/j.jacr.2021.02.016
Journal of the American College of Radiology : JACR; , Lakhman Y et. al.

May 8th, 2021 - Vulvar cancer is an uncommon gynecologic tumor and one of several human papillomavirus-associated malignancies. Squamous cell carcinoma is the most prevalent histologic subtype of vulvar cancer, accounting for the majority of cases. Imaging plays ...

No. 370-Management of Squamous Cell Cancer of the Vulva.
https://doi.org/10.1016/j.jogc.2018.07.004
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Francis JA, Eiriksson L et. al.

Dec 26th, 2018 - This guideline reviews the clinical evaluation and management of squamous cell cancer (SCC) of the vulva with respect to diagnosis, primary surgical, radiation, or chemotherapy management and need for adjuvant treatment with chemotherapy and/or ra...

Japan Society of Gynecologic Oncology guidelines 2015 for the treatment of vulvar cance...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882649
International Journal of Clinical Oncology; Saito T, Tabata T et. al.

Nov 22nd, 2017 - Vulvar cancer and vaginal cancer are relatively rare tumors, and there had been no established treatment principles or guidelines to treat these rare tumors in Japan. The first version of the Japan Society of Gynecologic Oncology (JSGO) guidelines...

Vulvar Cancer, Version 1.2017, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2017.0008
Journal of the National Comprehensive Cancer Network : JN... Koh WJ, Greer BE et. al.

Jan 4th, 2017 - Vulvar cancer is a rare gynecologic malignancy. Ninety percent of vulvar cancers are predominantly squamous cell carcinomas (SCCs), which can arise through human papilloma virus (HPV)-dependent and HPV-independent pathways. The NCCN Vulvar Cancer ...

New NCCN Guidelines for Vulvar Cancer.
https://doi.org/10.6004/jnccn.2016.0184
Journal of the National Comprehensive Cancer Network : JN... Greer BE, Koh WJ

May 27th, 2016 - For the first time, NCCN Guidelines are available for vulvar cancer, a rare gynecologic cancer. Early-stage cancers can be managed by surgery and observation, and many of these patients can be cured. Lymph node status drives treatment and correlat...

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Clinicaltrials.gov  48 results

Serial MRI Scans During Radiation Therapy
https://clinicaltrials.gov/ct2/show/NCT04188535

Aug 9th, 2022 - This phase 1, non randomized open label study, evaluating feasibility of serial MRI, with an option for an expansion cohort. The optional expansion cohort is a prospective imaging registry evaluating imaging biomarkers as predictors of disease con...

An Investigational Immuno-therapy Study to Investigate the Safety and Effectiveness of Nivolumab, and Nivolumab Combination Therapy in Virus-associated Tumors
https://clinicaltrials.gov/ct2/show/NCT02488759

Jul 7th, 2022 - The purpose of this study to investigate the safety and effectiveness of nivolumab, and nivolumab combination therapy, to treat patients who have virus-associated tumors. Certain viruses have been known to play a role in tumor formation and growth...

Contrast-Enhanced Ultrasound Imaging Scan for the Detection of Sentinel Lymph Nodes in Patients With Cervical, Vaginal, or Vulvar Cancer
https://clinicaltrials.gov/ct2/show/NCT05105087

Jul 7th, 2022 - PRIMARY OBJECTIVES: I. To determine the concordance between lymphosonography and the standard of care in the identification sentinel lymph nodes (SLNs) in patients with cervical, vaginal or vulvar cancer. II. To determine if lymphosonography can i...

Screening Women With Prior HPV for Anal Neoplasia
https://clinicaltrials.gov/ct2/show/NCT05217940

Jun 30th, 2022 - This single arm trial will enroll 300 HIV uninfected women with a history of genital neoplasia (ie., cervical intraepithelial neoplasia grade 2-3, vaginal intraepithelial neoplasia grade 2-3 or vulvar intraepithelial neoplasia grade 2-3) or early ...

Electrochemotherapy With Carboplatinum Plus Bleomycin Versus Bleomycin Alone in Vulvar Cancer
https://clinicaltrials.gov/ct2/show/NCT05395962

May 27th, 2022 - Patients with vulvar cancer who underwent multiple treatments (surgery and radiation therapy or chemoradiation, radiation therapy or chemoradiation and chemotherapy), or patients not eligible for standard therapies. The study aims to: Evaluate the...

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News  39 results

Imiquimod Cream Offers Alternative to Surgery for Vulvar Lesions
https://www.medscape.com/viewarticle/974096

May 17th, 2022 - Imiquimod cream is a safe, effective, first-line alternative to surgery for the treatment of vulvar high-grade squamous intraepithelial lesions (vHSILs), suggest the results from the first randomized trial to compare the two approaches directly. T...

Topical Imiquimod as Good as Surgery for Vulvar Intraepithelial Neoplasia
https://www.medscape.com/viewarticle/972953

May 2nd, 2022 - NEW YORK (Reuters Health) - Topical imiquimod works just as well as surgery for the first-line treatment of women with vulvar high-grade squamous intraepithelial lesions (vHSILs) — a precancerous lesion commonly caused by human papillomavirus (HPV...

Sentinel Lymph Node Excision Has Value in Endometrial Cancer
https://www.onclive.com/view/sentinel-lymph-node-excision-has-value-in-endometrial-cancer

Oct 6th, 2021 - Sumer K. Wallace, MD Assistant Professor Department of Obstetrics and Gynecology Division of Gynecologic Oncology University of Wisconsin School of Medicine and Public Health at Madison With an estimated 63,230 new cases diagnosed in 201...

How Is Treatment Changing for Patients With Cervical Cancer? Three Experts Weigh In
https://www.onclive.com/view/how-is-treatment-changing-for-patients-with-cervical-cancer-three-experts-weigh-in

Dec 5th, 2020 - Richard T. Penson, MD Associate Professor Harvard Medical School Clinical Director, Medical and Gynecological Oncology Massachusetts General Hospital Boston, MA Q: We know that cisplatin and radiotherapy has been a standard of care in ...

Tinkering With Regimen Leads to Better Outcomes in Vulvar Cancer
https://www.onclive.com/view/tinkering-with-regimen-leads-to-better-outcomes-in-vulvar-cancer

Dec 5th, 2020 - David H. Moore, MD Investigators in a cooperative group trial reported that modifications in a chemoradiation regimen for locally advanced vulvar cancer boosted both clinical and pathologic complete response rates compared with historical result...

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Patient Education  9 results see all →