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About 5,081 results

ALLMedicine™ Neural Tube Defects Center

Research & Reviews  2,369 results

Single and mixed effects of metallic elements in maternal serum during pregnancy on ris...
https://doi.org/10.1016/j.envpol.2021.117203
Environmental Pollution (Barking, Essex : 1987); Tian T, Yin S et. al.

May 1st, 2021 - Studies of the association between prenatal exposure to metal elements and risk for neural tube defects (NTDs) have produced inconsistent results. Little research has examined the joint effects and interactions of multiple elements. This study exa...

Risk factors associated to neural tube defects among mothers who gave birth in North Sh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075213
PloS One; Gashaw A, Shine S et. al.

Apr 26th, 2021 - Neural tube defects affect the brain and the spinal cord of the developing embryo. The defects occur due to incomplete or failure of closure of the neural tube. The condition eventually causes death and lifelong disability. Worldwide, more than 30...

Birth prevalence of neural tube defects and associated risk factors in Africa: a system...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058994
BMC Pediatrics; Oumer M, Tazebew A et. al.

Apr 22nd, 2021 - Neural tube defects are common congenital anomalies that result from early malformation in the development of the spinal cord and brain. It is related to substantial mortality, morbidity, disability, and psychological and economic costs. The aim o...

Identification of new candidate genes for spina bifida through exome sequencing.
https://doi.org/10.1007/s00381-021-05153-4 10.1111/j.1399-0004.2007.00793.x 10.1016/j.ejrad.2003.10.015 10.1002/ddrr.93 10.1056/NEJM199309303291401 10.2174/092986709788453069 10.1111/cga.12227 10.1002/bdr2.1380 10.1093/oxfordjournals.bmb.a071187 10.1016/j.spen.2009.06.001 10.1016/S1474-4422(13)70110-8 10.1016/j.ntt.2004.12.007 10.1002/ajmg.c.30055 10.1002/bdra.20676 10.1136/jmedgenet-2015-103027 10.1002/humu.23214 10.1002/mgg3.467 10.1007/s00439-019-01993-y 10.3389/fnins.2019.01285 10.1007/s00381-016-3121-3 10.1186/gb-2010-11-8-r86 10.1093/bioinformatics/btp324 10.1038/nprot.2015.105 10.1093/bioinformatics/bty897 10.1083/jcb.124.5.855 10.1242/dev.065938 10.1006/taap.1997.8221 10.1002/mgg3.1258 10.1007/s00439-013-1372-6 10.1073/pnas.1322362111 10.1073/pnas.1804042116 10.1016/j.neuroscience.2020.07.015 10.1002/bdra.20686 10.1006/geno.1996.0124 10.1038/sj.bjc.6602962 10.1186/s12885-016-2185-5 10.1002/dvdy.93 10.18632/oncotarget.10429 10.1016/S0171-2985(97)80027-7 10.1073/pnas.212306199 10.1016/S0014-4827(03)00215-5 10.1111/j.1471-4159.2005.03542.x 10.1158/0008-5472.CAN-05-3840 10.1038/ng0598-74 10.1093/genetics/126.3.665 10.1016/S0736-5748(00)00071-X 10.1016/S0959-437X(97)80014-7 10.1083/jcb.152.6.1247 10.1016/j.cell.2006.02.045 10.1242/jcs.188417 10.1021/cn300008p 10.1016/0014-5793(96)00437-1 10.1093/hmg/ddy339 10.1002/dneu.22193 10.1002/bdra.23567 10.1126/sciadv.1600963 10.1073/pnas.98.4.1370 10.1101/gad.12.19.2992 10.1016/j.ydbio.2007.12.033 10.1093/hmg/9.13.2051
Child's Nervous System : ChNS : Official Journal of the I... Azzarà A, Rendeli C et. al.

Apr 15th, 2021 - Neural tube defects are a group of birth defects caused by failure of neural tube closure during development. The etiology of NTD, requiring a complex interaction between environmental and genetic factors, is not well understood. We performed whol...

Gestational Folate and Folic Acid Intake among Women in Canada at Higher Risk of Pre-Ec...
https://doi.org/10.1093/jn/nxab063
The Journal of Nutrition; Rose EG, Murphy MSQ et. al.

Apr 14th, 2021 - Periconceptional folic acid (FA) supplementation is recommended to prevent neural tube defects; however, the extent to which recommendations are met through dietary sources and supplements is not clear. Our objective was to evaluate the dietary an...

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Guidelines  25 results

Guideline No. 410: Prevention, Screening, Diagnosis, and Pregnancy Management for Fetal...
https://doi.org/10.1016/j.jogc.2020.11.003
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Douglas Wilson R, Van Mieghem T et. al.

Nov 19th, 2020 - This revised guideline is intended to provide an update on the genetic aspects, prevention, screening, diagnosis, and management of fetal neural tube defects. Women who are pregnant or may become pregnant. Neural tube defect screening should be of...

WHO recommends dolutegravir as preferred HIV treatment option in all populations
https://www.who.int/news-room/detail/22-07-2019-who-recommends-dolutegravir-as-preferred-hiv-treatment-option-in-all-populations

Jul 21st, 2019 - Based on new evidence assessing benefits and risks, the WHO recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potenti...

Teratology Society position statement on surveillance and prevalence estimation of neural tu...
https://onlinelibrary.wiley.com/doi/full/10.1002/bdr2.1434
Kancherla, V.,et al

Dec 18th, 2018 - In this position statement, the Teratology Society acknowledges the value of accurate measurement of total prevalence of neural tube defects (NTDs) in the population to support prevention, and advocates for rigorous surveillance world‐wide. NTDs,.

Practice Bulletin No. 187: Neural Tube Defects.
https://doi.org/10.1097/AOG.0000000000002412
Obstetrics and Gynecology;

Nov 30th, 2017 - Neural tube defects (NTDs) are congenital structural abnormalities of the central nervous system and vertebral column. Neural tube defects may occur as an isolated malformation, in combination with other malformations, as part of a genetic syndrom...

Folic Acid Supplementation for the Prevention of Neural Tube Defects: US Preventive Ser...
https://doi.org/10.1001/jama.2016.19438
JAMA , Bibbins-Domingo K et. al.

Jan 17th, 2017 - Neural tube defects are among the most common major congenital anomalies in the United States and may lead to a range of disabilities or death. Daily folic acid supplementation in the periconceptional period can prevent neural tube defects. Howeve...

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Clinicaltrials.gov  2,507 results

Single and mixed effects of metallic elements in maternal serum during pregnancy on ris...
https://doi.org/10.1016/j.envpol.2021.117203
Environmental Pollution (Barking, Essex : 1987); Tian T, Yin S et. al.

May 1st, 2021 - Studies of the association between prenatal exposure to metal elements and risk for neural tube defects (NTDs) have produced inconsistent results. Little research has examined the joint effects and interactions of multiple elements. This study exa...

Risk factors associated to neural tube defects among mothers who gave birth in North Sh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8075213
PloS One; Gashaw A, Shine S et. al.

Apr 26th, 2021 - Neural tube defects affect the brain and the spinal cord of the developing embryo. The defects occur due to incomplete or failure of closure of the neural tube. The condition eventually causes death and lifelong disability. Worldwide, more than 30...

Birth prevalence of neural tube defects and associated risk factors in Africa: a system...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058994
BMC Pediatrics; Oumer M, Tazebew A et. al.

Apr 22nd, 2021 - Neural tube defects are common congenital anomalies that result from early malformation in the development of the spinal cord and brain. It is related to substantial mortality, morbidity, disability, and psychological and economic costs. The aim o...

Identification of new candidate genes for spina bifida through exome sequencing.
https://doi.org/10.1007/s00381-021-05153-4 10.1111/j.1399-0004.2007.00793.x 10.1016/j.ejrad.2003.10.015 10.1002/ddrr.93 10.1056/NEJM199309303291401 10.2174/092986709788453069 10.1111/cga.12227 10.1002/bdr2.1380 10.1093/oxfordjournals.bmb.a071187 10.1016/j.spen.2009.06.001 10.1016/S1474-4422(13)70110-8 10.1016/j.ntt.2004.12.007 10.1002/ajmg.c.30055 10.1002/bdra.20676 10.1136/jmedgenet-2015-103027 10.1002/humu.23214 10.1002/mgg3.467 10.1007/s00439-019-01993-y 10.3389/fnins.2019.01285 10.1007/s00381-016-3121-3 10.1186/gb-2010-11-8-r86 10.1093/bioinformatics/btp324 10.1038/nprot.2015.105 10.1093/bioinformatics/bty897 10.1083/jcb.124.5.855 10.1242/dev.065938 10.1006/taap.1997.8221 10.1002/mgg3.1258 10.1007/s00439-013-1372-6 10.1073/pnas.1322362111 10.1073/pnas.1804042116 10.1016/j.neuroscience.2020.07.015 10.1002/bdra.20686 10.1006/geno.1996.0124 10.1038/sj.bjc.6602962 10.1186/s12885-016-2185-5 10.1002/dvdy.93 10.18632/oncotarget.10429 10.1016/S0171-2985(97)80027-7 10.1073/pnas.212306199 10.1016/S0014-4827(03)00215-5 10.1111/j.1471-4159.2005.03542.x 10.1158/0008-5472.CAN-05-3840 10.1038/ng0598-74 10.1093/genetics/126.3.665 10.1016/S0736-5748(00)00071-X 10.1016/S0959-437X(97)80014-7 10.1083/jcb.152.6.1247 10.1016/j.cell.2006.02.045 10.1242/jcs.188417 10.1021/cn300008p 10.1016/0014-5793(96)00437-1 10.1093/hmg/ddy339 10.1002/dneu.22193 10.1002/bdra.23567 10.1126/sciadv.1600963 10.1073/pnas.98.4.1370 10.1101/gad.12.19.2992 10.1016/j.ydbio.2007.12.033 10.1093/hmg/9.13.2051
Child's Nervous System : ChNS : Official Journal of the I... Azzarà A, Rendeli C et. al.

Apr 15th, 2021 - Neural tube defects are a group of birth defects caused by failure of neural tube closure during development. The etiology of NTD, requiring a complex interaction between environmental and genetic factors, is not well understood. We performed whol...

Gestational Folate and Folic Acid Intake among Women in Canada at Higher Risk of Pre-Ec...
https://doi.org/10.1093/jn/nxab063
The Journal of Nutrition; Rose EG, Murphy MSQ et. al.

Apr 14th, 2021 - Periconceptional folic acid (FA) supplementation is recommended to prevent neural tube defects; however, the extent to which recommendations are met through dietary sources and supplements is not clear. Our objective was to evaluate the dietary an...

see more →

News  169 results

Folic Acid Supplementation Throughout Pregnancy: Neurocognitive Developmental Benefits for Children
https://www.medscape.com/viewarticle/948341

Mar 29th, 2021 - Takeaway Continued folic acid (FA) supplementation in pregnancy beyond the early period currently recommended to prevent neural tube defects (NTD) is beneficial to neurocognitive development in the child. Study also demonstrated the application of...

'Time to Lay to Rest' Fears About Dolutegravir Birth Defects
https://www.medscape.com/viewarticle/933586

Jul 7th, 2020 - The longer researchers have looked for evidence of neural tube defects linked with dolutegravir treatment of HIV at the time of conception the fewer incident cases they've found. The newest data, based on 3,591 deliveries among women in Botswana i...

Women with epilepsy: 5 clinical pearls for contraception and preconception counseling
https://www.mdedge.com/obgyn/article/207555/contraception/women-epilepsy-5-clinical-pearls-contraception-and-preconception/page/0/2?channel=61

Sep 4th, 2019 - 5. Folic acid: Although the optimal dose for WWE taking an AED and planning to become pregnant is unknown, a high dose is reasonable.

New WHO recommendations promote dolutegravir benefits in the face of lowered risk signal for neural tube defects
https://www.mdedge.com/jcomjournal/article/205126/hiv/new-who-recommendations-promote-dolutegravir-benefits-face-lowered?channel=53
Andrew D. Bowser

Jul 22nd, 2019 - The risk of neural tube defects linked to dolutegravir exposure during pregnancy is lower than previously signaled, according to new reports that have prompted the World Health Organization (WHO) to confirm that this antiviral medication should be.

WHO recommends dolutegravir as preferred HIV treatment option in all populations
https://www.who.int/news-room/detail/22-07-2019-who-recommends-dolutegravir-as-preferred-hiv-treatment-option-in-all-populations

Jul 21st, 2019 - Based on new evidence assessing benefits and risks, the WHO recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potenti...

see more →

Patient Education  11 results see all →