×
About 20,168 results

ALLMedicine™ Osteosarcoma Center

Research & Reviews  9,913 results

Circ_0000527 promotes osteosarcoma cell progression through modulating miR-646/ARL2 axis.
https://doi.org/10.18632/aging.202602
Aging Wu X, Yan L et. al.

Feb 22nd, 2021 - Accumulating evidence shows that circRNAs play critical roles in the development of human tumors. We observed that circ_0000527 was overexpressed in osteosarcoma cells (SAOS-2, HOS, MG-63 and U2OS) compared in hFOB1.19 cells. We demonstrated that ...

Evaluation of Virola oleifera activity in musculoskeletal pathologies: inhibition of hu...
https://doi.org/10.1016/j.jep.2021.113932
Journal of Ethnopharmacology; Francisco V, Ruiz-Fernández C et. al.

Feb 20th, 2021 - Virola oleifera (Schott) A.C. Smith, Myristicaceae, has been widely used in traditional medicine in Brazil to treat rheumatic pain, joint tumours, skin diseases, halitosis, bronchial asthma, haemorrhoids, and intestinal worms. Recently, research d...

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel ci...
https://doi.org/10.1038/s41388-021-01686-9 10.1002/ijc.24320 10.1007/s40744-016-0046-y 10.1200/JCO.2002.20.3.776 10.7326/0003-4819-71-4-747 10.1002/cncr.26390 10.1038/ncb2641 10.1101/gad.1339905 10.1101/cshperspect.a026039 10.1038/ncb1928 10.1038/onc.2012.242 10.1080/17460441.2020.1757644 10.1016/j.theriogenology.2016.04.058 10.3390/ijms21020488 10.1002/adfm.201904992 10.1016/S0960-9822(00)00002-6 10.1038/onc.2012.610 10.1016/j.ccr.2005.04.023 10.1038/90108 10.1038/nature10937 10.1371/journal.pone.0043323 10.1038/oncsis.2016.19 10.1038/nrc2731 10.1016/j.cell.2004.11.004 10.1016/j.cell.2004.11.006 10.3389/fonc.2014.00189 10.1136/vr.148.5.147 10.1016/j.febslet.2010.10.005 10.1002/stem.1733 10.1002/ijc.30603 10.1016/j.cell.2016.05.052 10.1080/10409238.2017.1380597 10.1038/ng.3900 10.1074/jbc.C000781200 10.1002/mc.22441 10.1186/s12943-017-0719-3 10.1186/s13059-018-1594-y 10.1111/j.1365-2230.2008.02851.x 10.1038/38298 10.1016/j.ccr.2005.02.019 10.4161/cbt.5.7.3023 10.18632/aging.100441 10.1038/cddis.2015.149 10.1182/blood-2010-11-321851 10.4161/cc.11.3.19054 10.1038/nrc.2017.109 10.3390/ijms20246257 10.3892/mmr.2017.6162 10.1038/bjc.2011.433 10.3892/ijo.2013.1818 10.1093/carcin/bgt411 10.15252/embr.201541956 10.1172/JCI75447 10.1038/onc.2014.359 10.1073/pnas.1913919116 10.1387/ijdb.150045sg 10.1182/blood-2015-01-623330 10.1016/j.cell.2015.05.001
Oncogene Niu G, Hellmuth I et. al.

Feb 19th, 2021 - Recent years have seen an increasing number of genetically engineered pig models of human diseases including cancer. We previously generated pigs with a modified TP53 allele that carries a Cre-removable transcriptional stop signal in intron 1, and...

MPP8 Promotes Proliferation and Restrains Apoptosis in Osteosarcoma by Regulating p38αM...
https://doi.org/10.1177/1533033821995272
Technology in Cancer Research & Treatment; Li T, Li N et. al.

Feb 18th, 2021 - Osteosarcoma is the most common primary bone malignancy. We aim to investigate that role of M-phase phosphoprotein 8 (MPP8) on proliferation and apoptosis in osteosarcoma. Briefly, the current research reported an in vitro study investigating the ...

The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma.
https://doi.org/10.1111/nyas.14578
Annals of the New York Academy of Sciences; Wang J, Aldahamsheh O et. al.

Feb 17th, 2021 - Osteosarcoma is a highly aggressive malignancy for which treatment has remained essentially unchanged for years. Our previous studies found that the F-box protein SKP2 is overexpressed in osteosarcoma, acting as a proto-oncogene; p27Kip1 (p27) is ...

see more →

Guidelines  9 results

Osteosarcoma and Malignant Fibrous Histiocytoma of Bone Treatment (PDQ®)–Health Professional Version
https://www.cancer.gov/types/bone/hp/osteosarcoma-treatment-pdq?cid=eb_govdel

Aug 21st, 2019 - Osteosarcoma and malignant fibrous histiocytoma (MFH) of bone treatment depends on site, extent of disease, and grade. Treatment options include surgery, chemotherapy, radiation therapy, and targeted therapy. Get detailed treatment information for...

Triassic Cancer—Osteosarcoma in a 240-Million-Year-Old Stem-Turtle
https://jamanetwork.com/journals/jamaoncology/fullarticle/2723578
Hairdy,Y.,et al

Feb 6th, 2019 - Paleopathology, the study of ancient disease, is a vital way by which we understand the evolution of pathogens, immune systems, healing physiology, and ultimately the environment. Cancer research has focused on its prevalence in various organisms ...

NCCN Guidelines Insights: Bone Cancer, Version 2.2017
http://www.jnccn.org/content/15/2/155.full
Biermann, J.,et al

Jan 31st, 2017 - The NCCN Guidelines for Bone Cancer provide interdisciplinary recommendations for treating chordoma, chondrosarcoma, giant cell tumor of bone, Ewing sarcoma, and osteosarcoma. These NCCN Guidelines Insights summarize the NCCN Bone Cancer Panel's g.

ENCCA WP17-WP7 consensus paper on teenagers and young adults (TYA) with bone sarcomas.
https://doi.org/10.1093/annonc/mdu153
Annals of Oncology : Official Journal of the European Soc... Wilhelm M, Dirksen U et. al.

Jun 25th, 2014 - Teenagers and young adults (TYA) cancer contributes substantially to morbidity and mortality in a population with much to offer society. TYA place distinct challenges upon cancer care services, many reporting feeling marginalized and their needs n...

SEOM clinical guidelines for the treatment of osteosarcoma in adults-2013.
https://doi.org/10.1007/s12094-013-1087-0
Clinical & Translational Oncology : Official Publication ... Redondo A, Cruz J et. al.

Aug 2nd, 2013 - The diagnosis and treatment of osteosarcoma should be performed by an experienced multidisciplinary team. Considering it is a systemic disease, chemotherapy is essential for long-term success. The drugs most commonly used are: cisplatin, adriamyci...

see more →

Drugs  59 results see all →

Clinicaltrials.gov  10,083 results

Circ_0000527 promotes osteosarcoma cell progression through modulating miR-646/ARL2 axis.
https://doi.org/10.18632/aging.202602
Aging Wu X, Yan L et. al.

Feb 22nd, 2021 - Accumulating evidence shows that circRNAs play critical roles in the development of human tumors. We observed that circ_0000527 was overexpressed in osteosarcoma cells (SAOS-2, HOS, MG-63 and U2OS) compared in hFOB1.19 cells. We demonstrated that ...

Evaluation of Virola oleifera activity in musculoskeletal pathologies: inhibition of hu...
https://doi.org/10.1016/j.jep.2021.113932
Journal of Ethnopharmacology; Francisco V, Ruiz-Fernández C et. al.

Feb 20th, 2021 - Virola oleifera (Schott) A.C. Smith, Myristicaceae, has been widely used in traditional medicine in Brazil to treat rheumatic pain, joint tumours, skin diseases, halitosis, bronchial asthma, haemorrhoids, and intestinal worms. Recently, research d...

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel ci...
https://doi.org/10.1038/s41388-021-01686-9 10.1002/ijc.24320 10.1007/s40744-016-0046-y 10.1200/JCO.2002.20.3.776 10.7326/0003-4819-71-4-747 10.1002/cncr.26390 10.1038/ncb2641 10.1101/gad.1339905 10.1101/cshperspect.a026039 10.1038/ncb1928 10.1038/onc.2012.242 10.1080/17460441.2020.1757644 10.1016/j.theriogenology.2016.04.058 10.3390/ijms21020488 10.1002/adfm.201904992 10.1016/S0960-9822(00)00002-6 10.1038/onc.2012.610 10.1016/j.ccr.2005.04.023 10.1038/90108 10.1038/nature10937 10.1371/journal.pone.0043323 10.1038/oncsis.2016.19 10.1038/nrc2731 10.1016/j.cell.2004.11.004 10.1016/j.cell.2004.11.006 10.3389/fonc.2014.00189 10.1136/vr.148.5.147 10.1016/j.febslet.2010.10.005 10.1002/stem.1733 10.1002/ijc.30603 10.1016/j.cell.2016.05.052 10.1080/10409238.2017.1380597 10.1038/ng.3900 10.1074/jbc.C000781200 10.1002/mc.22441 10.1186/s12943-017-0719-3 10.1186/s13059-018-1594-y 10.1111/j.1365-2230.2008.02851.x 10.1038/38298 10.1016/j.ccr.2005.02.019 10.4161/cbt.5.7.3023 10.18632/aging.100441 10.1038/cddis.2015.149 10.1182/blood-2010-11-321851 10.4161/cc.11.3.19054 10.1038/nrc.2017.109 10.3390/ijms20246257 10.3892/mmr.2017.6162 10.1038/bjc.2011.433 10.3892/ijo.2013.1818 10.1093/carcin/bgt411 10.15252/embr.201541956 10.1172/JCI75447 10.1038/onc.2014.359 10.1073/pnas.1913919116 10.1387/ijdb.150045sg 10.1182/blood-2015-01-623330 10.1016/j.cell.2015.05.001
Oncogene Niu G, Hellmuth I et. al.

Feb 19th, 2021 - Recent years have seen an increasing number of genetically engineered pig models of human diseases including cancer. We previously generated pigs with a modified TP53 allele that carries a Cre-removable transcriptional stop signal in intron 1, and...

MPP8 Promotes Proliferation and Restrains Apoptosis in Osteosarcoma by Regulating p38αM...
https://doi.org/10.1177/1533033821995272
Technology in Cancer Research & Treatment; Li T, Li N et. al.

Feb 18th, 2021 - Osteosarcoma is the most common primary bone malignancy. We aim to investigate that role of M-phase phosphoprotein 8 (MPP8) on proliferation and apoptosis in osteosarcoma. Briefly, the current research reported an in vitro study investigating the ...

The interaction of SKP2 with p27 enhances the progression and stemness of osteosarcoma.
https://doi.org/10.1111/nyas.14578
Annals of the New York Academy of Sciences; Wang J, Aldahamsheh O et. al.

Feb 17th, 2021 - Osteosarcoma is a highly aggressive malignancy for which treatment has remained essentially unchanged for years. Our previous studies found that the F-box protein SKP2 is overexpressed in osteosarcoma, acting as a proto-oncogene; p27Kip1 (p27) is ...

see more →

News  83 results

Tumor Profiling Yields Insights Into Poor Osteosarcoma Response to Immunotherapy
https://www.medscape.com/viewarticle/926055

Mar 2nd, 2020 - NEW YORK (Reuters Health) - Multiple genetic and cellular factors contribute to osteosarcoma's poor response to immunotherapy, researchers say. "Despite its genomic complexity, treatment with immune checkpoint inhibitors has been ineffective for p...

Osteosarcoma and Malignant Fibrous Histiocytoma of Bone Treatment (PDQ®)–Health Professional Version
https://www.cancer.gov/types/bone/hp/osteosarcoma-treatment-pdq?cid=eb_govdel

Aug 21st, 2019 - Osteosarcoma and malignant fibrous histiocytoma (MFH) of bone treatment depends on site, extent of disease, and grade. Treatment options include surgery, chemotherapy, radiation therapy, and targeted therapy. Get detailed treatment information for...

From the journals: sarcoma around the world
https://www.mdedge.com/sarcomajournal/article/203054/sarcoma/journals-sarcoma-around-world/page/0/2?channel=50183

Jun 17th, 2019 - PEDIATRIC OSTEOSARCOMA IN LEBANON: Investigators at a single institution in Lebanon reported a similar survival rate for newly diagnosed patients with pediatric osteosarcoma treated at their center as for those treated in more developed countries.

Wolf in sheep’s clothing: metatarsal osteosarcoma
https://www.mdedge.com/sarcomajournal/article/203028/osteosarcoma/wolf-sheeps-clothing-metatarsal-osteosarcoma/page/0/2?channel=47427

Jun 17th, 2019 - Conclusions Osteosarcoma of the metatarsal is rare. Our case remains unique as it reports the second youngest patient in the literature.

An unusual presentation of low-grade clavicle osteosarcoma: a case report and literature review
https://www.mdedge.com/sarcomajournal/article/203016/osteosarcoma/unusual-presentation-low-grade-clavicle-osteosarcoma-case/page/0/2?channel=47427

Jun 17th, 2019 - Radiographs can be misleading as well. Prior studies have demonstrated that low-grade central OS can be readily misdiagnosed as fibrous dysplasia, desmoplastic fibroma, nonossifying fibroma, osteoblastoma, and aneurysmal bone cyst.

see more →

Patient Education  21 results see all →