ALLMedicine™ Metastatic Bone Disease Center

May 1st, 2022 - Prognostic indicators, treatments, and survival estimates vary by cancer type. Therefore, disease-specific models are needed to estimate patient survival. Our primary aim was to develop models to estimate survival duration after treatment for skel...

Mar 25th, 2022 - Bone metastases induce pain, risk of fracture, and neural compression, and reduced mobility and quality of life. Electrochemotherapy (ECT) is a minimally invasive local treatment based on a high-voltage electric pulse combined with an anticancer d...

Feb 13th, 2022 - Radiation utilization for breast cancer and metastatic bone disease varies in modality, fractionation, and cost, despite evidence demonstrating equal effectiveness and consensus recommendations such as Choosing Wisely that advocate for higher valu...

Feb 10th, 2022 - The pelvis is one of the most common locations for metastatic bone disease. While many of the publications that describe surgical treatments focus on periacetabular lesions (Enneking zone II), there is a lack of investigation into lesions in the n...

Jan 14th, 2022 - We present the case of a 48-year-old man diagnosed with metastatic Ewing sarcoma who was referred for 18F-FDG PET/CT for treatment response evaluation following chemoradiotherapy. The patient also had complaints of new-onset testicular swelling at...

Nov 8th, 2021 - Bone scintigraphy scans are two dimensional medical images that are used heavily in nuclear medicine. The scans detect changes in bone metabolism with high sensitivity, yet it lacks the specificity to underlying causes. Therefore, further imaging ...

Aug 4th, 2020 - The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in comp...

Aug 16th, 2017 - This single arm study will assess the efficacy of loading doses of intravenous Bondronat in reducing pain in patients with breast cancer and metastatic bone disease experiencing moderate to severe bone pain. Patients will receive an intravenous in...

Aug 1st, 2017 - The purpose of this study is to collect safety and performance data of the Photodynamic Bone Stabilization System (PBSS) when used for the treatment of painful impending and actual fractures of the humerus secondary to metastatic cancer.

Jan 10th, 2017 - Bone is the most common site for metastasis. In breast and prostate cancers, 70% of patients dying of their cancer have evidence of metastatic bone disease [Coleman, 2006]. Depending on their localization, bone metastases can have debilitating con...

Feb 15th, 2022 - Medical oncologists who have patients with metastatic bone cancer should consult with orthopedic surgeons and interventional radiologists to provide patients with improved or minimally invasive therapeutic options, according to R. Lor Randall, MD....

Oct 6th, 2021 - R. Lor Randall, MD, FACS Orthopedic oncologists are the stewards of the musculoskeletal system, according to R. Lor Randall, MD, FACS. Therefore, he said, more medical oncologists should refer their patients with metastatic bone disease to orthop...

Sep 3rd, 2021 - Guidelines on the interventional management of cancer-associated pain were published in July 2021 by the American Society of Pain and Neuroscience in the Journal of Pain Research.[1] Opioids Consider using opioids for patients with moderate-to-sev...

Dec 20th, 2020 - The latest research on several investigational cancer therapies was presented at the European Society for Medical Oncology (ESMO) 2012 Congress, which took place from September 28-October 2 in Vienna, Austria. Below is a highlight of several key p...

Dec 20th, 2020 - Adam M. Brufsky, MD, PhD Certain bone-targeted agents deserve more frequent use in oncology, although providers need to be mindful about patient conditions and the potential for osteonecrosis, said Adam M. Brufsky, MD, PhD, who provided an update...