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About 143 results

ALLMedicine™ Pediatric Osteosarcoma Center

Research & Reviews  53 results

Pediatric Osteosarcoma: Correlation of Imaging Findings with Histopathologic Features, ...
https://doi.org/10.1148/rg.210171
Radiographics : a Review Publication of the Radiological ... Nguyen JC, Baghdadi S et. al.

May 21st, 2022 - Osteosarcoma is the most common primary bone sarcoma in children. Imaging plays a pivotal role in diagnostic workup, surgical planning, and follow-up monitoring for possible disease relapse. Survival depends on multiple factors, including presence...

Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity
https://clinicaltrials.gov/ct2/show/NCT03139318

Apr 20th, 2022 - Subjects will receive GRID radiotherapy. GRID radiation therapy is considered a standard radiation therapy method however is not typically used in pediatric osteosarcoma patients. This protocol will evaluate whether or not the use of this therapy ...

In Situ Analysis of mTORC1/C2 and Metabolism-Related Proteins in Pediatric Osteosarcoma.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980219
Pathology Oncology Research : POR; Mohás A, Krencz I et. al.

Apr 9th, 2022 - Activation of the mTOR pathway has been observed in osteosarcoma, however the inhibition of mammalian target of rapamycin (mTOR) complex 1 has had limited results in osteosarcoma treatment. Certain metabolic pathways can be altered by mTOR activat...

Does a single dose of palonosetron have any role in preventing acute chemotherapy-induc...
https://doi.org/10.17219/acem/142332
Advances in Clinical and Experimental Medicine : Official... Li Z, Li C et. al.

Mar 19th, 2022 - Chemotherapy-induced nausea and vomiting (CINV) is a troublesome side-effect of chemotherapy in pediatric patients undergoing osteosarcoma treatment. In this context, the role of 5-hydroxytryptamine-3 (5-HT3) receptor antagonists needs to be explo...

Discovery and Characterization of Intercondylar Transphyseal Complexes and their Oncolo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8867409
Orthopaedic Surgery; Shao XH, Li JM et. al.

Feb 25th, 2022 - To explore whether there exist undiscovered transphyseal vasculature-canal compound structures in immature femurs and tibias, and reveal their potential oncological impact. This investigation was divided into a morphological study and a clinical s...

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Clinicaltrials.gov  2 results

Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity
https://clinicaltrials.gov/ct2/show/NCT03139318

Apr 20th, 2022 - Subjects will receive GRID radiotherapy. GRID radiation therapy is considered a standard radiation therapy method however is not typically used in pediatric osteosarcoma patients. This protocol will evaluate whether or not the use of this therapy ...

A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin Lymphoma
https://clinicaltrials.gov/ct2/show/NCT04283955

Feb 25th, 2020 - INTRODUCTION: Non-Hodgkin lymphoma (NHL), the fourth most common malignancy across the pediatric age spectrum, is a heterogeneous group of lymphoid malignancies. In children, NHL comprises four main wide categories: lymphoblastic lymphoma (LBL), B...

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News  2 results

Pediatric Osteosarcoma Harbors a High Incidence of Pathogenic TP53 Variants
https://www.onclive.com/view/pediatric-osteosarcoma-harbors-a-high-incidence-of-pathogenic-tp53-variants

Oct 19th, 2020 - TP53 was found to be the only gene with a germline de novo pathogenic or likely pathogenic variant in pediatric patients with osteosarcoma, according to findings from the Children’s Oncology Group that were published in JCO Precision Oncology. ...

From the journals: sarcoma around the world
https://www.mdedge.com/sarcomajournal/article/203054/sarcoma/journals-sarcoma-around-world/page/0/2?channel=50183

Jun 17th, 2019 - PEDIATRIC OSTEOSARCOMA IN LEBANON: Investigators at a single institution in Lebanon reported a similar survival rate for newly diagnosed patients with pediatric osteosarcoma treated at their center as for those treated in more developed countries.

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