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ALLMedicine™ Breast Cancer Center

Research & Reviews  178,621 results

Distress Thermometer in breast cancer: systematic review and meta-analysis.
https://doi.org/10.1136/bmjspcare-2021-002960
BMJ Supportive & Palliative Care; Sun H, Lv H et. al.

May 12th, 2021 - This meta-analysis aimed to reach a summarised estimate of distress prevalence screened by Distress Thermometer (DT) among patients with breast cancer and compare different pooled prevalence estimated between different subgroups. Two independent i...

The MNK1/2-eIF4E axis supports immune suppression and metastasis in postpartum breast c...
https://doi.org/10.1158/0008-5472.CAN-20-3143
Cancer Research; Guo Q, Bartish M et. al.

May 12th, 2021 - Breast cancer diagnosed within 10 years following childbirth is defined as postpartum breast cancer (PPBC) and is highly metastatic. Interactions between immune cells and other stromal cells within the involuting mammary gland are fundamental in f...

Phenotypic heterogeneity and metastasis of breast cancer cells.
https://doi.org/10.1158/0008-5472.CAN-20-1799
Cancer Research; Hapach LA, Carey SP et. al.

May 12th, 2021 - While intratumoral genomic heterogeneity can impede cancer research and treatment, less is known about the effects of phenotypic heterogeneities. To investigate the role of cell migration heterogeneities in metastasis, we phenotypically sorted met...

Breast-Conserving Therapy in Patients with cT3 Breast Cancer with Good Response to Neoa...
https://doi.org/10.1245/s10434-021-09865-4 10.1093/jnci/dji021 10.1200/JCO.2007.15.0235 10.1097/SLA.0000000000000924 10.1002/cncr.25152 10.1200/JCO.2010.31.1258 10.1093/jncimonographs/lgv012 10.1056/NEJMp1205737 10.1001/jamaoncol.2015.1293 10.1016/S0140-6736(13)62422-8 10.1056/NEJMoa1910549 10.1001/jamaoncol.2019.6650 10.1016/S1470-2045(18)30570-9 10.1056/NEJMoa1513750 10.1007/s10549-018-5007-4 10.1016/j.ejca.2010.07.043 10.1200/JCO.2000.18.8.1668 10.1016/j.ijrobp.2007.11.029 10.1097/01.sla.0000197714.14318.6f 10.1038/nrclinonc.2015.63 10.1148/radiol.2017170180 10.1016/j.ejso.2015.01.022 10.1002/bjs.9962 10.1245/s10434-013-2921-x 10.1097/SLA.0000000000000558 10.1245/s10434-018-6404-y 10.1002/bjs.10555 10.1111/j.1365-2559.2006.02419.x 10.1056/NEJMoa0906260 10.1016/j.ijrobp.2013.11.012 10.1097/01.PRS.0000117191.10766.95 10.1007/s10549-006-9325-6 10.1097/MD.0000000000008367 10.1001/jamasurg.2014.2895 10.1111/tbj.12811 10.1016/j.crad.2018.05.026 10.1200/JCO.2011.38.8595 10.1016/j.clinimag.2019.05.006 10.3233/BD-150195 10.1245/s10434-015-4603-3 10.1016/j.jamcollsurg.2007.12.025 10.1245/s10434-009-0402-z 10.1007/BF02573059 10.1016/j.amjsurg.2009.01.006 10.1007/s10549-017-4117-8 10.1007/s10549-009-0616-6 10.1016/j.ejca.2017.05.012 10.1056/NEJMoa022152 10.1056/NEJMoa052122 10.1016/S0140-6736(11)61629-2 10.1200/JCO.2008.19.8424 10.1016/j.radonc.2008.05.002 10.1016/j.ejca.2014.12.003 10.1200/JCO.1997.15.3.963
Annals of Surgical Oncology; van der Noordaa MEM, Ioan I et. al.

May 12th, 2021 - Many cT3 breast cancer patients are treated with mastectomy, regardless of response to neoadjuvant systemic therapy (NST). We evaluated local control of cT3 patients undergoing breast-conserving therapy (BCT) based on magnetic resonance imaging (M...

FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple...
https://doi.org/10.1038/s41467-021-22618-x 10.1186/s12916-019-1326-5 10.1111/tbj.13696 10.1038/s41467-020-19540-z 10.1056/NEJMc1900150 10.6004/jnccn.2020.7554 10.1038/nrc3982 10.1038/s41467-020-19052-w 10.1016/j.bbrc.2009.11.098 10.1126/sciadv.aax8930 10.1038/ncomms12632 10.1038/s41467-020-14794-z 10.1073/pnas.1220425110 10.1371/journal.pone.0200315 10.1016/j.molonc.2009.12.001 10.1038/85339 10.4049/jimmunol.0904020 10.1371/journal.pone.0130126 10.1073/pnas.0405025101 10.1002/eji.200839028 10.1038/cr.2017.90 10.1038/ni967 10.1038/s41389-020-00293-9 10.3892/mmr.2012.1158 10.7150/ijbs.41105 10.1007/s10549-009-0674-9 10.1007/s10549-011-1457-7 10.1186/gb-2010-11-2-r18 10.1186/1471-2164-7-96 10.1002/ijc.28474 10.1073/pnas.1516991112 10.1093/glycob/cwx034 10.1093/glycob/cwl079 10.1016/j.celrep.2017.07.027 10.1186/s13058-017-0904-8 10.1038/s41467-020-17395-y 10.1038/s41467-020-20243-8 10.1038/nchembio.999 10.1016/j.celrep.2017.07.027 10.1074/jbc.M115.679852 10.1007/s11060-009-0038-7 10.1158/1078-0432.CCR-12-0715 10.1200/JCO.20.01974 10.1038/s41591-020-0821-8 10.1080/15548627.2017.1381804 10.1073/pnas.1107385108 10.1245/s10434-014-3564-2 10.1038/s41598-018-25357-0 10.1038/nature11412 10.1093/nar/gky1106
Nature Communications; Huang Y, Zhang HL et. al.

May 12th, 2021 - Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1 immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a highly glycosylated protein. However, the mechanisms of B7H3 glycosylat...

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Guidelines  893 results

Breastfeeding Challenges: ACOG Committee Opinion, Number 820.
https://doi.org/10.1097/AOG.0000000000004253
Obstetrics and Gynecology;

Jan 22nd, 2021 - Breastfeeding is associated with a decrease in a woman's risk of breast cancer, ovarian cancer, diabetes mellitus, and hypertensive heart disease. Breastfeeding initiation rates in the United States are increasing, and many women are aware of the ...

Real-World Experiences With Yoga on Cancer-Related Symptoms in Women With Breast Cancer
https://pubmed.ncbi.nlm.nih.gov/33473331/
Global Advances in Health and Medicine; Patel SR, Zayas J et. al.

Jan 6th, 2021 - Integrative therapies such as yoga are potential treatments for many psychological and physical symptoms that occur during and/or after treatment for cancer. The purpose of the current study was to evaluate the patient-perceived benefit of yoga fo...

Breast conservation and axillary management after primary systemic therapy in patients ...
https://doi.org/10.1016/S1470-2045(20)30580-5
The Lancet. Oncology; Dubsky P, Pinker K et. al.

Jan 2nd, 2021 - Primary systemic therapy is increasingly used in the treatment of patients with early-stage breast cancer, but few guidelines specifically address optimal locoregional therapies. Therefore, we established an international consortium to discuss cli...

Breast cancer risk factors and their effects on survival: a Mendelian randomisation study
https://pubmed.ncbi.nlm.nih.gov/33198768/
BMC Medicine; Escala-Garcia M

Nov 16th, 2020 - Observational studies have investigated the association of risk factors with breast cancer prognosis. However, the results have been conflicting and it has been challenging to establish causality due to potential residual confounding. Using a Mend...

ACR Appropriateness Criteria® Imaging After Mastectomy and Breast Reconstruction.
https://doi.org/10.1016/j.jacr.2020.09.009
Journal of the American College of Radiology : JACR; , Heller SL et. al.

Nov 6th, 2020 - Mastectomy may be performed to treat breast cancer or as a prophylactic approach in women with a high risk of developing breast cancer. In addition, mastectomies may be performed with or without reconstruction. Reconstruction approaches differ and...

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Drugs  987 results see all →

Clinicaltrials.gov  195,305 results

Distress Thermometer in breast cancer: systematic review and meta-analysis.
https://doi.org/10.1136/bmjspcare-2021-002960
BMJ Supportive & Palliative Care; Sun H, Lv H et. al.

May 12th, 2021 - This meta-analysis aimed to reach a summarised estimate of distress prevalence screened by Distress Thermometer (DT) among patients with breast cancer and compare different pooled prevalence estimated between different subgroups. Two independent i...

The MNK1/2-eIF4E axis supports immune suppression and metastasis in postpartum breast c...
https://doi.org/10.1158/0008-5472.CAN-20-3143
Cancer Research; Guo Q, Bartish M et. al.

May 12th, 2021 - Breast cancer diagnosed within 10 years following childbirth is defined as postpartum breast cancer (PPBC) and is highly metastatic. Interactions between immune cells and other stromal cells within the involuting mammary gland are fundamental in f...

Phenotypic heterogeneity and metastasis of breast cancer cells.
https://doi.org/10.1158/0008-5472.CAN-20-1799
Cancer Research; Hapach LA, Carey SP et. al.

May 12th, 2021 - While intratumoral genomic heterogeneity can impede cancer research and treatment, less is known about the effects of phenotypic heterogeneities. To investigate the role of cell migration heterogeneities in metastasis, we phenotypically sorted met...

Breast-Conserving Therapy in Patients with cT3 Breast Cancer with Good Response to Neoa...
https://doi.org/10.1245/s10434-021-09865-4 10.1093/jnci/dji021 10.1200/JCO.2007.15.0235 10.1097/SLA.0000000000000924 10.1002/cncr.25152 10.1200/JCO.2010.31.1258 10.1093/jncimonographs/lgv012 10.1056/NEJMp1205737 10.1001/jamaoncol.2015.1293 10.1016/S0140-6736(13)62422-8 10.1056/NEJMoa1910549 10.1001/jamaoncol.2019.6650 10.1016/S1470-2045(18)30570-9 10.1056/NEJMoa1513750 10.1007/s10549-018-5007-4 10.1016/j.ejca.2010.07.043 10.1200/JCO.2000.18.8.1668 10.1016/j.ijrobp.2007.11.029 10.1097/01.sla.0000197714.14318.6f 10.1038/nrclinonc.2015.63 10.1148/radiol.2017170180 10.1016/j.ejso.2015.01.022 10.1002/bjs.9962 10.1245/s10434-013-2921-x 10.1097/SLA.0000000000000558 10.1245/s10434-018-6404-y 10.1002/bjs.10555 10.1111/j.1365-2559.2006.02419.x 10.1056/NEJMoa0906260 10.1016/j.ijrobp.2013.11.012 10.1097/01.PRS.0000117191.10766.95 10.1007/s10549-006-9325-6 10.1097/MD.0000000000008367 10.1001/jamasurg.2014.2895 10.1111/tbj.12811 10.1016/j.crad.2018.05.026 10.1200/JCO.2011.38.8595 10.1016/j.clinimag.2019.05.006 10.3233/BD-150195 10.1245/s10434-015-4603-3 10.1016/j.jamcollsurg.2007.12.025 10.1245/s10434-009-0402-z 10.1007/BF02573059 10.1016/j.amjsurg.2009.01.006 10.1007/s10549-017-4117-8 10.1007/s10549-009-0616-6 10.1016/j.ejca.2017.05.012 10.1056/NEJMoa022152 10.1056/NEJMoa052122 10.1016/S0140-6736(11)61629-2 10.1200/JCO.2008.19.8424 10.1016/j.radonc.2008.05.002 10.1016/j.ejca.2014.12.003 10.1200/JCO.1997.15.3.963
Annals of Surgical Oncology; van der Noordaa MEM, Ioan I et. al.

May 12th, 2021 - Many cT3 breast cancer patients are treated with mastectomy, regardless of response to neoadjuvant systemic therapy (NST). We evaluated local control of cT3 patients undergoing breast-conserving therapy (BCT) based on magnetic resonance imaging (M...

FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple...
https://doi.org/10.1038/s41467-021-22618-x 10.1186/s12916-019-1326-5 10.1111/tbj.13696 10.1038/s41467-020-19540-z 10.1056/NEJMc1900150 10.6004/jnccn.2020.7554 10.1038/nrc3982 10.1038/s41467-020-19052-w 10.1016/j.bbrc.2009.11.098 10.1126/sciadv.aax8930 10.1038/ncomms12632 10.1038/s41467-020-14794-z 10.1073/pnas.1220425110 10.1371/journal.pone.0200315 10.1016/j.molonc.2009.12.001 10.1038/85339 10.4049/jimmunol.0904020 10.1371/journal.pone.0130126 10.1073/pnas.0405025101 10.1002/eji.200839028 10.1038/cr.2017.90 10.1038/ni967 10.1038/s41389-020-00293-9 10.3892/mmr.2012.1158 10.7150/ijbs.41105 10.1007/s10549-009-0674-9 10.1007/s10549-011-1457-7 10.1186/gb-2010-11-2-r18 10.1186/1471-2164-7-96 10.1002/ijc.28474 10.1073/pnas.1516991112 10.1093/glycob/cwx034 10.1093/glycob/cwl079 10.1016/j.celrep.2017.07.027 10.1186/s13058-017-0904-8 10.1038/s41467-020-17395-y 10.1038/s41467-020-20243-8 10.1038/nchembio.999 10.1016/j.celrep.2017.07.027 10.1074/jbc.M115.679852 10.1007/s11060-009-0038-7 10.1158/1078-0432.CCR-12-0715 10.1200/JCO.20.01974 10.1038/s41591-020-0821-8 10.1080/15548627.2017.1381804 10.1073/pnas.1107385108 10.1245/s10434-014-3564-2 10.1038/s41598-018-25357-0 10.1038/nature11412 10.1093/nar/gky1106
Nature Communications; Huang Y, Zhang HL et. al.

May 12th, 2021 - Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1 immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a highly glycosylated protein. However, the mechanisms of B7H3 glycosylat...

see more →

News  13,639 results

Better Survival After Lumpectomy Plus RT vs Mastectomy
https://www.medscape.com/viewarticle/950803

May 9th, 2021 - Overall survival and breast cancer–specific survival were consistently better for women with early breast cancer who were treated with breast conservation surgery (BCS) followed by radiotherapy (RT) compared to women who were treated with mastecto...

Freezing Breast Cancer to Death Avoids Surgery
https://www.medscape.com/viewarticle/950821

May 9th, 2021 - In the United States, cryoablation or freezing tissue to death is a primary treatment option for a variety of cancers, including those originating in or spread to the bone, cervix, eye, kidney, liver, lung, pancreas, and prostate. Cryoablation for...

COVID Impact on Breast Cancer: Upfront Endocrine Rx Increased
https://www.medscape.com/viewarticle/950624

May 5th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The use of neoadjuvant endocrine therapy (NET) increased significantly during the first 8 months of the COVID-19 pandemic for women with estrogen ...

Breast Cancer Survivors Have Specific Gynecological Needs
https://www.medscape.com/viewarticle/950630

May 5th, 2021 - Sexual dysfunction is a common problem among breast cancer survivors, but it's also an issue inadequately addressed by either ob/gyns. or hematologists and oncologists, according to Erin Keyser, MD, the program director of the San Antonio Uniforme...

Breast Cancer Survivorship Rarely Easy, Even With Early Stage, Low-Risk Disease
https://www.medscape.com/viewarticle/950377

May 3rd, 2021 - NEW YORK (Reuters Health) - Women often have ongoing symptoms and concerns following treatment for early-stage, low-risk breast cancer, according to a new study. "The study findings underscore that survivorship is rarely easy, regardless of the pa...

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Patient Education  283 results see all →