ALLMedicine™ Ductal Carcinoma In Situ Center

Mar 15th, 2023 - Five-year data of the phase III trial TAM-01 showed that low-dose tamoxifen at 5 mg once daily administered for 3 years in women with intraepithelial neoplasia (IEN) reduced by 52% the recurrence of invasive breast cancer or ductal carcinoma in si...

Mar 14th, 2023 - Breast cancer diagnosis had been linked to an increased risk of melanoma in several reports. The aim of the current study was to assess the role of genetics, increased surveillance, and radiation treatment in patients with a dual diagnosis of brea...

Mar 12th, 2023 - The core-needle biopsy (CNB) diagnosis of atypical ductal hyperplasia (ADH) generally mandates follow-up excision, but controversy exists on whether small foci of ADH require surgical management. This study evaluated the upgrade rate at excision o...

Mar 8th, 2023 - Progesterone metabolites 5α-dihydroprogesterone (5αP) and 3α-dihydroprogesterone (3αP) have opposite effects on proliferation, apoptosis and metastasis in the breast. Evidence regarding their influence on ductal carcinoma in situ (DCIS) lesions is...

Mar 8th, 2023 - This study is a prospective observational study involving patients selected for elective bariatric surgery. Thirty-five women older than age 40 and younger than age 74 undergoing primary bariatric surgery and having a BMI of ≥35 will be enrolled i...

May 18th, 2021 - Breast cancer is increasingly prevalent in older adults and is a substantial part of routine oncology practice. However, management of breast cancer in this population is challenging because the disease is highly heterogeneous and there is insuffi...

Jan 14th, 2020 - To update key recommendations of the American Society of Clinical Oncology/College of American Pathologists estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer guideline. A multidisciplinary international Expert Panel w...

Jan 14th, 2020 - To update key recommendations of the American Society of Clinical Oncology/College of American Pathologists estrogen (ER) and progesterone receptor (PgR) testing in breast cancer guideline. A multidisciplinary international Expert Panel was conven...

Aug 17th, 2016 - Controversy exists regarding the optimal negative margin width for ductal carcinoma in situ (DCIS) treated with breast-conserving surgery and whole-breast irradiation. A multidisciplinary consensus panel used a meta-analysis of margin width and ip...

Jul 25th, 2015 - Neoadjuvant systemic therapy is being used increasingly in the treatment of early-stage breast cancer. Response, in the form of pathological complete response, is a validated and evaluable surrogate end point of survival after neoadjuvant therapy....

Mar 8th, 2023 - This study is a prospective observational study involving patients selected for elective bariatric surgery. Thirty-five women older than age 40 and younger than age 74 undergoing primary bariatric surgery and having a BMI of ≥35 will be enrolled i...

Mar 7th, 2023 - A prospective cohort study, conducted in Canada, to prospectively evaluate whether the combination of clinicopathological criteria and the Oncotype DX DCIS score can identify a group of women at very low risk of local recurrence following breast c...

Mar 3rd, 2023 - Cryoablation or tumor freezing is a percutaneous, office-based procedure that is emerging as a minimally invasive, cost-effective alternative to surgery that is currently being evaluated in clinical trials for the management of for early-stage inv...

Feb 27th, 2023 - The study will assess whether changes in kinetic parameters of tumor and peritumoral vasculature using ultrafast dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) during neoadjuvant chemotherapy (NAC) are predictive of pathologic comp...

Feb 9th, 2023 - Twelve women in Denmark are diagnosed with breast cancer every day. Breast cancer and ductal carcinoma in situ (DCIS) are the primary type of cancer/precursor to cancer in women, and one of the main treatment modalities is surgical intervention. D...

Feb 24th, 2023 - Key clinical point: Exposure to ethylene oxide (EtO) emissions (proximity range 10 km) may increase the risk for ductal carcinoma in situ (DCIS) of the breast. Major finding: The presence of EtO-emitting facilities within 10 km was associated with.

Feb 24th, 2023 - Key clinical point: Marking sentinel lymph nodes (SLN) with superparamagnetic iron oxide (SPIO) nanoparticles led to a substantial proportion of patients with ductal carcinoma in situ (DCIS) of the breast avoiding an upfront SLN dissection (SLND).

Dec 20th, 2022 - Key clinical point: Breast conserving surgery (BCS) plus radiotherapy (RT) demonstrated superior survival outcomes compared to mastectomy in patients with ductal carcinoma in situ with microinvasion (DCIS-MI). Major finding: Overall survival (haza.

Dec 19th, 2022 - Key clinical point: The relative risk for anaplastic large cell lymphoma (ALCL) was significantly increased in women who underwent implant reconstruction after mastectomy for breast cancer (BC) or ductal carcinoma in situ. Major finding: The relat.

Nov 18th, 2022 - The study covered in this summary was published on Research Square as a preprint and has not yet been peer reviewed. Key Takeaway Among patients with recurrent or new primary breast cancer, a second breast conserving surgery followed by re-irradia...