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About 89,010 results

ALLMedicine™ Colorectal Cancer Center

Research & Reviews  30,572 results

Bowel Obstruction Due to Stenotic Sigmoid Colon Cancer in a 32-Year-Old Patient Present...
https://doi.org/10.12659/AJCR.935920
The American Journal of Case Reports; Morales Santana DA, Czigany Z et. al.

May 17th, 2022 - BACKGROUND Colorectal cancer among pregnant women is a rare entity. If colon cancer is suspected during pregnancy, the diagnosis is a therapeutic challenge that should be managed by a multidisciplinary team of specialists. Standardized therapeutic...

Oxidized high mobility group B-1 enhances metastability of colorectal cancer via modifi...
https://doi.org/10.1111/cas.15400
Cancer Science; Kishi S, Fujiwara-Tani R et. al.

May 17th, 2022 - High mobility group box-1 (HMGB1) is known to be a chemotactic factor for mesenchymal stem/stromal cells (MSCs), but the effect of post-translational modification on its function is not clear. In this study, we hypothesized that differences in the...

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity a...
https://doi.org/10.1158/0008-5472.CAN-21-0933
Cancer Research; Heinz MC, Peters NA et. al.

May 17th, 2022 - Micrometastases of colorectal cancer can remain dormant for years prior to the formation of actively growing, clinically detectable lesions (i.e., colonization). A better understanding of this step in the metastatic cascade could help improve meta...

Lactobacillus kefiranofaciens JKSP109 and Saccharomyces cerevisiae JKSP39 isolated from...
https://doi.org/10.1039/d1fo02939h
Food & Function; Zeng X, Jia H et. al.

May 17th, 2022 - This study aimed to investigate the alleviative effects of Lactobacillus kefiranofaciens JKSP109 (LK) and Saccharomyces cerevisiae JKSP39 (SC) isolated from Tibetan kefir grain on colon inflammation and colorectal carcinogenesis. Azoxymethane (AOM...

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Guidelines  94 results

ACR Appropriateness Criteria® Staging of Colorectal Cancer: 2021 Update.
https://doi.org/10.1016/j.jacr.2022.02.012
Journal of the American College of Radiology : JACR; , Korngold EK et. al.

May 14th, 2022 - Preoperative imaging of rectal carcinoma involves accurate assessment of the primary tumor as well as distant metastatic disease. Preoperative imaging of nonrectal colon cancer is most beneficial in identifying distant metastases, regardless of pr...

Diagnosis and management of cancer risk in the gastrointestinal hamartomatous polyposis...
https://doi.org/10.1016/j.gie.2022.02.044
Gastrointestinal Endoscopy; Boland CR, Idos GE et. al.

Apr 30th, 2022 - The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis ...

Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis...
https://doi.org/10.1053/j.gastro.2022.02.021
Gastroenterology Boland CR, Idos GE et. al.

Apr 30th, 2022 - The gastrointestinal hamartomatous polyposis syndromes are rare, autosomal dominant disorders associated with an increased risk of benign and malignant intestinal and extraintestinal tumors. They include Peutz-Jeghers syndrome, juvenile polyposis ...

Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recomm...
https://doi.org/10.1001/jama.2022.4983
JAMA , Davidson KW et. al.

Apr 27th, 2022 - Cardiovascular disease (CVD) is the leading cause of mortality in the US, accounting for more than 1 in 4 deaths. Each year, an estimated 605 000 people in the US have a first myocardial infarction and an estimated 610 000 experience a first strok...

Colorectal Cancer Screening — Approach, Evidence, and Future Directions
https://evidence.nejm.org/doi/full/10.1056/EVIDra2100035
NEJM Evidence; Helsingen LM, .

Jan 10th, 2022 - Colorectal cancer is one of the most common cancers worldwide.1 In the United States, 147,000 individuals received a diagnosis of the disease in 2020, and 53,200 died from it.2 Most patients with colorectal cancer are older than 50 years of age at...

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Drugs  113 results see all →

Clinicaltrials.gov  1,435 results

Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers
https://clinicaltrials.gov/ct2/show/NCT04491955

May 13th, 2022 - Background: Metastatic or refractory/recurrent small bowel and colorectal cancers are incurable and poorly palliated by standard therapies. There is an unmet need for active treatments for these tumors. To date immunotherapies including anti PD-1 ...

Phase I/II Trial of the Combination of Bintrafusp Alfa (M7824), Entinostat and NHS-IL12 (M9241) in Patients With Advanced Cancer
https://clinicaltrials.gov/ct2/show/NCT04708470

May 13th, 2022 - Background: Although PD-1(L1) inhibitors have been approved for the treatment of over a dozen different tumor types in recent years, the majority of patients with advanced cancer still do not respond to these agents, including patients with micros...

Clinical and Molecular Study With Digital Support of Patients With Inoperable Lung Cancer
https://clinicaltrials.gov/ct2/show/NCT05372081

May 13th, 2022 - Lung cancer is the primary cause of cancer death worldwide regardless of gender or age group. Based on the most recent statistics for our country, every year about 9000 new cases of lung cancer are diagnosed. Lung cancer is the most common type of...

Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT04941274

May 13th, 2022 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor, caused by Kaposi sarcoma-associated herpesvirus, that most frequently involves the skin, but may also involve lymph nodes, lungs, bone and gastrointestinal tract. It is mo...

Predictors of Physical Activity Maintenance in Colorectal Cancer Survivors
https://clinicaltrials.gov/ct2/show/NCT03781154

May 13th, 2022 - Participants will be prospectively assigned or allocated to either a the exercise intervention or a control group for 12-weeks. The control group will be provided with an informational handout from the American Cancer Society describing exercise r...

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News  3,364 results

Which CRC Regimens Are More Likely to Harm Kidneys?
https://www.medscape.com/viewarticle/974095

May 17th, 2022 - The study was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaways Among the various chemotherapy options for metastatic colorectal cancer (CRC), FOLFIRI + bevacizumab is the most likely to cause acute ki...

Early-Onset Colon Cancer Projected to Double by 2030
https://www.medscape.com/viewarticle/973857

May 12th, 2022 - Early-onset colorectal cancer (CRC) affecting patients younger than 50 years has risen sharply since 1988 from 7.9 to 12.9 cases in 2015 per 100,000 people. The reason for the increase isn’t well understood. The findings were highlighted in a rece...

Real-World Evidence Supports Earlier Colorectal Cancer Screening
https://www.medscape.com/viewarticle/973495

May 5th, 2022 - A new analysis provides much-needed empirical evidence to support recent recommendations from the American Cancer Society and the US Preventive Services Task Force to start colorectal cancer (CRC) screening at age 45. Initiating lower gastrointest...

Tau Moderated by Menopause; CTE Risk Underestimated; When Is a Single Study Enough?
https://www.medpagetoday.com/neurology/generalneurology/98523

May 3rd, 2022 - Menopause status moderated sex differences in tau burden, with a divergence in tauopathy between the sexes apparent 20 years earlier than previously reported. (Annals of Neurology) Plasma p-tau was a less consistent marker of brain amyloidosis in ...

SOT101 Plus Pembrolizumab Elicits Encouraging Efficacy in Advanced Solid Tumors
https://www.onclive.com/view/sot101-plus-pembrolizumab-elicits-encouraging-efficacy-in-advanced-solid-tumors

May 2nd, 2022 - The addition of SOT101, an interleukin (IL)-2/IL-15 Rβγ superagonist, to Pembrolizumab (Keytruda) generated a clinical benefit and encouraging safety data in patients with advanced solid tumors, according to data presented at the 2022 AACR Annual ...

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Patient Education  26 results see all →