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About 49,918 results

ALLMedicine™ Colon Cancer Center

Research & Reviews  23,095 results

Prognostic significance of the expression of metastasis-associated in colon cancer-1 in...
https://doi.org/10.1097/MD.0000000000024255
Medicine Wang L, Fan L et. al.

Mar 5th, 2021 - The prognostic role of the expression of metastasis-associated in colon cancer-1 (MACC1) in gynecologic cancers and breast cancer remains unclear. The aim of this systematic review and meta-analysis was to determine the prognostic significance of ...

FAM3C: an emerging biomarker and potential therapeutic target for cancer.
https://doi.org/10.2217/bmm-2020-0179
Biomarkers in Medicine; Zhu Y, Pu Z et. al.

Mar 5th, 2021 - FAM3C is a member of the FAM3 family. Recently, overexpression of FAM3C has been reported in numerous types of cancer, including breast and colon cancer. Increasing evidence suggests that elevated FAM3C and its altered subcellular localization are...

Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914362
Theranostics Cenigaonandia-Campillo A, Serna-Blasco R et. al.

Mar 5th, 2021 - Background: In hypoxic tumors, positive feedback between oncogenic KRAS and HIF-1α involves impressive metabolic changes correlating with drug resistance and poor prognosis in colorectal cancer. Up to date, designed KRAS-targeting molecules do not...

Evaluating the Effect of Intraoperative Near-Infrared Observation on Anastomotic Leakag...
https://doi.org/10.1097/DCR.0000000000001960
Diseases of the Colon and Rectum; Watanabe J, Ishibe A et. al.

Mar 4th, 2021 - Recent studies have clarified that near-infrared observation using indocyanine green has the advantage of evaluating perfusion of the anastomotic site, especially in rectal cancer surgery, resulting in a reduction in anastomotic leak. The aim of t...

Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in...
https://doi.org/10.1016/j.ejphar.2021.173957
European Journal of Pharmacology; Morii Y, Tsubaki M et. al.

Mar 4th, 2021 - Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutation in colon cancer contributes to the poor prognosis of the disease and chemoresistance of tumors. New therapies are needed; however, the lack of knowledge of th...

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Guidelines  81 results

Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and ...
https://doi.org/10.1016/j.annonc.2020.06.022
Annals of Oncology : Official Journal of the European Soc... Argilés G, Tabernero J et. al.

Jul 23rd, 2020 - Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2020|Argilés G,Tabernero J,Labianca R,Hochhauser D,Salazar R,|diagnosis,epidemiology,therapy,

Alberto F. Sobrero, MD, on Colon Cancer: Adjuvant Oxaliplatin and Fluoropyrimidine-Based Therapy for Stage III Disease
https://ascopost.com/videos/asco20-virtual-scientific-program/alberto-sobrero-on-adjuvant-oxaliplatin-and-fluoropyrimidine-based-therapy-for-stage-iii-colon-cancer/

May 31st, 2020 - Alberto F. Sobrero, MD, of the Ospedale San Martino, discusses final results of the IDEA study, which supported the use of 3 months of adjuvant CAPOX, vs 6 months, for most patients with stage III colon cancer. The shorter treatment duration reduc...

Jeffrey A. Meyerhardt, MD, MPH, on Colon Cancer: Celecoxib and FOLFOX for Stage III Disease
https://ascopost.com/videos/asco20-virtual-scientific-program/jeffrey-meyerhardt-on-celecoxib-and-folfox-for-stage-iii-colon-cancer/

May 29th, 2020 - Jeffrey A. Meyerhardt, MD, MPH, of Dana-Farber Cancer Institute, discusses results from the CALGB/SWOG 80702 trial of celecoxib plus standard adjuvant therapy with fluorouracil, leucovorin, and oxaliplatin (FOLFOX). Adding celecoxib to standard ch...

Final IDEA Collaboration Results Support Just 3 Months of Adjuvant CAPOX for Most Patients With Stage III Colon Cancer
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200177/full/

May 28th, 2020 - Prospective evaluation of nearly 13,000 individuals with stage III colon cancer found minimal difference in 5-year overall survival (OS) with 3 versus 6 months of adjuvant CAPOX or FOLFOX for the majority of patients, according to the final result...

First-Line Win for Anti-PD-1 Drug in Advanced Colon Cancer
https://www.medpagetoday.com/meetingcoverage/asco/86763

May 28th, 2020 - Patients with untreated heavily mutated metastatic colorectal cancer (mCRC) lived twice as long without disease progression when they received an immune checkpoint inhibitor instead of chemotherapy, a randomized trial showed.

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Drugs  135 results see all →

Clinicaltrials.gov  24,949 results

Prognostic significance of the expression of metastasis-associated in colon cancer-1 in...
https://doi.org/10.1097/MD.0000000000024255
Medicine Wang L, Fan L et. al.

Mar 5th, 2021 - The prognostic role of the expression of metastasis-associated in colon cancer-1 (MACC1) in gynecologic cancers and breast cancer remains unclear. The aim of this systematic review and meta-analysis was to determine the prognostic significance of ...

FAM3C: an emerging biomarker and potential therapeutic target for cancer.
https://doi.org/10.2217/bmm-2020-0179
Biomarkers in Medicine; Zhu Y, Pu Z et. al.

Mar 5th, 2021 - FAM3C is a member of the FAM3 family. Recently, overexpression of FAM3C has been reported in numerous types of cancer, including breast and colon cancer. Increasing evidence suggests that elevated FAM3C and its altered subcellular localization are...

Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7914362
Theranostics Cenigaonandia-Campillo A, Serna-Blasco R et. al.

Mar 5th, 2021 - Background: In hypoxic tumors, positive feedback between oncogenic KRAS and HIF-1α involves impressive metabolic changes correlating with drug resistance and poor prognosis in colorectal cancer. Up to date, designed KRAS-targeting molecules do not...

Evaluating the Effect of Intraoperative Near-Infrared Observation on Anastomotic Leakag...
https://doi.org/10.1097/DCR.0000000000001960
Diseases of the Colon and Rectum; Watanabe J, Ishibe A et. al.

Mar 4th, 2021 - Recent studies have clarified that near-infrared observation using indocyanine green has the advantage of evaluating perfusion of the anastomotic site, especially in rectal cancer surgery, resulting in a reduction in anastomotic leak. The aim of t...

Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in...
https://doi.org/10.1016/j.ejphar.2021.173957
European Journal of Pharmacology; Morii Y, Tsubaki M et. al.

Mar 4th, 2021 - Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutation in colon cancer contributes to the poor prognosis of the disease and chemoresistance of tumors. New therapies are needed; however, the lack of knowledge of th...

see more →

News  1,561 results

Differences in Right vs Left Colon in Black vs White Individuals
https://www.medscape.com/viewarticle/943824

Jan 7th, 2021 - The right colon appears to age faster in Black people than in White people, perhaps explaining the higher prevalence of right-side colon cancer among Black Americans, according to results from a biopsy study. The findings were published online Dec...

Surgeon Technical Skill Has Big Impact on Colon Cancer Outcomes
https://www.medscape.com/viewarticle/940538

Nov 8th, 2020 - NEW YORK (Reuters Health) - The technical skills of the surgeon have a considerable impact on patient outcomes followings colon-cancer surgery, according to a new study. "It may seem obvious but it's the first time ever demonstrated - surgeon tech...

Vision Impairment Tied to Less Use of Cancer Screenings by Older Adults
https://www.staging.medscape.com/viewarticle/940183

Nov 2nd, 2020 - (Reuters Health) - Older adults with vision impairment are less likely to receive recommended breast and colon cancer screenings than peers without vision problems, a U.S. study suggests. Researchers examined data from the 2015 and 2018 National H...

Localized Colon Cancer Clinical Practice Guidelines (ESMO, 2020)
https://reference.staging.medscape.com/viewarticle/940055

Nov 2nd, 2020 - The guideline on localized colon cancer was released on October 1, 2020 by the European Society for Medical Oncology.[1] Invasive Screening   A complete colonoscopy is the recommended method for colorectal cancer (CRC) screening in average-risk me...

Localized Colon Cancer Clinical Practice Guidelines (ESMO, 2020)
https://reference.medscape.com/viewarticle/940055

Nov 2nd, 2020 - The guideline on localized colon cancer was released on October 1, 2020 by the European Society for Medical Oncology.[1] Invasive Screening   A complete colonoscopy is the recommended method for colorectal cancer (CRC) screening in average-risk me...

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Patient Education  97 results see all →