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About 652 results

ALLMedicine™ Intestinal Tumors Center

Research & Reviews  325 results

CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signa...
https://doi.org/10.1016/j.canlet.2021.04.012
Cancer Letters; Zhao Q, Guo J et. al.

Apr 24th, 2021 - The excessive release of proinflammatory chemokines promotes cell proliferation and tumor growth in colorectal cancer. However, their regulatory functions and molecular pathogenesis have not been well elucidated. Here, we observed the upregulation...

Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916733
Toxicological Sciences : an Official Journal of the Socie... Chappell GA, Wikoff DS et. al.

Jan 6th, 2021 - Oral exposure to hexavalent chromium (Cr[VI]) induces intestinal tumors in mice. Mutagenic and nonmutagenic modes of action (MOAs) have been accepted by different regulatory bodies globally, the latter involving cytotoxicity-induced regenerative c...

Biological characteristics of IL-6 and related intestinal diseases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757046
International Journal of Biological Sciences; Guo Y, Wang B et. al.

Jan 4th, 2021 - The intestine serves as an important digestive and the largest immune organ in the body. Interleukin-6(IL-6), an important mediator of various pathways, participates in the interactions between different kinds of cells and closely correlates with ...

Sunitinib malate inhibits intestinal tumor development in male ApcMin/+ mice by down-re...
https://doi.org/10.1016/j.intimp.2020.107128
International Immunopharmacology; Chen L, Xu P et. al.

Nov 16th, 2020 - Sunitinib is a tyrosine kinase inhibitor for many tumors. Inflammation is one of the most important factors in the development of intestinal tumors. Many inflammation-related factors are regulated by tyrosine kinase receptors. It is reasonable to ...

PWD/Ph-Encoded Genetic Variants Modulate the Cellular Wnt/β-Catenin Response to Suppres...
https://doi.org/10.1158/0008-5472.CAN-20-1480
Cancer Research; Farrall AL, Lienhard M et. al.

Nov 6th, 2020 - Genetic predisposition affects the penetrance of tumor-initiating mutations, such as APC mutations that stabilize β-catenin and cause intestinal tumors in mice and humans. However, the mechanisms involved in genetically predisposed penetrance are ...

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Clinicaltrials.gov  327 results

CXCL13 promotes intestinal tumorigenesis through the activation of epithelial AKT signa...
https://doi.org/10.1016/j.canlet.2021.04.012
Cancer Letters; Zhao Q, Guo J et. al.

Apr 24th, 2021 - The excessive release of proinflammatory chemokines promotes cell proliferation and tumor growth in colorectal cancer. However, their regulatory functions and molecular pathogenesis have not been well elucidated. Here, we observed the upregulation...

Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916733
Toxicological Sciences : an Official Journal of the Socie... Chappell GA, Wikoff DS et. al.

Jan 6th, 2021 - Oral exposure to hexavalent chromium (Cr[VI]) induces intestinal tumors in mice. Mutagenic and nonmutagenic modes of action (MOAs) have been accepted by different regulatory bodies globally, the latter involving cytotoxicity-induced regenerative c...

Biological characteristics of IL-6 and related intestinal diseases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757046
International Journal of Biological Sciences; Guo Y, Wang B et. al.

Jan 4th, 2021 - The intestine serves as an important digestive and the largest immune organ in the body. Interleukin-6(IL-6), an important mediator of various pathways, participates in the interactions between different kinds of cells and closely correlates with ...

Sunitinib malate inhibits intestinal tumor development in male ApcMin/+ mice by down-re...
https://doi.org/10.1016/j.intimp.2020.107128
International Immunopharmacology; Chen L, Xu P et. al.

Nov 16th, 2020 - Sunitinib is a tyrosine kinase inhibitor for many tumors. Inflammation is one of the most important factors in the development of intestinal tumors. Many inflammation-related factors are regulated by tyrosine kinase receptors. It is reasonable to ...

PWD/Ph-Encoded Genetic Variants Modulate the Cellular Wnt/β-Catenin Response to Suppres...
https://doi.org/10.1158/0008-5472.CAN-20-1480
Cancer Research; Farrall AL, Lienhard M et. al.

Nov 6th, 2020 - Genetic predisposition affects the penetrance of tumor-initiating mutations, such as APC mutations that stabilize β-catenin and cause intestinal tumors in mice and humans. However, the mechanisms involved in genetically predisposed penetrance are ...

see more →