ALLMedicine™ Neuroblastoma Center

Feb 27th, 2021 - Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer with poor prognosis, and there is a critical need for novel therapeutic approaches. NEPC is associated with molecular perturbation of several pathways including ampl...

Feb 26th, 2021 - Objective: Neuroblastoma (NB) is the most common extra-cranial solid tumor in early childhood. Circular RNAs (circRNAs) have been implicated in the development of NB. The purpose of the current study was to explore the molecular action of circRNA ...

Feb 26th, 2021 - In the present study, we have developed the core-shell metal organic framework (MOF) of zinc, wherein titanocene dichloride (TC) loaded lactoferrin (Lf) functioned as a core. The complexation of TC to Lf was studies using molecular dynamics study,...

Feb 25th, 2021 - Olfactory neuroblastoma (ONB) is a rare malignant neuroectodermal tumor. Due to the rarity, there are scarce reports describing the cytological features of ONB. Thus, we aimed to analyze these cytological features and discuss their differences dep...

Feb 25th, 2021 - 18F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) shows tumor activity in most neuroblastomas, but the role of 18F-FDG PET/CT in neuroblastoma remains to be defined. This study explored the prognostic significance of 18F-FDG PET...

May 19th, 2020 - Alice Yu, MD, PhD, of the University of California San Diego School of Medicine, will receive the 2020 Pediatric Oncology Award. The award, first presented in 2002, recognizes a pediatric oncologist who has demonstrated outstanding leadership or a...

Mar 26th, 2015 - Neuroblastoma is the most common extracranial solid tumor in childhood in high-income countries (HIC), where consistent treatment approaches based on clinical and tumor biological risk stratification have steadily improved outcomes. However, in lo...

May 18th, 2011 - Neuroblastoma is an enigmatic disease entity; some tumors disappear spontaneously without any therapy, while others progress with a fatal outcome despite the implementation of maximal modern therapy. However, strong prognostic factors can accurate...

Apr 29th, 2009 - Disseminating disease is a predictive and prognostic indicator of poor outcome in children with neuroblastoma. Its accurate and sensitive assessment can facilitate optimal treatment decisions. The International Neuroblastoma Risk Group (INRG) Task...

Neuroblastoma is the most common extracranial solid tumor in childhood. More than 650 cases are diagnosed each year in the United States.[4,5] The prevalence is about 1 case per 7,000 live births; the incidence is about 10.54 cases per 1 million p...

Feb 27th, 2021 - Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer with poor prognosis, and there is a critical need for novel therapeutic approaches. NEPC is associated with molecular perturbation of several pathways including ampl...

Feb 26th, 2021 - Objective: Neuroblastoma (NB) is the most common extra-cranial solid tumor in early childhood. Circular RNAs (circRNAs) have been implicated in the development of NB. The purpose of the current study was to explore the molecular action of circRNA ...

Feb 26th, 2021 - In the present study, we have developed the core-shell metal organic framework (MOF) of zinc, wherein titanocene dichloride (TC) loaded lactoferrin (Lf) functioned as a core. The complexation of TC to Lf was studies using molecular dynamics study,...

Feb 25th, 2021 - Olfactory neuroblastoma (ONB) is a rare malignant neuroectodermal tumor. Due to the rarity, there are scarce reports describing the cytological features of ONB. Thus, we aimed to analyze these cytological features and discuss their differences dep...

Feb 25th, 2021 - 18F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) shows tumor activity in most neuroblastomas, but the role of 18F-FDG PET/CT in neuroblastoma remains to be defined. This study explored the prognostic significance of 18F-FDG PET...

Nov 30th, 2020 - A novel chimeric antigen receptor (CAR) T-cell therapy developed by researchers at University College London (UCL) to target cancerous tumours has shown promising early results in children with neuroblastoma. In the UCL study, paediatric patients’...

Nov 25th, 2020 - The US Food and Drug Administration (FDA) has granted accelerated approval for a new drug for certain patients with neuroblastoma based on response rate results in small open-label trials. The drug is naxitamab (Danyelza, Y-mAbs Therapeutics), a h...

May 19th, 2020 - Alice Yu, MD, PhD, of the University of California San Diego School of Medicine, will receive the 2020 Pediatric Oncology Award. The award, first presented in 2002, recognizes a pediatric oncologist who has demonstrated outstanding leadership or a...

Mar 26th, 2020 - Neuroblastoma is the most common extracranial solid cancer in childhood and the most common cancer in infancy. It is a neuroendocrine tumor, arising from any neural crest element of the sympathetic nervous system. It most frequently originates in ...

Dec 11th, 2019 - (Reuters Health) - When frozen embryos are used during in vitro fertilization (IVF), the resulting children have a slightly higher risk for certain types of cancer, evidence from Denmark suggests. Analyzing health records of more than a million Da...