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About 3,540 results

ALLMedicine™ Anal Cancer Center

Research & Reviews  1,051 results

Evaluation of dosimetric predictors of toxicity after IMRT with concurrent chemotherapy...
https://doi.org/10.1016/j.radonc.2022.11.018
Radiotherapy and Oncology : Journal of the European Socie... Lukovic J, Hosni A et. al.

Dec 2nd, 2022 - This study investigates the impact of dosimetric parameters on acute and late toxicity for patients with anal squamous cell carcinoma (SCC) treated with image-guided intensity modulated radiation therapy (IG-IMRT) and concurrent chemotherapy. Pati...

Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials: Analysis ...
https://doi.org/10.1097/COC.0000000000000955
American Journal of Clinical Oncology; Kharofa JR, Yothers G et. al.

Nov 23rd, 2022 - Novel toxicity metrics that account for all adverse event (AE) grades and the frequency of may enhance toxicity reporting in clinical trials. The Toxicity Index (TI) accounts for all AE grades and frequencies for categories of interest. We evaluat...

International validation of the EORTC QLQ-ANL27, a field study to test the anal cancer-...
https://doi.org/10.1016/j.ijrobp.2022.11.002
International Journal of Radiation Oncology, Biology, Phy... Sodergren SC, Johnson CD et. al.

Nov 20th, 2022 - The European Organisation for Research and Treatment of Cancer (EORTC) health-related quality of life (HRQoL) questionnaire for anal cancer (QLQ-ANL27) supplements the EORTC cancer generic measure (QLQ-C30) to measure concerns specific to people w...

"The problem is that our culture is just so messed up about aging." Recruiting older me...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9675202
BMC Medical Research Methodology; Hernandez AL, Weatherly CS et. al.

Nov 20th, 2022 - Anal human papillomavirus (HPV) disproportionately affects men who have sex with men (MSM), particularly those who are older and those living with HIV. After experiencing difficulty recruiting older MSM into a study on aging and anal HPV, we condu...

Conventional cytologic diagnosis of human papillomavirus-induced anal intraepithelial n...
https://doi.org/10.1002/dc.25079
Diagnostic Cytopathology; de Barcellos LP, Coutinho JRH et. al.

Nov 19th, 2022 - Screening of anal cancer is rarely available or performed in Brazil. This study analyzes the diagnostic performance of conventional cytology (CC) in the prevention of anal cancer in a coloproctology and gynecology outpatient clinics in a public ho...

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Guidelines  8 results

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT...
https://doi.org/10.1016/j.prro.2022.01.015
Practical Radiation Oncology; Damico N, Meyer J et. al.

Jun 19th, 2022 - Previous anal cancer guidelines delineate target volumes similarly for all patients with squamous cell carcinoma of the anal canal and/or perianal skin (SCCA), regardless of disease stage. The purpose of this guideline is to provide customized rad...

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆.
https://doi.org/10.1016/j.annonc.2021.06.015
Annals of Oncology : Official Journal of the European Soc... Rao S, Guren MG et. al.

Jun 28th, 2021 - Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆.|2021|Rao S,Guren MG,Khan K,Brown G,Renehan AG,|diagnosis,epidemiology,therapy,

Cancer in People Living With HIV, Version 1.2018, NCCN Clinical Practice Guidelines in ...
https://doi.org/10.6004/jnccn.2018.0066
Journal of the National Comprehensive Cancer Network : JN... Reid E, Suneja G et. al.

Aug 14th, 2018 - People living with HIV (PLWH) are diagnosed with cancer at an increased rate over the general population and generally have a higher mortality due to delayed diagnoses, advanced cancer stage, comorbidities, immunosuppression, and cancer treatment ...

Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2018.0060
Journal of the National Comprehensive Cancer Network : JN... Benson AB, Venook AP et. al.

Jul 15th, 2018 - The NCCN Guidelines for Anal Carcinoma provide recommendations for the management of patients with squamous cell carcinoma of the anal canal or perianal region. Primary treatment of anal cancer usually includes chemoradiation, although certain les...

2016 IANS International Guidelines for Practice Standards in the Detection of Anal Canc...
https://doi.org/10.1097/LGT.0000000000000256
Journal of Lower Genital Tract Disease; Hillman RJ, Cuming T et. al.

Aug 26th, 2016 - To define minimum standards for provision of services and clinical practice in the investigation of anal cancer precursors. After initial face to face meetings of experts at the International Papillomavirus meeting in Lisbon, September 17 to 21, 2...

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Drugs  2 results see all →

Clinicaltrials.gov  128 results

NOAC9 - Circulating Tumor DNA Guided Follow-Up in Anal Cancer
https://clinicaltrials.gov/ct2/show/NCT05572801

Oct 10th, 2022 - Squamous cell carcinoma of the anus (SCCA) is a rare disease with less than 200 new cases in Denmark and Sweden each year and approximately 100 new cases in Norway and Finland but with increasing incidence. Primary treatment is chemo-radiotherapy ...

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients
https://clinicaltrials.gov/ct2/show/NCT04444921

Oct 7th, 2022 - PRIMARY OBJECTIVE: I. To demonstrate that anti-PD-1 therapy in combination with carboplatin/weekly paclitaxel results in improved progression-free survival (PFS) versus systemic chemotherapy alone. SECONDARY OBJECTIVES: I. To demonstrate that anti...

Anal Follow-up of Patients With a Gynecological History of High-grade Lesion and More Induced HPV
https://clinicaltrials.gov/ct2/show/NCT05566106

Oct 6th, 2022 - Human Papillomavirus (HPV) infection is the most common sexually transmitted infection in the world. It is currently estimated that 4.5% of all cancers worldwide are attributable to HPV, representing 630,000 new cases per year. HPV is responsible ...

PLAN-A Data- Bio- and Plan- Bank Collection for SCCA in Denmark
https://clinicaltrials.gov/ct2/show/NCT05570279

Oct 6th, 2022 - The study is a prospective registration of treatment related-, toxicity-, Quality of life- and outcome data from patients treated in Denmark with radiotherapy for squamous cell carcinoma of the anus (SCCA), as a cooperation within the Danish Anal ...

Advancing HPV Vaccination Among HIV Positive Adults: The CHAMPS Study
https://clinicaltrials.gov/ct2/show/NCT05065840

Oct 5th, 2022 - People living with HIV (PLWH) are 28 times more likely to be diagnosed with HPV- associated anal cancer than the general population. The HPV vaccine is an effective and safe approach to prevent and reduce the risk of HPV-related disease among PLWH...

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News  205 results

CUE-101 Gets Fast Tracked for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
https://www.onclive.com/view/cue-101-gets-fast-tracked-for-recurrent-metastatic-head-and-neck-squamous-cell-carcinoma

Oct 5th, 2022 - The FDA has granted a fast track designation to CUE-101 for use as a monotherapy and in combination with pembrolizumab (Keytruda) in patients with human papillomavirus (HPV16+) recurrent or metastatic head and neck squamous cell carcinoma (HNSCC)....

Noninvasive Gastric Mapping; Best Foods for the Gut? Lab Score for Crohn's
https://www.medpagetoday.com/gastroenterology/generalgastroenterology/100867

Sep 22nd, 2022 - Could a novel noninvasive gastric mapping device that measures stomach activity offer new insights into chronic nausea and vomiting? (Science Translational Medicine) Vedolizumab (Entyvio) and ustekinumab (Stelara) were both highly effective as thi...

Zanidatamab Zovodotin Showcases Promising Safety, Activity in HER2+ Solid Cancers
https://www.onclive.com/view/zanidatamab-zovodotin-showcases-promising-safety-activity-in-her2-solid-cancers

Sep 21st, 2022 - Zanidatamab zovodotin (ZW49) was found to produce encouraging responses and to have a manageable toxicity profile when used as a monotherapy in heavily pretreated patients with HER2-positive solid cancers, according to data from a first-in-human p...

Exposure to Environmental Carcinogens May Increase Risk for EGFR+ NSCLC
https://www.onclive.com/view/exposure-to-environmental-carcinogens-may-increase-risk-for-egfr-nsclc

Sep 10th, 2022 - Increasing levels of air pollutant particulate matter observed in individuals with exposure to air pollution were associated with an increased risk for the development of EGFR-positive non–small cell lung cancer (NSCLC), according to findings pres...

Tumor Agnostic Role of TMB Biomarker Faces Challenges
https://www.onclive.com/view/tumor-agnostic-role-of-tmb-biomarker-faces-challenges

Aug 18th, 2022 - Although tumor mutational burden burden (TMB) is established as a clinically informative feature of tumors, its optimal use in therapeutic decision-making faces many challenges, and we are only beginning to fully understand its strengths and limit...

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Patient Education  22 results see all →