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About 3,308 results

ALLMedicine™ Anal Cancer Center

Research & Reviews  1,013 results

Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer
https://clinicaltrials.gov/ct2/show/NCT05438836

Aug 4th, 2022 - A single-arm, prospective, Phase II, single-center clinical trial that will investigate if daily online adaptive radiotherapy for anal cancer will significantly reduce early treatment-related GI toxicity compared with the historically reported rat...

DNA Methylation Analysis to predict Regression of high-grade anal Intraepithelial Neopl...
https://doi.org/10.1136/bmjopen-2021-060301
BMJ Open; Dias Gonçalves Lima F, van der Zee RP et. al.

Aug 4th, 2022 - Anal cancer precursors, or high-grade anal intraepithelial neoplasia (HGAIN), are highly prevalent in HIV-seropositive (HIV+) men who have sex with men (MSM). Around 30% of lesions regress within 1 year, but current histopathological assessment is...

Cancer Incidence Among Adults With HIV in a Population-Based Cohort in Korea.
https://doi.org/10.1001/jamanetworkopen.2022.24897
JAMA Network Open; Park B, Ahn KH et. al.

Aug 3rd, 2022 - In combination with a decreased risk of AIDS-defining cancers and improved survival of people infected with HIV, the burden of non-AIDS-defining cancer has increased markedly. Although a substantial number of studies have measured the cancer risk ...

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
https://clinicaltrials.gov/ct2/show/NCT02408861

Aug 2nd, 2022 - PRIMARY OBJECTIVE: I. To demonstrate safety and feasibility of ipilimumab and nivolumab at the standard doses of drug in solid tumor and relapsed refractory HIV-classical Hodgkin lymphoma (cHL) participants with human immunodeficiency virus (HIV) ...

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients
https://clinicaltrials.gov/ct2/show/NCT04444921

Aug 2nd, 2022 - PRIMARY OBJECTIVE: I. To demonstrate that anti-PD-1 therapy in combination with carboplatin/weekly paclitaxel results in improved progression-free survival (PFS) versus systemic chemotherapy alone. SECONDARY OBJECTIVES: I. To demonstrate that anti...

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Guidelines  8 results

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT...
https://doi.org/10.1016/j.prro.2022.01.015
Practical Radiation Oncology; Damico N, Meyer J et. al.

Jun 19th, 2022 - Previous anal cancer guidelines delineate target volumes similarly for all patients with squamous cell carcinoma of the anal canal and/or perianal skin (SCCA), regardless of disease stage. The purpose of this guideline is to provide customized rad...

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆.
https://doi.org/10.1016/j.annonc.2021.06.015
Annals of Oncology : Official Journal of the European Soc... Rao S, Guren MG et. al.

Jun 28th, 2021 - Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆.|2021|Rao S,Guren MG,Khan K,Brown G,Renehan AG,|diagnosis,epidemiology,therapy,

Cancer in People Living With HIV, Version 1.2018, NCCN Clinical Practice Guidelines in ...
https://doi.org/10.6004/jnccn.2018.0066
Journal of the National Comprehensive Cancer Network : JN... Reid E, Suneja G et. al.

Aug 14th, 2018 - People living with HIV (PLWH) are diagnosed with cancer at an increased rate over the general population and generally have a higher mortality due to delayed diagnoses, advanced cancer stage, comorbidities, immunosuppression, and cancer treatment ...

Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
https://doi.org/10.6004/jnccn.2018.0060
Journal of the National Comprehensive Cancer Network : JN... Benson AB, Venook AP et. al.

Jul 15th, 2018 - The NCCN Guidelines for Anal Carcinoma provide recommendations for the management of patients with squamous cell carcinoma of the anal canal or perianal region. Primary treatment of anal cancer usually includes chemoradiation, although certain les...

2016 IANS International Guidelines for Practice Standards in the Detection of Anal Canc...
https://doi.org/10.1097/LGT.0000000000000256
Journal of Lower Genital Tract Disease; Hillman RJ, Cuming T et. al.

Aug 26th, 2016 - To define minimum standards for provision of services and clinical practice in the investigation of anal cancer precursors. After initial face to face meetings of experts at the International Papillomavirus meeting in Lisbon, September 17 to 21, 2...

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Drugs  2 results see all →

Clinicaltrials.gov  125 results

Re-optimization Based Online Adaptive Radiotherapy of Anal Cancer
https://clinicaltrials.gov/ct2/show/NCT05438836

Aug 4th, 2022 - A single-arm, prospective, Phase II, single-center clinical trial that will investigate if daily online adaptive radiotherapy for anal cancer will significantly reduce early treatment-related GI toxicity compared with the historically reported rat...

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients
https://clinicaltrials.gov/ct2/show/NCT04444921

Aug 2nd, 2022 - PRIMARY OBJECTIVE: I. To demonstrate that anti-PD-1 therapy in combination with carboplatin/weekly paclitaxel results in improved progression-free survival (PFS) versus systemic chemotherapy alone. SECONDARY OBJECTIVES: I. To demonstrate that anti...

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
https://clinicaltrials.gov/ct2/show/NCT02408861

Aug 2nd, 2022 - PRIMARY OBJECTIVE: I. To demonstrate safety and feasibility of ipilimumab and nivolumab at the standard doses of drug in solid tumor and relapsed refractory HIV-classical Hodgkin lymphoma (cHL) participants with human immunodeficiency virus (HIV) ...

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study
https://clinicaltrials.gov/ct2/show/NCT04166318

Jul 28th, 2022 - PRIMARY OBJECTIVES: I. To determine whether de-intensified chemoradiation for early stage squamous cell carcinoma of the anal canal (SCCA) is able to maintain excellent 2-year disease control of 85% or higher while improving anorectal health-relat...

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer
https://clinicaltrials.gov/ct2/show/NCT04929028

Jul 27th, 2022 - PRIMARY OBJECTIVES: I. To determine the safety of reduced intensity chemo-radiation therapy (CRT) in low-risk disease. II. To determine the safety of nivolumab after standard CRT in high-risk disease. SECONDARY OBJECTIVES: I. To estimate the effic...

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News  166 results

New Treatment Reduces Risk of Anal Cancer in People With HIV
https://www.medscape.com/viewarticle/975710

Jun 16th, 2022 - It all began with the question, "Has your butt been getting enough attention?" Though that may seem unorthodox, it led researchers to discovering a treatment that may help prevent anal cancer in people with HIV/AIDS. It's still featured on their s...

The benefits of conducting clinical research in private practice
https://www.mdedge.com/gihepnews/article/254038/mixed-topics/benefits-conducting-clinical-research-private-practice
Paul Feuerstadt, MD, FACG, AGAF, Louis Korman, MD, FACG

Apr 25th, 2022 - Most people believe that, if you want to conduct clinical research, the best path is going into academic medicine. However, for physicians who want both the benefits of practicing in the community setting and a career in research, there are many w.

FDA OKs First Condom for Anal Sex
https://www.medscape.com/viewarticle/969174

Feb 25th, 2022 - The first condom specifically designed for use during anal sex has gained FDA approval. Anal intercourse is considered to be much riskier than vaginal sex for the transmission of infections such as HIV and HPV, a risk factor for anal cancer, agenc...

Immunotherapy Outcomes in HPV-Associated Head and Neck Cancer Fuel Investigative Efforts
https://www.onclive.com/view/immunotherapy-outcomes-in-hpv-associated-head-and-neck-cancer-fuel-investigative-efforts

Feb 23rd, 2022 - Promising data from studies evaluating immunotherapy and cellular therapy for patients with head and neck cancers associated with human papilloma virus (HPV) have helped to widen the treatment landscape. However, many clinical questions remain una...

Full Results of Anal Cancer Study Point to Barriers to Care
https://www.medscape.com/viewarticle/968817

Feb 18th, 2022 - Reports based on a press release in October suggested it, but now the full data tell the story: Early monitoring and treatment of anal high-grade squamous intraepithelial lesions (HSIL) cut risk for anal cancer by 57% in people living with HIV. "W...

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Patient Education  9 results see all →