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About 1,345 results

ALLMedicine™ Penile Cancer Center

Research & Reviews  468 results

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease
https://clinicaltrials.gov/ct2/show/NCT00026884

Jun 24th, 2022 - Background Kidney, prostate, bladder, testis and penile cancer account for 22% of cancers diagnosed in the United States and are responsible for 10% of cancer deaths each year in the U.S. Understanding the genes and gene pathways that cause genito...

TIP (Paclitaxel + Ifosfamide + Cisplatin) Combined With Nimotuzumab & Triprilimab as Neoadjuvant Treatment in Locally Advanced Penile Cancer
https://clinicaltrials.gov/ct2/show/NCT04475016

Jun 9th, 2022 - Penile cancer is a rare malignant tumor, which often occurs in the inner plate of prepuce and glans. Squamous cell carcinoma is the most common pathological type. Lymph node metastasis is a crucial factor that leads to poor prognosis of penile can...

Patient reported outcomes in advanced penile cancer.
https://doi.org/10.1016/j.urolonc.2022.04.020
Urologic Oncology; Youssef I, Hoogland AI et. al.

Jun 7th, 2022 - Patient reports of their symptom burden (i.e., patient-reported outcomes or PROs) have been shown to direct clinicians' ability to personalize care and improve outcomes. A disciplined assessment of PRO in the population of patients with advanced p...

When Shall I Ask for a Second Opinion in Specialized Centers and How Can I Find Them? D...
https://doi.org/10.1016/j.soncn.2022.151287
Seminars in Oncology Nursing; Pagliaro LC, Hawk M

Jun 3rd, 2022 - Penile cancer is an uncommon malignancy in the United States and most developed countries, with higher incidence in the developing nations of Africa, Asia, and South America. Standard treatment involves a urologist, medical oncologist, and radiati...

Study of SQZ-eAPC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT05357898

Jun 3rd, 2022 - This is a Phase 1/2, first-in-human, open label, multicenter study to assess safety and tolerability, antitumor activity, and immunogenic and pharmacodynamic effects of SQZ-eAPC-HPV as monotherapy and in combination with pembrolizumab in patients ...

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Guidelines  7 results

Clinical features, molecular characteristics and surgical management of primary penile ...
https://doi.org/10.1097/CMR.0000000000000788
Melanoma Research; Cakir OO, Pozzi E et. al.

Nov 30th, 2021 - Penile mucosal melanoma is an aggressive and rare genital malignancy. The aim of the present study was to review the management and outcomes of a homogenous cohort of patients with histologically confirmed penile mucosal melanoma, at a single spec...

Report From the International Society of Urological Pathology (ISUP) Consultation Confe...
https://doi.org/10.1097/PAS.0000000000001477
The American Journal of Surgical Pathology; Canete-Portillo S, Velazquez EF et. al.

Apr 3rd, 2020 - Penile cancer and its precursor lesions are morphologically and clinically heterogenous and they can be further characterized by immunohistochemical (IHC) and molecular genetic analyses. According to the current World Health Organization (WHO) cla...

EAU guidelines on penile cancer: 2014 update.
https://doi.org/10.1016/j.eururo.2014.10.017
European Urology; Hakenberg OW, Compérat EM et. al.

Dec 3rd, 2014 - Penile cancer has high mortality once metastatic spread has occurred. Local treatment can be mutilating and devastating for the patient. Progress has been made in organ-preserving local treatment, lymph node management, and multimodal treatment of...

Penile cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
https://doi.org/10.1093/annonc/mdt286
Annals of Oncology : Official Journal of the European Soc... Van Poppel H, Watkin NA et. al.

Aug 27th, 2013 - Penile cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2013|Van Poppel H,Watkin NA,Osanto S,Moonen L,Horwich A,|epidemiology,pathology,surgery,therapy,complications,diagnosis,epidemiology,therapy,

New treatment guidelines for penile cancer.
https://doi.org/10.6004/jnccn.2013.0195
Journal of the National Comprehensive Cancer Network : JN... Spiess PE,

Jun 5th, 2013 - Although relatively rare in Western countries, penile cancer is associated with high morbidity and mortality. To achieve the most favorable outcomes in men with this malignancy, early medical or surgical treatment is required. Few data are availab...

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Clinicaltrials.gov  22 results

Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease
https://clinicaltrials.gov/ct2/show/NCT00026884

Jun 24th, 2022 - Background Kidney, prostate, bladder, testis and penile cancer account for 22% of cancers diagnosed in the United States and are responsible for 10% of cancer deaths each year in the U.S. Understanding the genes and gene pathways that cause genito...

TIP (Paclitaxel + Ifosfamide + Cisplatin) Combined With Nimotuzumab & Triprilimab as Neoadjuvant Treatment in Locally Advanced Penile Cancer
https://clinicaltrials.gov/ct2/show/NCT04475016

Jun 9th, 2022 - Penile cancer is a rare malignant tumor, which often occurs in the inner plate of prepuce and glans. Squamous cell carcinoma is the most common pathological type. Lymph node metastasis is a crucial factor that leads to poor prognosis of penile can...

Study of SQZ-eAPC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT05357898

Jun 3rd, 2022 - This is a Phase 1/2, first-in-human, open label, multicenter study to assess safety and tolerability, antitumor activity, and immunogenic and pharmacodynamic effects of SQZ-eAPC-HPV as monotherapy and in combination with pembrolizumab in patients ...

An Investigational Immuno-therapy Study to Investigate the Safety and Effectiveness of Nivolumab, and Nivolumab Combination Therapy in Virus-associated Tumors
https://clinicaltrials.gov/ct2/show/NCT02488759

May 25th, 2022 - The purpose of this study to investigate the safety and effectiveness of nivolumab, and nivolumab combination therapy, to treat patients who have virus-associated tumors. Certain viruses have been known to play a role in tumor formation and growth...

Complications and Adverse Events in Lymphadenectomy in the Inguinal Area
https://clinicaltrials.gov/ct2/show/NCT05388786

May 24th, 2022 - Inguinal lymph node dissection (ILND) has shown to be a necessary surgery from the oncology standpoint being extensively used as part of the staging process in malignancies of the penis, vulva, or melanoma. Moreover, the ILND has been shown to imp...

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News  39 results

Leiomyosarcoma of the Penis: A Case Report and Re-Appraisal
https://www.mdedge.com/fedprac/article/254639/oncology/leiomyosarcoma-penis-case-report-and-re-appraisal
Zainub Ajmal, MBBS, Abdul Moiz Khan, MBBS et. al.

May 16th, 2022 - Penile cancer is rare with a worldwide incidence of 0. 8 cases per 100,000 men.

Atezolizumab Fails to Meet PFS End Point in Advanced Penile Squamous Cell Carcinoma
https://www.onclive.com/view/atezolizumab-fails-to-meet-pfs-end-point-in-advanced-penile-squamous-cell-carcinoma

Feb 21st, 2022 - Atezolizumab (Tecentriq) with or without radiotherapy did not demonstrate efficacy in patients with advanced squamous cell carcinoma of the penis, according to results from the phase 2 PERICLES trial (NCT03686332) presented at the 2022 American So...

Immunotherapy Trials Offer Hope in Advanced Penile Cancer
https://www.onclive.com/view/immunotherapy-trials-offer-hope-in-advanced-penile-cancer

Oct 6th, 2021 - Guru Sonpavde, MD Penile cancer is a historically poor-prognosis disease, with patients who progress following chemotherapy having little to no effective options. This needs to change, says Guru Sonpavde, MD, starting with replacing the standard ...

Dr. Sonpavde on the Potential for Immunotherapy in Penile Cancer
https://www.onclive.com/view/dr-sonpavde-on-the-potential-for-immunotherapy-in-penile-cancer

Oct 6th, 2021 - Guru Sonpavde, MD, director of Bladder Cancer at the Dana-Farber Cancer Institute, discusses the potential for immunotherapy in penile cancer. There is promise for PD-1 checkpoint inhibitors, as well as CTLA-4 plus PD-L1 combination strategies in...

Cervical cancer rates fall, but other HPV cancers increase
https://www.mdedge.com/hematology-oncology/article/240432/gynecologic-cancer/cervical-cancer-rates-fall-other-hpv-cancers
Sharon Worcester

May 21st, 2021 - Cervical cancer incidence in the United States decreased by about 1% per year from 2001 to 2017, but at the same time there was an increase in the incidence of other human papillomavirus (HPV)–related cancers, a new study reveals. Over the same pe.

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Patient Education  2 results see all →