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About 1,341 results

ALLMedicine™ Mucosal Melanoma Center

Research & Reviews  661 results

Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036556
International Journal of Environmental Research and Publi... Bondi S, Vinciguerra A et. al.

Apr 3rd, 2021 - Mucosal melanomas of the head and neck region are uncommon pathologies that can affect the oral cavity, and are characterized by a high rate of mortality. Considering the lack of knowledge regarding risk and prognostic factors, current best clinic...

CDK4 and TERT amplification in head and neck mucosal melanoma.
https://doi.org/10.1111/jop.13180
Journal of Oral Pathology & Medicine : Official Publicati... Lyu J, Miao Y et. al.

Apr 2nd, 2021 - Recent high-throughput sequencing studies have revealed frequent CDK4 and TERT amplification in mucosal melanoma, suggesting that they are potential therapeutic targets. In this study, we investigated the statuses of CDK4 and TERT in head and neck...

Immunotherapy combined with high- and low-dose radiation to all sites leads to complete...
https://doi.org/10.1016/j.ygyno.2021.03.017
Gynecologic Oncology; Sezen D, Patel RR et. al.

Apr 2nd, 2021 - A 73-year-old woman with metastatic vaginal mucosal melanoma that had progressed on ipilimumab and nivolumab experienced clinical and radiographic complete response to dual checkpoint inhibitor immunotherapy given in combination with high-dose plu...

Prognostic value and therapeutic implications of nodal involvement in head and neck muc...
https://doi.org/10.1002/hed.26694
Head & Neck; Moya-Plana A, Mangin D et. al.

Mar 30th, 2021 - The prognostic significance of nodal involvement is not well established in head and neck mucosal melanoma (HNMM). A retrospective, monocentric study was performed on 96 patients with HNMM treated between 2000 and 2017. At diagnosis, seventeen pat...

Dasatinib stimulates its own mechanism of resistance by activating a CRTC3/MITF/Bcl-2 p...
https://doi.org/10.1158/1541-7786.MCR-20-1040
Molecular Cancer Research : MCR; Sabbah M, Krayem M et. al.

Mar 20th, 2021 - Amplification or activating mutations of c-Kit are a frequent oncogenic alteration that occurs commonly in acral and mucosal melanoma. Among c-Kit inhibitors, dasatinib is the most active due to its ability to bind both active and inactive conform...

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Guidelines  2 results

Ano-uro-genital mucosal melanoma UK national guidelines.
https://doi.org/10.1016/j.ejca.2020.04.030
European Journal of Cancer (Oxford, England : 1990); Smith HG, Bagwan I et. al.

Jun 12th, 2020 - Ano-uro-genital (AUG) mucosal melanomas are rare cancers associated with poor outcomes and limited evidence-based management. The United Kingdom AUG mucosal melanoma guideline development group used an evidence-based systematic approach to make re...

Mucosal melanoma of the head and neck.
https://doi.org/10.6004/jnccn.2012.0033
Journal of the National Comprehensive Cancer Network : JN... Pfister DG, Ang KK et. al.

Mar 6th, 2012 - Mucosal melanoma of the head and neck.|2012|Pfister DG,Ang KK,Brizel DM,Burtness B,Cmelak AJ,|diagnosis,therapy,diagnosis,therapy,pathology,

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Clinicaltrials.gov  673 results

Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036556
International Journal of Environmental Research and Publi... Bondi S, Vinciguerra A et. al.

Apr 3rd, 2021 - Mucosal melanomas of the head and neck region are uncommon pathologies that can affect the oral cavity, and are characterized by a high rate of mortality. Considering the lack of knowledge regarding risk and prognostic factors, current best clinic...

CDK4 and TERT amplification in head and neck mucosal melanoma.
https://doi.org/10.1111/jop.13180
Journal of Oral Pathology & Medicine : Official Publicati... Lyu J, Miao Y et. al.

Apr 2nd, 2021 - Recent high-throughput sequencing studies have revealed frequent CDK4 and TERT amplification in mucosal melanoma, suggesting that they are potential therapeutic targets. In this study, we investigated the statuses of CDK4 and TERT in head and neck...

Immunotherapy combined with high- and low-dose radiation to all sites leads to complete...
https://doi.org/10.1016/j.ygyno.2021.03.017
Gynecologic Oncology; Sezen D, Patel RR et. al.

Apr 2nd, 2021 - A 73-year-old woman with metastatic vaginal mucosal melanoma that had progressed on ipilimumab and nivolumab experienced clinical and radiographic complete response to dual checkpoint inhibitor immunotherapy given in combination with high-dose plu...

Prognostic value and therapeutic implications of nodal involvement in head and neck muc...
https://doi.org/10.1002/hed.26694
Head & Neck; Moya-Plana A, Mangin D et. al.

Mar 30th, 2021 - The prognostic significance of nodal involvement is not well established in head and neck mucosal melanoma (HNMM). A retrospective, monocentric study was performed on 96 patients with HNMM treated between 2000 and 2017. At diagnosis, seventeen pat...

Dasatinib stimulates its own mechanism of resistance by activating a CRTC3/MITF/Bcl-2 p...
https://doi.org/10.1158/1541-7786.MCR-20-1040
Molecular Cancer Research : MCR; Sabbah M, Krayem M et. al.

Mar 20th, 2021 - Amplification or activating mutations of c-Kit are a frequent oncogenic alteration that occurs commonly in acral and mucosal melanoma. Among c-Kit inhibitors, dasatinib is the most active due to its ability to bind both active and inactive conform...

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News  5 results

Rare Melanomas Prove 'Hard to Get' Using Immunotherapy
https://www.staging.medscape.com/viewarticle/877064

Mar 12th, 2017 - Hello. This is Dr Jeffrey Weber. I am a medical oncologist at the Perlmutter Cancer Center at the New York University Langone Medical Center in New York. Today we are going to be talking about the use of immunotherapy in some of the more unusual m...

Rare Melanomas Prove 'Hard to Get' Using Immunotherapy
https://www.medscape.com/viewarticle/877064

Mar 12th, 2017 - Hello. This is Dr Jeffrey Weber. I am a medical oncologist at the Perlmutter Cancer Center at the New York University Langone Medical Center in New York. Today we are going to be talking about the use of immunotherapy in some of the more unusual m...

Dismal Outcomes Seen in Mucosal Melanoma
https://www.mdedge.com/familymedicine/article/25159/dermatology/dismal-outcomes-seen-mucosal-melanoma
Family Practice News; Jeff Evans

WASHINGTON — Older age and disease location appear to contribute to the generally poor prognosis of patients who have mucosal melanoma, according to two retrospective studies reported at the Sixth International Conference on Head and Neck Cancer.

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