About 615 results

ALLMedicine™ Oral Leukoplakia Center

Research & Reviews  238 results

Recurrent copy number alterations involving EGFR, CDKN2A, and CCND1 in oral premalignan...
Journal of Oral Pathology & Medicine : Official Publicati... Jäwert F, Fehr A et. al.

May 1st, 2022 - A major challenge in the management of patients with oral leukoplakia (OL) is the difficulty to identify patients at high risk of developing oral squamous cell carcinomas (OSCC). Our knowledge about genomic alterations in OL, and in particular in ...

Mucoadhesive Nucleoside-Based Hydrogel Delays Oral Leukoplakia Canceration.
Journal of Dental Research; Ding T, Zou J et. al.

Apr 2nd, 2022 - Some oral squamous cell carcinomas (OSCCs) originate from preexisting oral potentially malignant disorders (OPMDs). Oral leukoplakia (OLK) is the most common and typical OPMD in the clinic, so treatment for it is essential to reduce OSCC incidence...

Can tissue biomarkers be used to determine the prognosis of oral leukoplakia lesions wi...
Evidence-based Dentistry; Cousins M, Carney K

Mar 27th, 2022 - Design Systematic review looking at published studies which aimed to identify human tissue biomarkers which could predict malignant transformation of oral leukoplakia (OL) lesions.Case/control selection Articles were identified from PubMed, EBSCO ...

Dermatologic Manifestations of Oral Leukoplakia Treatment & Management

Mar 10th, 2022 - Medical Care The objective of care is to detect and to prevent malignant change. The presence of the white plaque alone does not require treatment. Possible courses of action include the following: Remove any precipitating factors Medical therapie...

see more →

Clinicaltrials.gov  4 results

A Randomized Study of Sulindac in Oral Premalignant Lesions

Nov 19th, 2020 - Oral precancerous lesions (OPL) represent a valuable model for clinical trials for tobacco related cancers. However, due to the relatively low prevalence of this condition in the United States, subject accrual to such trials is slow. Conversely, i...

8-Hydroxy-2-Deoxyguanosine ,Total Antioxidant Capacity in Oral Premalignant and Malignant Lesions

Feb 20th, 2019 - Detection of molecular markers in saliva is superior to their detection in serum and other body fluids due to the fact of being an easy non-invasive tool requiring no training for its collection. Consequently, the aim of our work was to investigat...

Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia

Jul 28th, 2017 - The purpose of this research was to determine the effectiveness of two high-power ablative lasers in the treatment of oral leukoplakia. Furthermore, the purpose was to compare reciprocally and evaluate the subjective and objective postoperative pa...

Aspirin Mouthwash in Treating Patients With Oral Leukoplakia

Aug 12th, 2013 - OBJECTIVES: To determine if oral topical acetylsalicylic acid mouthwash achieves modulation of COX-1, COX-2, and prostaglandin in oral dysplasia tissues in patients with oral leukoplakia. To determine if this drug achieves alteration of histopatho...

see more →

News  4 results

Tylosis in a Patient With Howel-Evans Syndrome: Management With Acitretin
Sabra M. Abner, MD, Audra Isaac, MD et. al.

Nov 4th, 2020 - To the Editor: Tylosis with esophageal cancer was first described by Howel-Evans et al1 in 1958 in a family from Liverpool, England. The disease is inherited in an autosomal-dominant fashion with a mutation in the tylosis with esophageal cancer ge.

Management Strategies for Oral Potentially Malignant Disorders

Mar 16th, 2018 - Oral Potentially Malignant Disorders Oral potentially malignant disorders (OPMDs) include oral leukoplakia (OL), oral erythroplakia, oral submucous fibrosis, oral lichen planus, proliferative verrucous leukoplakia, and actinic keratosis. Once an O...

AACR: Less Cancer With NSAIDs But More Cardiovascular Deaths

Apr 18th, 2005 - Action Points This preliminary study suggests that NSAIDs reduce the risk of oral cancer. However, advise patients who inquire about these findings that this may place them at increased risk of death from heart disease. Advise smokers that smoking...

Black hairy tongue
Sergio Vañó-Galván, MD, Pedro Jaén, PhD

A 71-year-old man presents for evaluation of an asymptomatic black discoloration of the tongue that he noticed several days earlier. The tongue does not itch or hurt, and the patient is otherwise well, although he is concerned about potential mali.

see more →