About 78,468 results

ALLMedicine™ Squamous Cell Carcinoma Center

Research & Reviews  27,232 results

A systematic review of neoadjuvant and definitive immunotherapy in locally advanced hea...
Cancer Medicine; Nindra U, Hurwitz J et. al.

Mar 20th, 2023 - Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) require multi-modality treatment. Immune checkpoint inhibitors (ICIs) are now standard of care in management of recurrent/metastatic HNSCC. However, its role in the defin...

High Expression Level of BRD4 Is Associated with a Poor Prognosis and Immune Infiltrati...
Digestive Diseases and Sciences; Li L, Gao L et. al.

Mar 19th, 2023 - Bromodomain-containing protein 4 (BRD4) is a reader of histone acetylation and is associated with a variety of diseases. To investigate the expression level of BRD4 in esophageal squamous cell carcinoma (ESCC), its prognostic value and its relatio...

H3K27me3 Inactivates SFRP1 to Promote Cell Proliferation via Wnt/β-Catenin Signaling Pa...
Digestive Diseases and Sciences; Zhou M, Yu S et. al.

Mar 19th, 2023 - Histone methylations are generally considered to play an important role in multiple cancers by regulating cancer-related genes. This study aims to investigate the effects of H3K27me3-mediated inactivation of tumor suppressor gene SFRP1 and its fun...

Top 10 Clear Cell Head and Neck Lesions to Contemplate.
Head and Neck Pathology; Cipriani NA, Kakkar A

Mar 18th, 2023 - Optically clear cytoplasm may occur in neoplastic and non-neoplastic conditions, either as a characteristic feature of a disease entity or as a morphologic rarity, potentially creating diagnostic dilemmas in various organ systems. In the head and ...

Robot-assisted thoracic surgery for stages IIB-IVA non-small cell lung cancer: retrospe...
Journal of Robotic Surgery; Shahin GMM, Vos PWK et. al.

Mar 18th, 2023 - Robot-assisted thoracic surgery (RATS) for higher stages non-small cell lung carcinoma (NSCLC) remains controversial. This study reports the feasibility of RATS in patients with stages IIB-IVA NSCLC. A single-institute, retrospective study was con...

see more →

Guidelines  39 results

Immunotherapy and Biomarker Testing in Recurrent and Metastatic Head and Neck Cancers: ...
Journal of Clinical Oncology : Official Journal of the Am... Yilmaz E, Ismaila N et. al.

Dec 16th, 2022 - To provide evidence-based recommendations for practicing physicians and other health care providers on immunotherapy and biomarker testing for head and neck cancers. ASCO convened an Expert Panel of medical oncology, surgical oncology, radiation o...

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT...
Practical Radiation Oncology; Damico N, Meyer J et. al.

Jun 19th, 2022 - Previous anal cancer guidelines delineate target volumes similarly for all patients with squamous cell carcinoma of the anal canal and/or perianal skin (SCCA), regardless of disease stage. The purpose of this guideline is to provide customized rad...

Clinical features, molecular characteristics and surgical management of primary penile ...
Melanoma Research; Cakir OO, Pozzi E et. al.

Nov 30th, 2021 - Penile mucosal melanoma is an aggressive and rare genital malignancy. The aim of the present study was to review the management and outcomes of a homogenous cohort of patients with histologically confirmed penile mucosal melanoma, at a single spec...

Poor tumor differentiation is an independent adverse prognostic variable in patients wi...
Cancer Medicine; Lee LY, Lin CY et. al.

Sep 18th, 2021 - We sought to compare the prognostic impact of tumor differentiation with respect to adverse risk factors (RFs) identified by the National Comprehensive Cancer Network (NCCN) guidelines--including extranodal extension (ENE), positive/close margins,...

ACR Appropriateness Criteria® Staging and Follow-up of Vulvar Cancer.
Journal of the American College of Radiology : JACR; , Lakhman Y et. al.

May 8th, 2021 - Vulvar cancer is an uncommon gynecologic tumor and one of several human papillomavirus-associated malignancies. Squamous cell carcinoma is the most prevalent histologic subtype of vulvar cancer, accounting for the majority of cases. Imaging plays ...

see more →

Drugs  77 results see all →

Clinicaltrials.gov  1,939 results

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

Mar 10th, 2023 - Study Description: Individuals undergoing cisplatin-based chemoradiation therapy are at risk for developing significant, permanent hearing loss. The cholesterol-lowering drug atorvastatin has the potential to reduce the incidence and severity of h...

5-Azacytidine and/or Nivolumab in Resectable HPV-Associated HNSCC

Mar 10th, 2023 - This Phase 0 study is a 3-arm window trial, randomizing patients to pre-operative treatment with 5-azacytidine alone, to nivolumab alone, or the combination of 5-azacytidine and nivolumab. The primary endpoint is immune-related pathologic response...

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Added to Radiation or Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent H...

Mar 10th, 2023 - PRIMARY OBJECTIVES: I. To evaluate overall survival (OS) of adjuvant reirradiation plus concurrent pembrolizumab followed by pembrolizumab to complete 12 months total of pembrolizumab to adjuvant reirradiation plus concurrent platinum chemotherapy...

Ph II Long Term/Low Dose Xeloda in Head and Neck Squamous Cell Carcinoma After Surgery, Radiation & or Chemo

Mar 10th, 2023 - OBJECTIVES: Primary Determine the feasibility of adjuvant low-dose capecitabine in patients with squamous cell carcinoma of the head and neck who have undergone prior curative surgery, radiotherapy, and/or chemotherapy. Secondary Determine the tim...

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

Mar 10th, 2023 - PRIMARY OBJECTIVES: I. To evaluate the disease-free survival (DFS) of patients with stage III-IV squamous cell carcinoma of the head and neck (SCCHN) and disruptive p53 mutations after primary surgical resection followed by postoperative radiother...

see more →

News  2,039 results

Jimmy Carter's Melanoma; Post-Op Osimertinib Boosts OS; $83K for Unproven Therapy

Mar 9th, 2023 - How the successful use of pembrolizumab (Keytruda) for former President Jimmy Carter's metastatic melanoma put "immunotherapy on the map." (Washington Post) A study of molecular changes observed in the breast tissue of transgender men undergoing a...

Epithelioma Cuniculatum (Plantar Verrucous Carcinoma): A Systematic Review of Treatment Options
Samantha Shwe Daniel, MD, MBA, Surget V. Cox, MD et. al.

Mar 2nd, 2023 - Verrucous carcinoma (VC) is an uncommon type of well-differentiated squamous cell carcinoma (SCC) that most commonly affects men in the fifth to sixth decades of life. 1 The tumor grows slowly over a decade or more and does not frequently metastas.

Complaints of cough and fatigue

Feb 28th, 2023 - The history and findings in this case are suggestive of non–small cell lung cancer (NSCLC) large cell carcinoma. Lung cancer is the most common cancer worldwide and has the highest mortality rate of all cancers.

Complaints of cough and fatigue

Feb 28th, 2023 - The history and findings in this case are suggestive of non–small cell lung cancer (NSCLC) large cell carcinoma. Lung cancer is the most common cancer worldwide and has the highest mortality rate of all cancers.

Complaints of cough and fatigue

Feb 28th, 2023 - The history and findings in this case are suggestive of non–small cell lung cancer (NSCLC) large cell carcinoma. Lung cancer is the most common cancer worldwide and has the highest mortality rate of all cancers.

see more →

Patient Education  61 results see all →