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About 22,758 results

ALLMedicine™ Thyroid Cancer Center

Research & Reviews  7,408 results

ELANE neutropenia and solid tumors: Four cases from the French severe chronic neutropen...
https://doi.org/10.1002/pbc.29923
Pediatric Blood & Cancer; Donadieu J, Bou Mitri F et. al.

Aug 16th, 2022 - Neutropenia related to ELANE gene mutations predisposes patients to infection and leukemia/myelodysplasia, but little is known about the predisposition to cancer. Among a cohort of 147 patients, we identified four with malignant solid tumors (papi...

SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and I...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365581
Disease Markers; Zhou X, Lin L et. al.

Aug 16th, 2022 - Thyroid carcinoma (TC) is an increasingly common malignancy of endocrine organs, and its most frequently encountered histotype is papillary thyroid cancer (PTC). Identifying new potential gene alterations is important for completely elucidating th...

Pan-cancer efficacy of pralsetinib in patients with RET fusion-positive solid tumors fr...
https://doi.org/10.1038/s41591-022-01931-y
Nature Medicine; Subbiah V, Cassier PA et. al.

Aug 13th, 2022 - Oncogenic RET fusions occur in diverse cancers. Pralsetinib is a potent, selective inhibitor of RET receptor tyrosine kinase. ARROW ( NCT03037385 , ongoing) was designed to evaluate pralsetinib efficacy and safety in patients with advanced RET-alt...

Tumor mutation burden-assisted risk stratification for papillary thyroid cancer.
https://doi.org/10.1007/s12020-022-03154-0
Endocrine Chen Z, Wang W et. al.

Aug 13th, 2022 - Although papillary thyroid cancer (PTC) has a low mortality rate, the rate of recurrence remains relatively high. This study aims to develop a molecular signature to predict the recurrence of PTC. A total of 333 PTC patients' data from The Cancer ...

Dabrafenib and Lapatinib in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by Surgery
https://clinicaltrials.gov/ct2/show/NCT01947023

Aug 12th, 2022 - PRIMARY OBJECTIVE: I. To determine the maximum tolerated dose of lapatinib that can be used in combination of dabrafenib. SECONDARY OBJECTIVES: I. To observe and record anti-tumor activity. II. Evaluate potential mechanisms of primary resistance o...

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Guidelines  26 results

ESMO Clinical Practice Guideline update on the use of systemic therapy in advanced thyr...
https://doi.org/10.1016/j.annonc.2022.04.009
Annals of Oncology : Official Journal of the European Soc... Filetti S, Durante C et. al.

May 2nd, 2022 - ESMO Clinical Practice Guideline update on the use of systemic therapy in advanced thyroid cancer.|2022|Filetti S,Durante C,Hartl DM,Leboulleux S,Locati LD,|drug therapy,

A Joint Statement from the American Thyroid Association, the European Association of Nu...
https://doi.org/10.1089/thy.2020.0826
Thyroid : Official Journal of the American Thyroid Associ... Gulec SA, Ahuja S et. al.

Apr 2nd, 2021 - Background: The American Thyroid Association (ATA), the European Association of Nuclear Medicine, the European Thyroid Association, and the Society of Nuclear Medicine and Molecular Imaging have established an intersocietal working group to addres...

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349723
Thyroid : Official Journal of the American Thyroid Associ... Bible KC, Kebebew E et. al.

Mar 18th, 2021 - Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Since the guidelines for the management of ATC by the American Thyroid Association were first published in 2012, significant clinical and scientific ad...

The revised clinical practice guidelines on the management of thyroid tumors by the Jap...
https://doi.org/10.1507/endocrj.EJ20-0025
Endocrine Journal; Ito Y, Onoda N et. al.

Apr 10th, 2020 - The Japan Associations of Endocrine Surgeons has developed the revised version of the Clinical Practice Guidelines for Thyroid Tumors. This article describes the guidelines translated into English for the 35 clinical questions relevant to the ther...

African Head and Neck Society Clinical Practice guidelines for thyroid nodules and canc...
https://doi.org/10.1002/hed.26094
Head & Neck; Zafereo M, Yu J et. al.

Mar 8th, 2020 - International thyroid nodule and cancer management guidelines generally fail to take into account potential limitations in diagnostic and treatment resources. Thyroid cancer specialists from the African Head and Neck Society and American Head & Ne...

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Drugs  226 results see all →

Clinicaltrials.gov  498 results

Cancer and Blood Pressure Management, CARISMA Study
https://clinicaltrials.gov/ct2/show/NCT04467021

Aug 12th, 2022 - PRIMARY OBJECTIVE: I. To determine the feasibility of an intensive (systolic blood pressure [SBP] < 120 mmHg) "Intervention" versus standard care (SBP < 140 mmHg) "Non-Intervention" approach to blood pressure (BP) control in metastatic renal cell ...

Dabrafenib and Lapatinib in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by Surgery
https://clinicaltrials.gov/ct2/show/NCT01947023

Aug 12th, 2022 - PRIMARY OBJECTIVE: I. To determine the maximum tolerated dose of lapatinib that can be used in combination of dabrafenib. SECONDARY OBJECTIVES: I. To observe and record anti-tumor activity. II. Evaluate potential mechanisms of primary resistance o...

Long Period Observation of Biochemical Survey and Ultrasonography in Thyroid Diseases and Subclinical Thyroid Diseases
https://clinicaltrials.gov/ct2/show/NCT02868476

Aug 12th, 2022 - Clinical and subclinical thyroid disease is usually used to describe patients with mild symptoms correlated to hyperthyroid or hypothyroid state. Thyroid ultrasonography could differentiate benign or malignant nodular lesion, together with fine ne...

A Study of Pralsetinib Versus Standard of Care (SOC) for Treatment of RET-Mutated Medullary Thyroid Cancer (MTC).
https://clinicaltrials.gov/ct2/show/NCT04760288

Aug 11th, 2022 - A study to evaluate the efficacy and safety of pralsetinib compared with SOC treatment (cabozantinib or vandetanib) for participants with RET (rearranged during transfection)-mutant MTC who have not previously received a SOC MultiKinase Inhibitor ...

A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer
https://clinicaltrials.gov/ct2/show/NCT04211337

Aug 9th, 2022 - Adaptive sample size re-estimation will be performed at interim analysis. The sample size could be increased from approximately 250 to 400 depending on the results of interim analysis.

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News  935 results

Can a Fitbit or Apple Watch Help Fight Thyroid Disease?
https://www.medscape.com/viewarticle/976969

Jul 21st, 2022 - A nursing student recently used a TikTok video that went viral to share how she believed that her Apple Watch could have helped diagnose her thyroid condition. Noting that such wearable devices can track oxygen levels, heart rate, presence of irre...

Thyroid Nodule Surgeries Find Cancer in 46% of Cases
https://www.medscape.com/viewarticle/977490

Jul 19th, 2022 - As many as 40% of thyroid nodule surgeries involve nodules that are asymptomatic. These nodules are often detected by chance during imaging for other purposes, new research shows. Cancer was found only in 46% of these cases. "The results of this s...

Is Long-Term Antithyroid Use the Best Treatment for Graves Disease?
https://www.medscape.com/viewarticle/973869

Jul 7th, 2022 - This transcript has been edited for clarity. Angela Leung, MD, MSc: Welcome to this video commentary about the long-term use of antithyroid drugs in the management of Graves disease. My name is Angela Leung. I'm an adult endocrinologist at the Uni...

Dabrafenib-Trametinib Combo Approved for Range of Solid Tumors
https://www.medscape.com/viewarticle/976117

Jun 23rd, 2022 - The US Food and Drug Administration has granted accelerated approval to dabrafenib (Tafinlar) plus trametinib (Mekinist) for adult and pediatric patients aged 6 years and older with unresectable or metastatic solid tumors with the BRAF V600E mutat...

Harry Potter's World Offers View Into Magic of Endocrinology
https://www.medscape.com/viewarticle/975847

Jun 22nd, 2022 - Clinicians don't cease diagnosing patients once our clinical work is done. Most of us can recall debating whether to point out an atypical mole or another concerning finding to a stranger in public. Like the doctor back in 2018, who saw a lump on ...

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Patient Education  10 results see all →