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About 36,997 results

ALLMedicine™ Acute Lymphoblastic Leukemia Center

Research & Reviews  17,243 results

Preventing weight gain in children with acute lymphoblastic leukemia by early nutrition...
https://doi.org/10.1002/pbc.28965
Pediatric Blood & Cancer; Browne EK, Inaba H

Feb 24th, 2021 - Preventing weight gain in children with acute lymphoblastic leukemia by early nutritional intervention.|2021|Browne EK,Inaba H,|

Spontaneous Partial Remission in a Child With B-Lineage Acute Lymphoblastic Leukemia an...
https://doi.org/10.1097/MPH.0000000000002132
Journal of Pediatric Hematology/oncology; Chtioui H, Ceppi F et. al.

Feb 24th, 2021 - A 2.5-year-old boy presented to his pediatrician with progressive pallor, asthenia, fever, splenomegaly, and hematomas. Leukemia was suspected, and a bone marrow aspirate confirmed acute lymphoblastic leukemia. Before chemotherapy induction, the c...

Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiop...
https://doi.org/10.1097/MPH.0000000000002085
Journal of Pediatric Hematology/oncology; Kudo K, Sato T et. al.

Feb 24th, 2021 - Although thiopurine is a crucial drug for treating acute lymphoblastic leukemia, individual variations in intolerance are observed due to gene polymorphisms. A 3-year-old boy with B-cell precursor acute lymphoblastic leukemia who was administered ...

Comparison of Total Body Irradiation-based Versus Chemotherapy-based Conditionings for ...
https://doi.org/10.1097/MPH.0000000000002055
Journal of Pediatric Hematology/oncology; Yalcin K, Pehlivan B et. al.

Feb 24th, 2021 - Total body irradiation (TBI) is the cornerstone of conditioning regimens in pediatric hematopoietic stem cell transplantation for acute lymphoblastic leukemia. As the late effects and survival comparison between TBI and chemotherapy were well anal...

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Guidelines  47 results

Adult Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version
https://www.cancer.gov/types/leukemia/hp/adult-all-treatment-pdq?cid=eb_govdel
National Cancer Institute

Jan 14th, 2021 - ALL (also called acute lymphocytic leukemia) is an aggressive type of leukemia characterized by the presence of too many lymphoblasts or lymphocytes in the bone marrow and peripheral blood. It can spread to the lymph nodes, spleen, liver, central ...

Children with Down syndrome, ALL at higher risk for poor outcomes
https://www.healio.com/hematology-oncology/leukemia/news/online/{4b3c1cc4-4e4a-462e-b738-7ee6b1d20fd3}/children-with-down-syndrome-all-at-higher-risk-for-poor-outcomes

May 30th, 2020 - Children with Down syndrome and acute lymphoblastic leukemia continue to experience poorer outcomes than children with ALL who do not have Down syndrome, according to study results presented during the ASCO20 Virtual Scientific Program.

Strict Cytogenetics, MRD Criteria Identifies Pediatric B-ALL Subgroup With Favorable Prognosis
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200195/full/

May 28th, 2020 - Application of a set of stringent clinical and cytogenetic features as well as minimal residual disease (MRD) criteria can identify a subset of low-risk (LR) pediatric patients with standard-risk B-cell acute lymphoblastic leukemia (B-ALL) who can...

Tisagenlecleucel Outcomes in Trial of Pediatric, Young Adult R/R ALL Are Consistent With Those Previously Reported
https://dailynews.ascopubs.org/do/10.1200/ADN.20.200130/full/

May 12th, 2020 - In pediatric and young adult patients with relapsed/refractory acute lymphoblastic leukemia (ALL) who received prior blinatumomab exposure or inotuzumab ozogamicin as bridging therapy, treatment with tisagenlecleucel is associated with consistent ...

Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelin...
https://doi.org/10.6004/jnccn.2020.0001
Journal of the National Comprehensive Cancer Network : JN... Brown P, Inaba H et. al.

Jan 7th, 2020 - Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. Advancements in technology that enhance our understanding of the biology of the disease, risk-adapted therapy, and enhanced supportive care have contributed to improved su...

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Drugs  191 results see all →

Clinicaltrials.gov  18,327 results

Chemotherapy Plus Blinatumomab for Philadelphia Chromosome–Negative B-Cell ALL
https://ascopost.com/issues/february-25-2021-supplement-conference-highlights-ash-2020/chemotherapy-plus-blinatumomab-for-philadelphia-chromosome-negative-b-cell-all/

Feb 24th, 2021 - Results from a phase II study presented by Nicholas J. Short, MD, and colleagues at the 2020 American Society of Hematology (ASH) Annual Meeting & Exposition showed that first-line treatment with a regimen of chemotherapy combined with the monoclo...

Preventing weight gain in children with acute lymphoblastic leukemia by early nutrition...
https://doi.org/10.1002/pbc.28965
Pediatric Blood & Cancer; Browne EK, Inaba H

Feb 24th, 2021 - Preventing weight gain in children with acute lymphoblastic leukemia by early nutritional intervention.|2021|Browne EK,Inaba H,|

Spontaneous Partial Remission in a Child With B-Lineage Acute Lymphoblastic Leukemia an...
https://doi.org/10.1097/MPH.0000000000002132
Journal of Pediatric Hematology/oncology; Chtioui H, Ceppi F et. al.

Feb 24th, 2021 - A 2.5-year-old boy presented to his pediatrician with progressive pallor, asthenia, fever, splenomegaly, and hematomas. Leukemia was suspected, and a bone marrow aspirate confirmed acute lymphoblastic leukemia. Before chemotherapy induction, the c...

Association of Multiple Gene Polymorphisms Including Homozygous NUDT15 R139C With Thiop...
https://doi.org/10.1097/MPH.0000000000002085
Journal of Pediatric Hematology/oncology; Kudo K, Sato T et. al.

Feb 24th, 2021 - Although thiopurine is a crucial drug for treating acute lymphoblastic leukemia, individual variations in intolerance are observed due to gene polymorphisms. A 3-year-old boy with B-cell precursor acute lymphoblastic leukemia who was administered ...

Comparison of Total Body Irradiation-based Versus Chemotherapy-based Conditionings for ...
https://doi.org/10.1097/MPH.0000000000002055
Journal of Pediatric Hematology/oncology; Yalcin K, Pehlivan B et. al.

Feb 24th, 2021 - Total body irradiation (TBI) is the cornerstone of conditioning regimens in pediatric hematopoietic stem cell transplantation for acute lymphoblastic leukemia. As the late effects and survival comparison between TBI and chemotherapy were well anal...

see more →

News  1,185 results

TBI Beats Chemoconditioning for ALL Transplants in Children
https://www.medscape.com/viewarticle/945225

Feb 2nd, 2021 - For now at least, total body irradiation (TBI) plus etoposide remains the conditioning regimen of choice for children undergoing allogeneic hematopoietic stem cell transplant for acute lymphoblastic leukemia (ALL), according to an open-label phase...

Adult Acute Lymphoblastic Leukemia Treatment (PDQ®)–Health Professional Version
https://www.cancer.gov/types/leukemia/hp/adult-all-treatment-pdq?cid=eb_govdel
National Cancer Institute

Jan 14th, 2021 - ALL (also called acute lymphocytic leukemia) is an aggressive type of leukemia characterized by the presence of too many lymphoblasts or lymphocytes in the bone marrow and peripheral blood. It can spread to the lymph nodes, spleen, liver, central ...

'Impressive' Outcomes Sans Chemo in Poor-Prognosis ALL
https://www.staging.medscape.com/viewarticle/939520

Oct 20th, 2020 - The days of using chemotherapy to treat Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) may be numbered. In a phase 2 trial, up-front chemo-free induction/consolidation with the tyrosine kinase inhibitor dasatinib (Sprycel)...

New Guideline Helps Patients and Parents Navigate Pediatric Acute Lymphoblastic Leukemia
https://www.staging.medscape.com/viewarticle/938748

Oct 7th, 2020 - NEW YORK (Reuters Health) - A new guideline from the National Comprehensive Cancer Network (NCCN) provides information about pediatric acute lymphoblastic leukemia (ALL) to patients and their families in an easy-to-learn format. The guideline, bas...

New Guideline Helps Patients and Parents Navigate Pediatric Acute Lymphoblastic Leukemia
https://www.medscape.com/viewarticle/938748

Oct 7th, 2020 - NEW YORK (Reuters Health) - A new guideline from the National Comprehensive Cancer Network (NCCN) provides information about pediatric acute lymphoblastic leukemia (ALL) to patients and their families in an easy-to-learn format. The guideline, bas...

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Patient Education  4 results see all →