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About 5,718 results

ALLMedicine™ Acute Promyelocytic Leukemia Center

Research & Reviews  2,757 results

Arsenic trioxide therapy predisposes to herpes zoster reactivation despite minimally my...
https://doi.org/10.1016/j.leukres.2021.106569
Leukemia Research; Glass JL, Derkach A et. al.

Apr 15th, 2021 - Acute Promyelocytic Leukemia (APL) is a unique subtype of acute myeloid leukemia that is highly responsive to minimally myelosuppressive therapy with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO). We and others have observed a higher t...

Long-term survival in an acute promyelocytic leukemia patient with recurrent granulocyt...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036079
Medicine Zhou X, Li C

Apr 9th, 2021 - Granulocytic sarcoma (GS) is an extramedullary myeloid tumor composed of immature cells of the granulocytic series. It rarely occurs in acute promyelocytic leukemia (APL). No case of long-term survival in an APL patient with recurrent GS has been ...

Poly (ADP-ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocy...
https://doi.org/10.1124/jpet.121.000537
The Journal of Pharmacology and Experimental Therapeutics; Giansanti M, De Gabrieli A et. al.

Apr 6th, 2021 - Arsenic trioxide (ATO) is an anticancer agent used for the treatment of acute promyelocytic leukemia (APL). However, 5-10% of patients fail to respond or experience disease relapse. Based on poly(ADP-ribose) polymerase 1 (PARP1) involvement in the...

Acute promyelocytic leukemia with myelofibrosis: A case report and literature review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021289
Medicine Xiao M, Qin L et. al.

Mar 31st, 2021 - Acute promyelocytic leukemia (APL) with myelofibrosis (MF) is rare, and only 14 cases have been reported in the literature to date. A 42-year-old woman was admitted to the hospital with easy bruising and excessive bleeding. With the remission of t...

Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson app...
https://doi.org/10.1002/cncr.33477
Cancer Kantarjian HM, Kadia TM et. al.

Mar 18th, 2021 - The unraveling of the pathophysiology of acute myeloid leukemia (AML) has resulted in rapid translation of the information into clinical practice. After more than 40 years of slow progress in AML research, the US Food and Drug Administration has a...

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Guidelines  2 results

Initial Diagnostic Work-Up of Acute Leukemia: ASCO Clinical Practice Guideline Endorsement o...
http://ascopubs.org/doi/10.1200/JCO.18.01468
de Haas, V.

Dec 2nd, 2018 - The College of American Pathologists (CAP) and the American Society of Hematology (ASH) developed an evidence-based guideline on the initial diagnostic work-up of acute leukemia (AL). Because of the relevance of this topic to the ASCO membership,.

Acute myeloid leukemia, version 2.2013.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161234
Journal of the National Comprehensive Cancer Network : JN... O'Donnell MR, Tallman MS et. al.

Sep 13th, 2013 - These NCCN Guidelines Insights summarize several key updates to the NCCN Guidelines for Acute Myeloid Leukemia and discuss the clinical evidence that support the recommendations. The updates described in this article focus on the acute promyelocyt...

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Drugs  23 results see all →

Clinicaltrials.gov  2,859 results

Arsenic trioxide therapy predisposes to herpes zoster reactivation despite minimally my...
https://doi.org/10.1016/j.leukres.2021.106569
Leukemia Research; Glass JL, Derkach A et. al.

Apr 15th, 2021 - Acute Promyelocytic Leukemia (APL) is a unique subtype of acute myeloid leukemia that is highly responsive to minimally myelosuppressive therapy with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO). We and others have observed a higher t...

Long-term survival in an acute promyelocytic leukemia patient with recurrent granulocyt...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8036079
Medicine Zhou X, Li C

Apr 9th, 2021 - Granulocytic sarcoma (GS) is an extramedullary myeloid tumor composed of immature cells of the granulocytic series. It rarely occurs in acute promyelocytic leukemia (APL). No case of long-term survival in an APL patient with recurrent GS has been ...

Poly (ADP-ribose) polymerase inhibitors for arsenic trioxide-resistant acute promyelocy...
https://doi.org/10.1124/jpet.121.000537
The Journal of Pharmacology and Experimental Therapeutics; Giansanti M, De Gabrieli A et. al.

Apr 6th, 2021 - Arsenic trioxide (ATO) is an anticancer agent used for the treatment of acute promyelocytic leukemia (APL). However, 5-10% of patients fail to respond or experience disease relapse. Based on poly(ADP-ribose) polymerase 1 (PARP1) involvement in the...

Acute promyelocytic leukemia with myelofibrosis: A case report and literature review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8021289
Medicine Xiao M, Qin L et. al.

Mar 31st, 2021 - Acute promyelocytic leukemia (APL) with myelofibrosis (MF) is rare, and only 14 cases have been reported in the literature to date. A 42-year-old woman was admitted to the hospital with easy bruising and excessive bleeding. With the remission of t...

Tretinoin - tretinoin capsule-Bryant Ranch Prepack
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=844941d4-f557-42cf-b7fa-5bd7574925f6

Mar 28th, 2021 - Tretinoin capsules are indicated for the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant), characterized by the presence of the t(15;17) transloc...

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News  77 results

How to Treat Differentiation Syndrome in APL and AML
https://decisionpoint.medscape.com/oncology/viewarticle/936167

Sep 17th, 2020 - This transcript has been edited for clarity. Differentiation syndrome is a frequent complication while patients have active acute promyelocytic leukemia (APL). First of all, we need to mention that the diagnosis of differentiation syndrome is base...

Don't Overlook Treating Older Patients With Acute Promyelocytic Leukemia, Expert Says
https://www.medscape.com/viewarticle/934124

Jul 16th, 2020 - The estimated one third of patients with acute promyelocytic leukemia (APL) who are older than 60 years of age now enjoy a notably better prognosis than in years past, thanks to the introduction of all-trans retinoic acid (ATRA) and arsenic trioxi...

How a 100-Year-Old Formula Could Stop Lifesaving Cancer Therapy
https://www.staging.medscape.com/viewarticle/917519

Aug 29th, 2019 - While leading his team on a hospital round, Joshua F. Zeidner, MD, saw a note recommending that arsenic trioxide (Trisenox, Teva) should be temporarily discontinued in a 44-year-old woman with acute promyelocytic leukemia (APL). The recommendation...

How a 100-Year-Old Formula Could Stop Lifesaving Cancer Therapy
https://www.medscape.com/viewarticle/917519

Aug 29th, 2019 - While leading his team on a hospital round, Joshua F. Zeidner, MD, saw a note recommending that arsenic trioxide (Trisenox, Teva) should be temporarily discontinued in a 44-year-old woman with acute promyelocytic leukemia (APL). The recommendation...

see more →