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About 654 results

ALLMedicine™ Erythroleukemia Center

Research & Reviews  327 results

Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia...
https://doi.org/10.1016/j.prostaglandins.2021.106553
Prostaglandins & Other Lipid Mediators; Salgado MTSF, Lopes AC et. al.

May 11th, 2021 - This study aimed to characterize the relationship between the COX2 and ALOX5 genes, as well as their link with the multidrug resistance (MDR) phenotype in sensitive (K562) and MDR (K562-Lucena and FEPS) erythroleukemia cells. For this, the inhibit...

LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcripti...
https://doi.org/10.1182/bloodadvances.2020003521
Blood Advances; Kohrogi K, Hino S et. al.

Apr 30th, 2021 - Acute myeloid leukemia (AML) is a heterogenous malignancy characterized by distinct lineage subtypes and various genetic/epigenetic alterations. As with other neoplasms, AML cells have well-known aerobic glycolysis, but metabolic variations depend...

Synergistic effects of LY294002 and ABT199 on the cell cycle in K562, HL60 and KG1a cells.
https://doi.org/10.3892/or.2021.8048
Oncology Reports; Geng Y, Wu W et. al.

Apr 13th, 2021 - The aim of the present study was to investigate the synergistic effect of LY294002 (a PI3K inhibitor) and ABT199 (a BCL2 inhibitor) on the cell cycle in acute myeloid leukemia (AML). The optimal concentration and duration of combined LY294002 and ...

Modeling and targeting of erythroleukemia by hematopoietic genome editing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995291
Blood Iacobucci I, Qu C et. al.

Jan 29th, 2021 - Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using multiplexed genome editing of mouse hematopoietic stem and progenitor cells and transplant a...

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Clinicaltrials.gov  327 results

Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia...
https://doi.org/10.1016/j.prostaglandins.2021.106553
Prostaglandins & Other Lipid Mediators; Salgado MTSF, Lopes AC et. al.

May 11th, 2021 - This study aimed to characterize the relationship between the COX2 and ALOX5 genes, as well as their link with the multidrug resistance (MDR) phenotype in sensitive (K562) and MDR (K562-Lucena and FEPS) erythroleukemia cells. For this, the inhibit...

LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcripti...
https://doi.org/10.1182/bloodadvances.2020003521
Blood Advances; Kohrogi K, Hino S et. al.

Apr 30th, 2021 - Acute myeloid leukemia (AML) is a heterogenous malignancy characterized by distinct lineage subtypes and various genetic/epigenetic alterations. As with other neoplasms, AML cells have well-known aerobic glycolysis, but metabolic variations depend...

Synergistic effects of LY294002 and ABT199 on the cell cycle in K562, HL60 and KG1a cells.
https://doi.org/10.3892/or.2021.8048
Oncology Reports; Geng Y, Wu W et. al.

Apr 13th, 2021 - The aim of the present study was to investigate the synergistic effect of LY294002 (a PI3K inhibitor) and ABT199 (a BCL2 inhibitor) on the cell cycle in acute myeloid leukemia (AML). The optimal concentration and duration of combined LY294002 and ...

Modeling and targeting of erythroleukemia by hematopoietic genome editing.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995291
Blood Iacobucci I, Qu C et. al.

Jan 29th, 2021 - Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using multiplexed genome editing of mouse hematopoietic stem and progenitor cells and transplant a...

see more →