ALLMedicine™ Melanoma Center

Mar 2nd, 2021 - Resistance to immune checkpoint inhibitors (ICIs) is a key challenge in cancer therapy. To elucidate underlying mechanisms, we developed Perturb-CITE-sequencing (Perturb-CITE-seq), enabling pooled clustered regularly interspaced short palindromic ...

Mar 2nd, 2021 - KIT mutations are primarily associated with acral and mucosal melanoma, and have been reported to show higher prevalence in chronic sun-damaged (CSD) than non-CSD melanomas. To investigate the prevalence of KIT mutations in melanoma according to s...

Mar 2nd, 2021 - Organ transplant recipients (OTR) are at marked increased risk of skin cancer and skin infections compared to the general population. The purpose of this study was to acquire long-term incidence data on commonly occurring skin diseases in four dif...

Mar 2nd, 2021 - Red kidney bean coat (RKBC) extract contains bioactive compounds that are known to exhibit anti-melanoma activity in vitro. However, knowledge on antitumor component and mechanism of RKBC extract has not been fully clarified. Here, RKBC extract wa...

Mar 2nd, 2021 - Interleukin-1β (IL-1β)-mediated inflammation suppresses antitumor immunity, leading to the generation of a tumor-permissive environment, tumor growth, and progression. Here, we demonstrate that nucleotide-binding domain, leucine-rich containing fa...

Aug 28th, 2020 - Immune checkpoint inhibitors (ICIs) have emerged as the newest pillar of cancer treatment, transforming outcomes in melanoma and showing benefit in a range of malignancies. Immune-mediated toxicities, stemming from increased activity within the T ...

Aug 8th, 2020 - The European Society for Medical Oncology (ESMO) held a consensus conference on melanoma on 5-7 September 2019 in Amsterdam, The Netherlands. The conference included a multidisciplinary panel of 32 leading experts in the management of melanoma. Th...

Aug 8th, 2020 - The European Society for Medical Oncology (ESMO) held a consensus conference on melanoma on 5-7 September 2019 in Amsterdam, The Netherlands. The conference included a multidisciplinary panel of 32 leading experts in the management of melanoma. Th...

Jul 9th, 2020

Jun 24th, 2020 - The ASCO20 Virtual Scientific Program featured a range of studies showcasing the latest advances and clinical breakthroughs in melanoma research.

Mar 2nd, 2021 - Resistance to immune checkpoint inhibitors (ICIs) is a key challenge in cancer therapy. To elucidate underlying mechanisms, we developed Perturb-CITE-sequencing (Perturb-CITE-seq), enabling pooled clustered regularly interspaced short palindromic ...

Mar 2nd, 2021 - KIT mutations are primarily associated with acral and mucosal melanoma, and have been reported to show higher prevalence in chronic sun-damaged (CSD) than non-CSD melanomas. To investigate the prevalence of KIT mutations in melanoma according to s...

Mar 2nd, 2021 - Organ transplant recipients (OTR) are at marked increased risk of skin cancer and skin infections compared to the general population. The purpose of this study was to acquire long-term incidence data on commonly occurring skin diseases in four dif...

Mar 2nd, 2021 - Red kidney bean coat (RKBC) extract contains bioactive compounds that are known to exhibit anti-melanoma activity in vitro. However, knowledge on antitumor component and mechanism of RKBC extract has not been fully clarified. Here, RKBC extract wa...

Mar 2nd, 2021 - Interleukin-1β (IL-1β)-mediated inflammation suppresses antitumor immunity, leading to the generation of a tumor-permissive environment, tumor growth, and progression. Here, we demonstrate that nucleotide-binding domain, leucine-rich containing fa...

Feb 28th, 2021 - A new artificial intelligence (AI) program can effectively identify potential melanoma in wide-field photos, researchers say. The system could use photographs of large areas of patients' bodies taken with ordinary cameras in primary care or by the...

Feb 23rd, 2021 - NEW YORK (Reuters Health) - Circulating tumor DNA (ctDNA) levels can be used to track treatment progress and predict outcomes in patients with BRAF V600 mutation-positive unresectable or metastatic melanoma, analyses of two pivotal studies shows. ...

Feb 16th, 2021 - Patients with advanced melanoma and preexisting autoimmune diseases (AIDs) who were treated with immune checkpoint inhibitors (ICIs) responded well and did not suffer more grade 3 or higher immune-related adverse events than patients without an AI...

Feb 7th, 2021 - NEW YORK (Reuters Health) - A small number of high-risk melanoma patients have continued to show durable CD4+ and CD8+ T cell responses against the majority of immunizing epitopes originally prompted by receipt of NeoVax, a vaccine targeting multi...

Feb 4th, 2021 - Patients with advanced melanoma who had previously not responded to immunotherapy showed a response after treatment with fecal transplants. The material for the fecal transplants was obtained from patients who were experiencing a response to immun...