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About 7,470 results

ALLMedicine™ Astrocytoma Center

Research & Reviews  3,621 results

TERT promoter mutation: is it enough to call a WHO grade II astrocytoma IDH-wildtype gl...
https://doi.org/10.1093/neuonc/noab052
Neuro-oncology Giannini C, Giangaspero F

Mar 4th, 2021 - TERT promoter mutation: is it enough to call a WHO grade II astrocytoma IDH-wildtype glioblastoma?|2021|Giannini C,Giangaspero F,|

The diagnostic function of intravoxel incoherent motion for distinguishing between pilo...
https://doi.org/10.1371/journal.pone.0247899
PloS One; Minh Duc N

Mar 1st, 2021 - Intravoxel incoherent motion (IVIM) imaging concurrently measures diffusion and perfusion parameters and has potential applications for brain tumor classification. However, the effectiveness of IVIM for the differentiation between pilocytic astroc...

Safe Administration of ECT in a Suicidal Patient With a Space-Occupying Astrocytoma.
https://doi.org/10.1097/YCT.0000000000000749
The Journal of ECT; Youssef NA, Casola B et. al.

Feb 24th, 2021 - Electroconvulsive therapy (ECT) can be lifesaving for patients suffering from treatment-resistant psychiatric conditions, especially acute suicidality or depression. However, space-occupying lesions pose risks associated with ECT use due in part t...

Diffuse Gliomas of the Brainstem and Cerebellum in Adults Show Molecular Heterogeneity.
https://doi.org/10.1097/PAS.0000000000001690
The American Journal of Surgical Pathology; Eschbacher KL, Ida CM et. al.

Feb 19th, 2021 - Posterior fossa (PF) diffuse gliomas in pediatric patients frequently harbor the H3 K27M mutation. Among adults, PF diffuse gliomas are rare, with limited data regarding molecular features and clinical outcomes. We identified 28 adult PF diffuse g...

Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism wi...
https://doi.org/10.1038/s41397-021-00206-y 10.1007/s11864-000-0073-2 10.1007/s00401-016-1545-1 10.1016/S1470-2045(09)70025-7 10.1016/j.gendis.2016.04.007 10.2147/CMAR.S5598 10.1038/s41598-018-25169-2 10.1146/annurev.pharmtox.39.1.361 10.1146/annurev.bi.62.070193.002125 10.1038/sj.gt.3300962 10.1093/annonc/mdn548 10.1067/mcp.2001.114164 10.1080/10915810600746023 10.1177/030089161009600110 10.1016/S0169-409X(02)00064-9 10.1016/j.clpt.2003.09.012 10.1126/science.1135308 10.1002/ijc.1306 10.1097/00008571-200208000-00002 10.1023/A:1015735815111 10.1097/FPC.0b013e3283385a1c 10.1097/00008571-200308000-00006 10.2133/dmpk.21.126 10.1097/00008571-200302000-00005 10.1016/S1734-1140(11)70593-X 10.1007/s00228-003-0606-2 10.1111/j.1365-2125.2008.03189.x 10.3109/10428194.2012.736980 10.1111/j.1349-7006.2008.00744.x 10.4238/2015.February.13.3 10.1016/j.canep.2013.04.012 10.1158/1078-0432.CCR-09-1349 10.2165/00003088-200342010-00003 10.1007/s40262-020-00867-1 10.1007/BF00689638 10.3171/2014.10.FOCUS12367 10.1158/0008-5472.CAN-04-0452 10.1007/s11912-017-0585-6 10.1371/journal.pone.0068782 10.1111/cas.12560 10.1016/j.biopha.2018.02.038
The Pharmacogenomics Journal; Munisamy M, Munisamy S et. al.

Feb 16th, 2021 - Temozolomide (TMZ), an alkylating agent with a broad-spectrum antitumor activity, ability to cross blood-brain barrier (BBB), shown to be effective against malignant glioma. This study aims to investigate the effect of 1236C>T (rs1128503) single-n...

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Guidelines  3 results

The role of surgery in the management of patients with diffuse low grade glioma: A syst...
https://doi.org/10.1007/s11060-015-1867-1
Journal of Neuro-oncology; Aghi MK, Nahed BV et. al.

Nov 4th, 2015 - Should patients with imaging suggestive of low grade glioma (LGG) undergo observation versus treatment involving a surgical procedure? These recommendations apply to adults with imaging suggestive of a WHO grade 2 glioma (oligodendroglioma, astroc...

The role of initial chemotherapy for the treatment of adults with diffuse low grade gli...
https://doi.org/10.1007/s11060-015-1931-x
Journal of Neuro-oncology; Ziu M, Kalkanis SN et. al.

Nov 4th, 2015 - Adult patients (older than 18 years of age) with newly diagnosed World Health Organization (WHO) Grade II gliomas (Oligodendroglioma, astrocytoma, mixed oligoastrocytoma). Is there a role for chemotherapy as adjuvant therapy of choice in treatment...

Management of patients with recurrence of diffuse low grade glioma: A systematic review...
https://doi.org/10.1007/s11060-015-1910-2
Journal of Neuro-oncology; Nahed BV, Redjal N et. al.

Nov 4th, 2015 - These recommendations apply to adult patients with recurrent low-grade glioma (LGG) with initial pathologic diagnosis of a WHO grade II infiltrative glioma (oligodendroglioma, astrocytoma, or oligo-astrocytoma). Do pathologic and molecular charac...

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Drugs  45 results see all →

Clinicaltrials.gov  3,747 results

TERT promoter mutation: is it enough to call a WHO grade II astrocytoma IDH-wildtype gl...
https://doi.org/10.1093/neuonc/noab052
Neuro-oncology Giannini C, Giangaspero F

Mar 4th, 2021 - TERT promoter mutation: is it enough to call a WHO grade II astrocytoma IDH-wildtype glioblastoma?|2021|Giannini C,Giangaspero F,|

The diagnostic function of intravoxel incoherent motion for distinguishing between pilo...
https://doi.org/10.1371/journal.pone.0247899
PloS One; Minh Duc N

Mar 1st, 2021 - Intravoxel incoherent motion (IVIM) imaging concurrently measures diffusion and perfusion parameters and has potential applications for brain tumor classification. However, the effectiveness of IVIM for the differentiation between pilocytic astroc...

Safe Administration of ECT in a Suicidal Patient With a Space-Occupying Astrocytoma.
https://doi.org/10.1097/YCT.0000000000000749
The Journal of ECT; Youssef NA, Casola B et. al.

Feb 24th, 2021 - Electroconvulsive therapy (ECT) can be lifesaving for patients suffering from treatment-resistant psychiatric conditions, especially acute suicidality or depression. However, space-occupying lesions pose risks associated with ECT use due in part t...

Diffuse Gliomas of the Brainstem and Cerebellum in Adults Show Molecular Heterogeneity.
https://doi.org/10.1097/PAS.0000000000001690
The American Journal of Surgical Pathology; Eschbacher KL, Ida CM et. al.

Feb 19th, 2021 - Posterior fossa (PF) diffuse gliomas in pediatric patients frequently harbor the H3 K27M mutation. Among adults, PF diffuse gliomas are rare, with limited data regarding molecular features and clinical outcomes. We identified 28 adult PF diffuse g...

Pharmacogenetics of ATP binding cassette transporter MDR1(1236C>T) gene polymorphism wi...
https://doi.org/10.1038/s41397-021-00206-y 10.1007/s11864-000-0073-2 10.1007/s00401-016-1545-1 10.1016/S1470-2045(09)70025-7 10.1016/j.gendis.2016.04.007 10.2147/CMAR.S5598 10.1038/s41598-018-25169-2 10.1146/annurev.pharmtox.39.1.361 10.1146/annurev.bi.62.070193.002125 10.1038/sj.gt.3300962 10.1093/annonc/mdn548 10.1067/mcp.2001.114164 10.1080/10915810600746023 10.1177/030089161009600110 10.1016/S0169-409X(02)00064-9 10.1016/j.clpt.2003.09.012 10.1126/science.1135308 10.1002/ijc.1306 10.1097/00008571-200208000-00002 10.1023/A:1015735815111 10.1097/FPC.0b013e3283385a1c 10.1097/00008571-200308000-00006 10.2133/dmpk.21.126 10.1097/00008571-200302000-00005 10.1016/S1734-1140(11)70593-X 10.1007/s00228-003-0606-2 10.1111/j.1365-2125.2008.03189.x 10.3109/10428194.2012.736980 10.1111/j.1349-7006.2008.00744.x 10.4238/2015.February.13.3 10.1016/j.canep.2013.04.012 10.1158/1078-0432.CCR-09-1349 10.2165/00003088-200342010-00003 10.1007/s40262-020-00867-1 10.1007/BF00689638 10.3171/2014.10.FOCUS12367 10.1158/0008-5472.CAN-04-0452 10.1007/s11912-017-0585-6 10.1371/journal.pone.0068782 10.1111/cas.12560 10.1016/j.biopha.2018.02.038
The Pharmacogenomics Journal; Munisamy M, Munisamy S et. al.

Feb 16th, 2021 - Temozolomide (TMZ), an alkylating agent with a broad-spectrum antitumor activity, ability to cross blood-brain barrier (BBB), shown to be effective against malignant glioma. This study aims to investigate the effect of 1236C>T (rs1128503) single-n...

see more →

News  51 results

Combination Treatment Fails to Improve Survival in Recurrent Glioma
https://www.staging.medscape.com/viewarticle/940391

Nov 4th, 2020 - NEW YORK (Reuters Health) - Following tumor resection in patients with recurrent glioblastoma and anaplastic astrocytoma, treatment with vocimagene amiretrorepvec (Toca 511) and with flucytosine (Toca FC) provides no improvement in overall surviva...

Combination Treatment Fails to Improve Survival in Recurrent Glioma
https://www.medscape.com/viewarticle/940391

Nov 4th, 2020 - NEW YORK (Reuters Health) - Following tumor resection in patients with recurrent glioblastoma and anaplastic astrocytoma, treatment with vocimagene amiretrorepvec (Toca 511) and with flucytosine (Toca FC) provides no improvement in overall surviva...

CHMP recommends approval for generic carmustine
https://www.mdedge.com/hematology-oncology/article/184984/lymphoma-plasma-cell-disorders/chmp-recommends-approval-generic-carmustine
HT Staff

Apr 28th, 2018 - Hodgkin lymphoma Micrograph showing The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion of Carmustine Obvius, a generic version of Carmubris. The CHMP is recommending marketing autho.

Novel Combo Explored for Rare Brain Tumor
https://www.onclive.com/publications/oncology-live/2018/vol-19-no-5/novel-combo-explored-for-rare-brain-tumor

Mar 4th, 2018 - Victor A. Levin, MD Investigators are seeking to determine whether the combination of eflornithine (alphadifluoromethylornithine) with lomustine can improve survival for patients with recurrent anaplastic astrocytoma (AA). A rare form of brain tum...

Severe Headache, Nausea, and Diplopia in a Teenage Girl
https://reference.medscape.com/viewarticle/753945_4

Jan 23rd, 2018 - Intraventricular meningiomas account for 15%-17% of meningiomas in pediatric patients, but only 1.6% of meningiomas in adults.[6] Only 50 reported cases of third ventricle meningioma exist in the literature, and the majority of these lesions are f...

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Patient Education  3 results see all →