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About 6,578 results

ALLMedicine™ Brain Metastasis Center

Research & Reviews  3,189 results

Theranostic AGuIX nanoparticles as radiosensitizer: A phase I, dose-escalation study in...
https://doi.org/10.1016/j.radonc.2021.04.021
Radiotherapy and Oncology : Journal of the European Socie... Verry C, Dufort S et. al.

May 7th, 2021 - Brain metastasis impacts greatly on patients' quality of life and survival. The phase I NANO-RAD trial assessed the safety and maximum tolerated dose of systemic administration of a novel gadolinium-based nanoparticle, AGuIX, in combination with w...

Metabolic target for brain metastasis.
https://doi.org/10.1038/d41573-021-00073-z 10.1038/s43018-021-00183-y
Nature Reviews. Drug Discovery; Kingwell K

May 5th, 2021 - Metabolic target for brain metastasis.|2021|Kingwell K,|

Current status of gastrointestinal tract cancer brain metastasis and the use of blood-b...
https://doi.org/10.1007/s10585-021-10094-y 10.1016/j.bbcan.2016.12.001 10.1136/jcp.2003.013623 10.1007/s11912-011-0203-y 10.1016/s0305-7372(03)00105-1 10.3748/wjg.v10.i22.3345 10.4103/2152-7806.111298 10.1016/s2468-1253(19)30328-0 10.3322/caac.21492 10.1016/j.wneu.2013.02.058 10.1016/j.athoracsur.2019.09.028 10.1002/cncr.10271 10.3389/fonc.2018.00302 10.1111/ijcp.12395 10.1002/cncr.11737 10.1016/j.surneu.2006.05.065 10.1097/md.0000000000016653 10.1002/cncr.25940 10.1007/s10434-999-0771-3 10.1007/s005950070112 10.1007/s11060-010-0405-4 10.1016/j.ijrobp.2009.08.025 10.1016/j.rpor.2014.08.003 10.1111/his.12744 10.3978/j.issn.2304-3865.2015.06.04 10.1634/theoncologist.2018-0152 10.1023/b:neon.0000014517.56866.bc 10.1186/s12885-019-6316-7 10.1200/jco.2002.20.3.870 10.2176/nmc.cr2012-0426 10.3816/CCC.2009.n.016 10.1038/sj.bjc.6605373 10.1159/000478661 10.1002/cncr.29196 10.1111/j.1445-2197.2007.04092.x 10.1007/bf02305763 10.1002/(sici)1097-0142(19960815)78:4<711::Aid-cncr3>3.0.Co;2-h 10.1212/WNL.0b013e31828f183f 10.1007/s10549-015-3610-1 10.1093/neuonc/nox066 10.1046/j.0022-202x.2001.01417.x 10.18632/oncotarget.336 10.2147/ott.S129004 10.1016/j.ejca.2017.03.036 10.1245/s10434-008-0131-8 10.1016/j.canlet.2013.04.021 10.1097/sla.0000000000001130 10.1097/sla.0000000000003406 10.3390/cancers10120527 10.1186/s13046-019-1180-5 10.3389/fgene.2016.00011 10.18632/oncotarget.4096 10.1093/neuonc/nos074 10.3390/cancers12061692 10.7150/jca.34723 10.1007/s12038-018-9805-y 10.1097/SLA.0b013e3182a6909d 10.1002/jcla.23004 10.3892/ol.2011.497 10.1038/ncomms9839 10.1373/clinchem.2014.235457 10.1200/jco.2016.66.6487 10.18632/oncotarget.13397 10.1007/s11060-016-2081-5 10.1016/j.jmoldx.2014.04.008 10.2217/cns-2018-0015 10.3748/wjg.v25.i17.2099 10.1038/s12276-019-0292-5 10.1007/s10120-018-0852-8 10.1371/journal.pone.0214872 10.1007/s10120-016-0599-z 10.1038/s41568-019-0220-y 10.3389/fnins.2019.00297 10.4103/2152-7806.111303 10.3390/ijms131215784
Clinical & Experimental Metastasis; Shoji Y, Furuhashi S et. al.

May 5th, 2021 - Brain metastasis (BM) frequently occurs in patients with cutaneous melanoma, lung, and breast cancer; although, BM rarely arises from cancers of the gastrointestinal tract (GIT). The reported incidence of GIT cancer BM is less than 4%. In the last...

Comparative genomic characterization of melanoma of known and unknown primary.
https://doi.org/10.1007/s12094-021-02629-2
Clinical & Translational Oncology : Official Publication ... Rassy E, Boussios S et. al.

May 2nd, 2021 - This study aims to genomically characterize melanoma of unknown primary (MUP) in comparison to melanomas of cutaneous primary (MCP). Eligible cases were collected from the MSK-IMPACT™ Clinical Sequencing Cohort published in the cBioPortal database...

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Guidelines  9 results

A Cancer Care Ontario Organizational Guideline for the Delivery of Stereotactic Radiosu...
https://doi.org/10.1016/j.prro.2019.11.002
Practical Radiation Oncology; Sahgal A, Kellett S et. al.

Nov 29th, 2019 - In Ontario, Canada, there is increasing demand for stereotactic radiosurgery (SRS) for brain metastases. Recommendations for safe SRS delivery are needed to ensure that patients receive an equitable level of care across the province. This guidelin...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Treatment of Adults With Metastatic Brain Tumors
https://www.cns.org/guidelines/guidelines-treatment-adults-metastatic-brain-tumors/chapter_1
Olson,J.,et al

Jan 8th, 2019 - This series of guidelines was constructed to assess the most current and clinically relevant evidence for management of metastatic brain tumors. They set a benchmark regarding the current evidence base for this management while also highlighting i...

Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases: ASCO Clinical Practice Guideline Update
http://ascopubs.org/doi/full/10.1200/JCO.2018.79.2713
Ramakrishna,N.,et al

Jun 24th, 2018 - Patients with brain metastases should receive appropriate local therapy and systemic therapy, if indicated. Local therapies include surgery, whole-brain radiotherapy, and stereotactic radiosurgery. Treatments depend on factors such as patient prog...

The impact of EGFR mutations on the incidence and survival of stages I to III NSCLC patients with subsequent brain metastasis
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192161

Feb 14th, 2018 - Previous studies have demonstrated the association between EGFR mutations and distant metastasis. However, the association for subsequent brain metastasis (BM) in stages I-III non-small cell lung cancer (NSCLC) patients remains inconclusive. We co...

Radiotherapeutic and surgical management for newly diagnosed brain metastasis/es
https://www.practicalradonc.org/article/S1879-8500(11)00380-8/pdf

Apr 16th, 2017 - To systematically review the evidence for the radiotherapeutic and surgical management of patients newly diagnosed with intraparenchymal brain metastases.

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Clinicaltrials.gov  3,293 results

Theranostic AGuIX nanoparticles as radiosensitizer: A phase I, dose-escalation study in...
https://doi.org/10.1016/j.radonc.2021.04.021
Radiotherapy and Oncology : Journal of the European Socie... Verry C, Dufort S et. al.

May 7th, 2021 - Brain metastasis impacts greatly on patients' quality of life and survival. The phase I NANO-RAD trial assessed the safety and maximum tolerated dose of systemic administration of a novel gadolinium-based nanoparticle, AGuIX, in combination with w...

Metabolic target for brain metastasis.
https://doi.org/10.1038/d41573-021-00073-z 10.1038/s43018-021-00183-y
Nature Reviews. Drug Discovery; Kingwell K

May 5th, 2021 - Metabolic target for brain metastasis.|2021|Kingwell K,|

Current status of gastrointestinal tract cancer brain metastasis and the use of blood-b...
https://doi.org/10.1007/s10585-021-10094-y 10.1016/j.bbcan.2016.12.001 10.1136/jcp.2003.013623 10.1007/s11912-011-0203-y 10.1016/s0305-7372(03)00105-1 10.3748/wjg.v10.i22.3345 10.4103/2152-7806.111298 10.1016/s2468-1253(19)30328-0 10.3322/caac.21492 10.1016/j.wneu.2013.02.058 10.1016/j.athoracsur.2019.09.028 10.1002/cncr.10271 10.3389/fonc.2018.00302 10.1111/ijcp.12395 10.1002/cncr.11737 10.1016/j.surneu.2006.05.065 10.1097/md.0000000000016653 10.1002/cncr.25940 10.1007/s10434-999-0771-3 10.1007/s005950070112 10.1007/s11060-010-0405-4 10.1016/j.ijrobp.2009.08.025 10.1016/j.rpor.2014.08.003 10.1111/his.12744 10.3978/j.issn.2304-3865.2015.06.04 10.1634/theoncologist.2018-0152 10.1023/b:neon.0000014517.56866.bc 10.1186/s12885-019-6316-7 10.1200/jco.2002.20.3.870 10.2176/nmc.cr2012-0426 10.3816/CCC.2009.n.016 10.1038/sj.bjc.6605373 10.1159/000478661 10.1002/cncr.29196 10.1111/j.1445-2197.2007.04092.x 10.1007/bf02305763 10.1002/(sici)1097-0142(19960815)78:4<711::Aid-cncr3>3.0.Co;2-h 10.1212/WNL.0b013e31828f183f 10.1007/s10549-015-3610-1 10.1093/neuonc/nox066 10.1046/j.0022-202x.2001.01417.x 10.18632/oncotarget.336 10.2147/ott.S129004 10.1016/j.ejca.2017.03.036 10.1245/s10434-008-0131-8 10.1016/j.canlet.2013.04.021 10.1097/sla.0000000000001130 10.1097/sla.0000000000003406 10.3390/cancers10120527 10.1186/s13046-019-1180-5 10.3389/fgene.2016.00011 10.18632/oncotarget.4096 10.1093/neuonc/nos074 10.3390/cancers12061692 10.7150/jca.34723 10.1007/s12038-018-9805-y 10.1097/SLA.0b013e3182a6909d 10.1002/jcla.23004 10.3892/ol.2011.497 10.1038/ncomms9839 10.1373/clinchem.2014.235457 10.1200/jco.2016.66.6487 10.18632/oncotarget.13397 10.1007/s11060-016-2081-5 10.1016/j.jmoldx.2014.04.008 10.2217/cns-2018-0015 10.3748/wjg.v25.i17.2099 10.1038/s12276-019-0292-5 10.1007/s10120-018-0852-8 10.1371/journal.pone.0214872 10.1007/s10120-016-0599-z 10.1038/s41568-019-0220-y 10.3389/fnins.2019.00297 10.4103/2152-7806.111303 10.3390/ijms131215784
Clinical & Experimental Metastasis; Shoji Y, Furuhashi S et. al.

May 5th, 2021 - Brain metastasis (BM) frequently occurs in patients with cutaneous melanoma, lung, and breast cancer; although, BM rarely arises from cancers of the gastrointestinal tract (GIT). The reported incidence of GIT cancer BM is less than 4%. In the last...

Comparative genomic characterization of melanoma of known and unknown primary.
https://doi.org/10.1007/s12094-021-02629-2
Clinical & Translational Oncology : Official Publication ... Rassy E, Boussios S et. al.

May 2nd, 2021 - This study aims to genomically characterize melanoma of unknown primary (MUP) in comparison to melanomas of cutaneous primary (MCP). Eligible cases were collected from the MSK-IMPACT™ Clinical Sequencing Cohort published in the cBioPortal database...

see more →

News  87 results

SRS Instead of WBRT for Patients With Multiple Brain Metastases
https://www.medscape.com/viewarticle/939923

Oct 27th, 2020 - Stereotactic radiosurgery (SRS) should replace whole-brain radiotherapy (WBRT) as the new standard of care for patients with four or more brain metastases, say researchers who report results from a randomized trial conducted in patients with four ...

A 64-Year-Old Man Unable to Lift His Arm or Walk
https://reference.medscape.com/viewarticle/913038_3

May 20th, 2019 - Discussion The CT findings of a mass with associated edema, along with his history of lung cancer, strongly suggested brain metastasis (Figure 1). (Enlarge Image) Figure 1. In this case, a solitary metastasis must be differentiated from a primary ...

Younger patients with NSCLC tend to live longer
https://www.mdedge.com/hematology-oncology/article/200962/lung-cancer/younger-patients-nsclc-tend-live-longer?channel=39313
Caleb Rans

May 15th, 2019 - Younger patients with non–small cell lung cancer (NSCLC) may have better survival, despite higher rates of brain metastasis and driver mutations, according to results from a retrospective analysis. “We carried out a comprehensive analysis of patie.

Fast Five Quiz: Metastatic Breast Cancer Signs and Symptoms
https://reference.medscape.com/viewarticle/910327_6

Mar 17th, 2019 - A comprehensive literature review of brain metastasis in brain cancer found that the most common symptoms included headache (35%), vomiting (26%), nausea (23%), hemiparesis (22%), visual changes (13%), and seizures (12%). Other symptoms associated...

Controlling Brain Mets: Using Radiotherapy for Quality of Life
https://www.staging.medscape.com/viewarticle/909162

Mar 13th, 2019 - This transcript has been edited for clarity. Hello. This is Mark Kris from Memorial Sloan Kettering (MSK), talking today about a common and difficult problem both for patients and practitioners, and that is the treatment of brain metastases. I'm g...

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