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About 14,780 results

ALLMedicine™ Glioblastoma Multiforme Center

Research & Reviews  7,207 results

Identification of COL6A1 as the Key Gene Associated with Antivascular Endothelial Growt...
https://doi.org/10.1089/gtmb.2020.0279
Genetic Testing and Molecular Biomarkers; Lin H, Yang Y et. al.

May 10th, 2021 - Background: Vascular endothelial growth factors (VEGFs) are important for glioblastoma multiforme (GBM) growth and development. However, the effects of VEGF-targeting drugs in primary GBM remain poorly understood. Aim: We aimed to explore the key ...

Novel CTRP8-RXFP1-JAK3-STAT3 axis promotes Cdc42-dependent actin remodeling for enhance...
https://doi.org/10.1002/1878-0261.12981
Molecular Oncology; Glogowska A, Thanasupawat T et. al.

May 7th, 2021 - CTRP8 is the least studied member of the C1Q-TNF related peptide family. We identified CTRP8 as a ligand of the G protein coupled receptor RXFP1 in glioblastoma multiforme (GBM). The CTRP8-RXFP1 ligand-receptor system protects human GBM cells agai...

Establishment of a Novel Temozolomide Resistant Subline of Glioblastoma Multiforme Cell...
https://doi.org/10.21873/anticanres.15008
Anticancer Research; Ha HA, Yang JS et. al.

May 6th, 2021 - Glioblastoma multiforme (GBM) is a lethal disease with a high rate of chemoresistance to temozolomide (TMZ). The aim of the study was to establish a TMZ-resistant subline from the GBM-8401 cell line to determine the mechanisms of resistance and id...

Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for gliobla...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097796
Journal of Nanobiotechnology; Jena LN, Bennie LA et. al.

May 5th, 2021 - Glioblastoma multiforme (GBM) is an incurable aggressive brain cancer in which current treatment strategies have demonstrated limited survival benefit. In recent years, nitrogen-containing bisphosphonates (N-BPs) have demonstrated direct anticance...

Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregula...
https://doi.org/10.1002/1878-0261.12966
Molecular Oncology; Lee SJ, Choi YJ et. al.

May 1st, 2021 - Targeting autophagy is a promising therapeutic approach in cancer therapy. Here, we screened 30 traditional herbal medicines to identify novel autophagy regulators and found that Platycodon grandiflorus (PG) and platycodin D (PD), a triterpenoid s...

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Guidelines  2 results

The role of radiotherapy in the management of progressive glioblastoma : a systematic r...
https://doi.org/10.1007/s11060-013-1337-6
Journal of Neuro-oncology; Ryu S, Buatti JM et. al.

Apr 14th, 2014 - Can re-irradiation (by using conventional radiotherapy, fractionated radiosurgery, or single fraction radiosurgery) be used in patients with progressive glioblastoma multiforme after the first adjuvant combined multimodality treatment with radiati...

Cytotoxic chemotherapeutic management of newly diagnosed glioblastoma multiforme.
https://doi.org/10.1007/s11060-008-9615-4
Journal of Neuro-oncology; Fadul CE, Wen PY et. al.

Aug 20th, 2008 - Cytotoxic chemotherapeutic management of newly diagnosed glioblastoma multiforme.|2008|Fadul CE,Wen PY,Kim L,Olson JJ,|therapeutic use,drug therapy,therapeutic use,drug therapy,

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Drugs  13 results see all →

Clinicaltrials.gov  7,429 results

Identification of COL6A1 as the Key Gene Associated with Antivascular Endothelial Growt...
https://doi.org/10.1089/gtmb.2020.0279
Genetic Testing and Molecular Biomarkers; Lin H, Yang Y et. al.

May 10th, 2021 - Background: Vascular endothelial growth factors (VEGFs) are important for glioblastoma multiforme (GBM) growth and development. However, the effects of VEGF-targeting drugs in primary GBM remain poorly understood. Aim: We aimed to explore the key ...

Novel CTRP8-RXFP1-JAK3-STAT3 axis promotes Cdc42-dependent actin remodeling for enhance...
https://doi.org/10.1002/1878-0261.12981
Molecular Oncology; Glogowska A, Thanasupawat T et. al.

May 7th, 2021 - CTRP8 is the least studied member of the C1Q-TNF related peptide family. We identified CTRP8 as a ligand of the G protein coupled receptor RXFP1 in glioblastoma multiforme (GBM). The CTRP8-RXFP1 ligand-receptor system protects human GBM cells agai...

Establishment of a Novel Temozolomide Resistant Subline of Glioblastoma Multiforme Cell...
https://doi.org/10.21873/anticanres.15008
Anticancer Research; Ha HA, Yang JS et. al.

May 6th, 2021 - Glioblastoma multiforme (GBM) is a lethal disease with a high rate of chemoresistance to temozolomide (TMZ). The aim of the study was to establish a TMZ-resistant subline from the GBM-8401 cell line to determine the mechanisms of resistance and id...

Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for gliobla...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8097796
Journal of Nanobiotechnology; Jena LN, Bennie LA et. al.

May 5th, 2021 - Glioblastoma multiforme (GBM) is an incurable aggressive brain cancer in which current treatment strategies have demonstrated limited survival benefit. In recent years, nitrogen-containing bisphosphonates (N-BPs) have demonstrated direct anticance...

Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregula...
https://doi.org/10.1002/1878-0261.12966
Molecular Oncology; Lee SJ, Choi YJ et. al.

May 1st, 2021 - Targeting autophagy is a promising therapeutic approach in cancer therapy. Here, we screened 30 traditional herbal medicines to identify novel autophagy regulators and found that Platycodon grandiflorus (PG) and platycodin D (PD), a triterpenoid s...

see more →

News  125 results

An 8-Year-Old Boy With Autism, Lupus, Fever, and Chest Pain
https://reference.staging.medscape.com/viewarticle/932635_5

Jun 22nd, 2020 - Due to limited information about CMMRD, CMMRD-related tumors continue to be treated primarily based on the location and type of cancer. However, these tumors may not respond to traditional treatment strategies. A functional DNA MMR system is often...

Our Failures Demand a New Approach to Cancer
https://www.medscape.com/viewarticle/922169

Dec 4th, 2019 - A few weeks before his death, 23-year-old Andrew—my daughter's best friend—was approached about a DNR (do not resuscitate) order. He was suffering from end-stage brain cancer, but he refused outright to even consider signing. Source: Chad Hunt Tha...

Our Failures Demand a New Approach to Cancer
https://www.staging.medscape.com/viewarticle/922169

Dec 4th, 2019 - A few weeks before his death, 23-year-old Andrew—my daughter's best friend—was approached about a DNR (do not resuscitate) order. He was suffering from end-stage brain cancer, but he refused outright to even consider signing. Source: Chad Hunt Tha...

Fit for Survival; Ringing the Bell; No End to Need for Chemo
https://www.medpagetoday.com/hematologyoncology/othercancers/79728

May 9th, 2019 - Patients with good cardiorespiratory fitness at diagnosis of lung or colorectal cancer were significantly less likely to die of the disease. (Cancer) Bristol-Myers Squibb announced that a phase III clinical trial failed to show a survival benefit ...

Multiple solid tumors targeted by concept CAR T
https://www.mdedge.com/hematology-oncology/article/165978/sarcoma-gist/multiple-solid-tumors-targeted-concept-car-t/page/0/1

May 17th, 2018 - In contrast, B7-H3 is highly expressed on many different pediatric solid tumors, including rhabdomyosarcoma (95% of tumors stained), Ewing sarcoma (89%), Wilms tumor (100%), neuroblastoma (82%), ganglioneuroblastoma and ganglioneuroma (53%), medul.

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Patient Education  4 results see all →