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About 8,302 results

ALLMedicine™ Medulloblastoma Center

Research & Reviews  4,085 results

Downregulation of ARID1B, a tumor-suppressor in the WNT subgroup medulloblastoma, activ...
https://doi.org/10.1093/hmg/ddab134
Human Molecular Genetics; Deogharkar A, Singh SV et. al.

May 5th, 2021 - Medulloblastoma, a common pediatric malignant brain tumor, consists of four distinct molecular subgroups WNT, SHH, Group 3, and Group 4. Exome sequencing of 11 WNT subgroup medulloblastomas from an Indian cohort identified mutations in several chr...

The role of sex genotype in paediatric CNS tumour incidence and survival.
https://doi.org/10.1007/s00381-021-05165-0 10.1016/j.ctrv.2010.02.003 10.1002/bem.20149 10.3322/caac.21332 10.1002/pon.1502 10.1200/JCO.1992.10.5.810 10.1007/s00381-018-3982-8 10.4103/1793-5482.151516 10.1001/jama.279.18.1474 10.1016/0360-3016(94)00476-2 10.1093/neuonc/nos155 10.1002/pbc.27620 10.1158/1055-9965.EPI-14-0207 10.1186/s13293-020-00291-x 10.18295/squmj.2017.17.04.003 10.1101/gr.185926.114 10.1038/ng.3726 10.3389/fimmu.2018.01269 10.1038/nrg2415 10.3389/fimmu.2018.00073 10.1158/1055-9965.EPI-10-0658 10.1007/s11060-020-03467-y 10.1186/s12885-019-5344-7 10.1523/JNEUROSCI.3331-09.2009 10.1152/physiolgenomics.00234.2007 10.1530/REP-10-0482 10.1007/s00401-016-1545-1 10.1038/ng.2936 10.1007/s00381-015-2945-6 10.4103/0971-5851.103142 10.1227/NEU.0000000000000845 10.1016/j.wneu.2017.04.035 10.1042/BSR20180752 10.1016/j.jocn.2012.04.009 10.1007/s00401-011-0922-z 10.1002/pbc.21832 10.1111/his.12770 10.1371/journal.pone.0101623 10.1177/0883073809339212 10.3171/2008.9.JNS08117 10.1002/pbc.21806 10.1016/j.jss.2009.04.024 10.1007/s00018-015-1930-2 10.1097/MPH.0b013e3181983af5 10.1002/cncr.25454 10.1038/s41416-018-0277-5 10.1093/neuonc/nou311 10.1097/PAS.0000000000000749
Child's Nervous System : ChNS : Official Journal of the I... Soon WC, Goacher E et. al.

May 5th, 2021 - Evidence exists, in CNS germinomas and medulloblastomas (MB), that patient sex significantly influences incidence and outcome. The role of sex genotype in other paediatric CNS tumours remains unclear. This study sought to examine the role of sex g...

Adjuvant therapy for high risk medulloblastoma: More is better?
https://doi.org/10.1093/neuonc/noab104
Neuro-oncology Strother D, Lafay-Cousin L

Apr 27th, 2021 - Adjuvant therapy for high risk medulloblastoma: More is better?|2021|Strother D,Lafay-Cousin L,|

Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblast...
https://doi.org/10.21873/cgp.20264
Cancer Genomics & Proteomics; Gershanov S, Toledano H et. al.

Apr 24th, 2021 - Germline mutations in PTCH1 or SUFU in the sonic hedgehog (SHH) pathway cause Gorlin's syndrome with increased risk of developing SHH-subgroup medulloblastoma. Gorlin's syndrome precludes the use of radiotherapy (a standard component of treatment)...

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Guidelines  1 results

SIOP PODC adapted treatment recommendations for standard-risk medulloblastoma in low an...
https://doi.org/10.1002/pbc.25313
Pediatric Blood & Cancer; Parkes J, Hendricks M et. al.

Nov 24th, 2014 - Effective treatment of children with medulloblastoma requires a functioning multi-disciplinary team with adequate neurosurgical, neuroradiological, pathological, radiotherapy and chemotherapy facilities and personnel. In addition the treating cent...

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Drugs  11 results see all →

Clinicaltrials.gov  4,173 results

Downregulation of ARID1B, a tumor-suppressor in the WNT subgroup medulloblastoma, activ...
https://doi.org/10.1093/hmg/ddab134
Human Molecular Genetics; Deogharkar A, Singh SV et. al.

May 5th, 2021 - Medulloblastoma, a common pediatric malignant brain tumor, consists of four distinct molecular subgroups WNT, SHH, Group 3, and Group 4. Exome sequencing of 11 WNT subgroup medulloblastomas from an Indian cohort identified mutations in several chr...

The role of sex genotype in paediatric CNS tumour incidence and survival.
https://doi.org/10.1007/s00381-021-05165-0 10.1016/j.ctrv.2010.02.003 10.1002/bem.20149 10.3322/caac.21332 10.1002/pon.1502 10.1200/JCO.1992.10.5.810 10.1007/s00381-018-3982-8 10.4103/1793-5482.151516 10.1001/jama.279.18.1474 10.1016/0360-3016(94)00476-2 10.1093/neuonc/nos155 10.1002/pbc.27620 10.1158/1055-9965.EPI-14-0207 10.1186/s13293-020-00291-x 10.18295/squmj.2017.17.04.003 10.1101/gr.185926.114 10.1038/ng.3726 10.3389/fimmu.2018.01269 10.1038/nrg2415 10.3389/fimmu.2018.00073 10.1158/1055-9965.EPI-10-0658 10.1007/s11060-020-03467-y 10.1186/s12885-019-5344-7 10.1523/JNEUROSCI.3331-09.2009 10.1152/physiolgenomics.00234.2007 10.1530/REP-10-0482 10.1007/s00401-016-1545-1 10.1038/ng.2936 10.1007/s00381-015-2945-6 10.4103/0971-5851.103142 10.1227/NEU.0000000000000845 10.1016/j.wneu.2017.04.035 10.1042/BSR20180752 10.1016/j.jocn.2012.04.009 10.1007/s00401-011-0922-z 10.1002/pbc.21832 10.1111/his.12770 10.1371/journal.pone.0101623 10.1177/0883073809339212 10.3171/2008.9.JNS08117 10.1002/pbc.21806 10.1016/j.jss.2009.04.024 10.1007/s00018-015-1930-2 10.1097/MPH.0b013e3181983af5 10.1002/cncr.25454 10.1038/s41416-018-0277-5 10.1093/neuonc/nou311 10.1097/PAS.0000000000000749
Child's Nervous System : ChNS : Official Journal of the I... Soon WC, Goacher E et. al.

May 5th, 2021 - Evidence exists, in CNS germinomas and medulloblastomas (MB), that patient sex significantly influences incidence and outcome. The role of sex genotype in other paediatric CNS tumours remains unclear. This study sought to examine the role of sex g...

Adjuvant therapy for high risk medulloblastoma: More is better?
https://doi.org/10.1093/neuonc/noab104
Neuro-oncology Strother D, Lafay-Cousin L

Apr 27th, 2021 - Adjuvant therapy for high risk medulloblastoma: More is better?|2021|Strother D,Lafay-Cousin L,|

Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblast...
https://doi.org/10.21873/cgp.20264
Cancer Genomics & Proteomics; Gershanov S, Toledano H et. al.

Apr 24th, 2021 - Germline mutations in PTCH1 or SUFU in the sonic hedgehog (SHH) pathway cause Gorlin's syndrome with increased risk of developing SHH-subgroup medulloblastoma. Gorlin's syndrome precludes the use of radiotherapy (a standard component of treatment)...

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News  29 results

Better Intellectual Outcomes After Proton Beam for Brain Cancer
https://www.staging.medscape.com/viewarticle/923576

Jan 8th, 2020 - A new study shows that children with medulloblastoma who were treated with radiotherapy had better intellectual outcomes when the radiation was delivered as proton beam therapy compared to traditional photon radiotherapy. Proton beam radiotherapy ...

Better Intellectual Outcomes After Proton Beam for Brain Cancer
https://www.medscape.com/viewarticle/923576

Jan 8th, 2020 - A new study shows that children with medulloblastoma who were treated with radiotherapy had better intellectual outcomes when the radiation was delivered as proton beam therapy compared to traditional photon radiotherapy. Proton beam radiotherapy ...

Identifying Low-Risk Medulloblastoma to De-escalate Therapy
https://www.medscape.com/viewarticle/904596

Nov 7th, 2018 - Some children with the most common form of malignant brain cancer could receive lower-dose radiotherapy and chemotherapy, depending on the chromosome signature of their tumor. Such an approach would improve patients' quality of life and could pote...

Multiple solid tumors targeted by concept CAR T
https://www.mdedge.com/hematology-oncology/article/165978/sarcoma-gist/multiple-solid-tumors-targeted-concept-car-t/page/0/1

May 17th, 2018 - In contrast, B7-H3 is highly expressed on many different pediatric solid tumors, including rhabdomyosarcoma (95% of tumors stained), Ewing sarcoma (89%), Wilms tumor (100%), neuroblastoma (82%), ganglioneuroblastoma and ganglioneuroma (53%), medul.

CHMP recommends approval for generic carmustine
https://www.mdedge.com/hematology-oncology/article/184984/lymphoma-plasma-cell-disorders/chmp-recommends-approval-generic-carmustine
HT Staff

Apr 28th, 2018 - Hodgkin lymphoma Micrograph showing The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion of Carmustine Obvius, a generic version of Carmubris. The CHMP is recommending marketing autho.

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Patient Education  3 results see all →