ALLMedicine™ Medulloblastoma Center
Research & Reviews 1,804 results
https://doi.org/10.3171/2022.7.PEDS2246
Journal of Neurosurgery. Pediatrics; Yang PH, Almgren-Bell A et. al.
Aug 14th, 2022 - Transependymal flow (TEF) of CSF, often delineated as T2-weighted hyperintensity adjacent to the lateral ventricles on MRI, is a known imaging finding, usually in the setting of CSF flow disturbances. Specific radiological features of TEF and thei...
https://clinicaltrials.gov/ct2/show/NCT05096481
Aug 12th, 2022 - This phase II clinical trial will have 3 strata in order to assess the efficacy of a highly immunogenic CMV-directed peptide vaccines in children with (1) recurrent medulloblastoma (rMB), (2) newly-diagnosed high-grade gliomas (HGG) and (3) newly-...
https://emedicine.medscape.com/article/336605-overview
Aug 11th, 2022 - Practice Essentials Arachnoiditis is a broad term denoting inflammation of the meninges and subarachnoid space. It is characterized by thickening of the arachnoid membrane and dura mater adhesions that result in chronic lower back pain. Complicati...
http://emedicine.medscape.com/article/336605-overview
Aug 11th, 2022 - Practice Essentials Arachnoiditis is a broad term denoting inflammation of the meninges and subarachnoid space. It is characterized by thickening of the arachnoid membrane and dura mater adhesions that result in chronic lower back pain. Complicati...
https://clinicaltrials.gov/ct2/show/NCT04485416
Aug 11th, 2022 - Eltrombopag is an orally administered, small molecule thrombopoietin receptor (TPO-R) agonist that stimulates platelet production by a mechanism similar, but not identical to endogenous TPO. Eltrombopag interacts with the transmembrane domain of t...
Guidelines 2 results
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057961
Clinical & Translational Oncology : Official Publication ... Luque R, Benavides M et. al.
Apr 2nd, 2021 - Recent advances in molecular profiling, have reclassified medulloblastoma, an undifferentiated tumor of the posterior fossa, in at least four diseases, each one with differences in prognosis, epidemiology and sensibility to different treatments. T...
https://doi.org/10.1002/pbc.25313
Pediatric Blood & Cancer; Parkes J, Hendricks M et. al.
Nov 25th, 2014 - Effective treatment of children with medulloblastoma requires a functioning multi-disciplinary team with adequate neurosurgical, neuroradiological, pathological, radiotherapy and chemotherapy facilities and personnel. In addition the treating cent...
Drugs 12 results see all →
Clinicaltrials.gov 130 results
https://clinicaltrials.gov/ct2/show/NCT05096481
Aug 12th, 2022 - This phase II clinical trial will have 3 strata in order to assess the efficacy of a highly immunogenic CMV-directed peptide vaccines in children with (1) recurrent medulloblastoma (rMB), (2) newly-diagnosed high-grade gliomas (HGG) and (3) newly-...
https://clinicaltrials.gov/ct2/show/NCT04485416
Aug 11th, 2022 - Eltrombopag is an orally administered, small molecule thrombopoietin receptor (TPO-R) agonist that stimulates platelet production by a mechanism similar, but not identical to endogenous TPO. Eltrombopag interacts with the transmembrane domain of t...
https://clinicaltrials.gov/ct2/show/NCT02359565
Aug 9th, 2022 - PRIMARY OBJECTIVES: I. To establish the safety and describe adverse effects associated with administration of the adult recommended dose of pembrolizumab (MK-3475) in each stratum separately. II. To estimate the sustained objective response rate, ...
https://clinicaltrials.gov/ct2/show/NCT04696029
Aug 4th, 2022 - In this study subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 2500 mg/m2 BID on each day of study. Subjects will be evaluated in 3 Cohorts: Cohort 1: Molecular High Risk Medulloblastoma Cohort 2: Molecular Very H...
https://clinicaltrials.gov/ct2/show/NCT02724579
Aug 1st, 2022 - PRIMARY OBJECTIVE: I. To estimate the progression-free survival (PFS) of children >= 3 years of age with wingless-type MMTV integration site family (WNT)-driven average-risk medulloblastoma using reduced craniospinal radiotherapy (CSI) (18 Gray [G...
News 49 results
https://www.onclive.com/view/fda-accepts-nda-resubmission-for-pedmark-in-prevention-of-platinum-induced-ototoxicity-in-solid-tumors
Apr 28th, 2022 - The FDA has accepted for filing the new drug application (NDA) resubmission for a unique formulation of sodium thiosulfate (Pedmark) for the prevention of platinum-induced ototoxicity in patients between the ages of 1 month and 18 years who have l...
https://www.onclive.com/view/nda-resubmitted-to-fda-for-pedmark-in-prevention-of-cisplatin-induced-ototoxicity-in-solid-tumors
Apr 28th, 2022 - The new drug application seeking the approval of a unique formulation of sodium thiosulfate (Pedmark) for the prevention of ototoxicity induced by cisplatin chemotherapy in patients aged 1 month to less than 18 years of age with localized, nonmeta...
https://www.mdedge.com/dermatology/article/249160/nonmelanoma-skin-cancer/multiple-lesions-recurrent-bleeding
Diem-Phuong D. Dao, BS, Kimberly Salkey, MD
Nov 29th, 2021 - The Diagnosis: Nevoid Basal Cell Carcinoma Syndrome Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is a rare autosomal-dominant disorder that increases the risk for developing various carcinomas and affects multiple o.
https://www.onclive.com/view/new-astro-president-calls-attention-to-in-person-meetings-remaining-challenges-and-ongoing-research-in-radiation-oncology
Nov 24th, 2021 - Following the period of virtual medical meetings due to the COVID-19 pandemic, the field of radiation oncology is navigating the world of hybrid conferences to continue pushing the paradigm forward, said Jeff M. Michalski, MD, MBA, FASTRO, who add...
https://www.onclive.com/view/dr-cohen-addresses-the-role-of-the-hedgehog-pathway
Oct 6th, 2021 - Deirdre J. Cohen, MD, Assistant Professor, Department of Medicine, Clinical Cancer Center, NYU Medical Oncology Associates, at the Cancer Institute at NYU Langone Medical Center, discusses the normal role of the hedgehog signaling pathway and pote...
