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About 640 results

ALLMedicine™ Neuroectodermal Tumors Center

Research & Reviews  220 results

"E-MGNET": Extra-Enteric Malignant Gastrointestinal Neuroectodermal Tumor- A Clinicopat...
https://doi.org/10.1016/j.modpat.2023.100160
Modern Pathology : an Official Journal of the United Stat... Ulici V, Hornick JL et. al.

Mar 20th, 2023 - Malignant gastrointestinal neuroectodermal tumors (MGNET), also known as "gastrointestinal clear cell sarcoma-like tumor", are very rare, aggressive sarcomas characterized by enteric location, distinctive pathologic features, and EWSR1/FUS::ATF1/C...

Experience of CT diagnosis and management of primary renal Ewing's sarcoma: A retrospec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750559
Medicine Hu X, Li D et. al.

Jan 11th, 2023 - To present the clinical experience of primary renal Ewing's sarcoma/primitive neuroectodermal tumors (rEWs/PNET) admitted to our hospital and systematically review the published literature. A retrospective analysis was performed on patients with p...

Screening Key Pathogenic Genes and Small Molecule Compounds for PNET.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949520
Journal of Pediatric Hematology/oncology; Zhou Q, Liu H et. al.

Dec 17th, 2022 - Primitive neuroectodermal tumors (PNET) are rare malignant tumors, but the mortality rate of the patients is extremely high. The aim of this study was to identify the hub genes and pathways involved in the pathogenesis of PNET and to screen the po...

The prognostic factors of Ewing sarcoma/peripheral primitive neuroectodermal tumor: A r...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302321
Medicine Peng J, Han XM

Jul 23rd, 2022 - To investigate the characteristics and factors that impact the prognosis of Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) patients. We retrospectively analyzed ES/pPNET patients diagnosed at our hospital from January 2011 to ...

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
https://clinicaltrials.gov/ct2/show/NCT00336024

Jul 12th, 2022 - PRIMARY OBJECTIVES: I. To determine if treatment of infants with high risk primitive neuroectodermal tumors (PNET) central nervous system (CNS) tumors with intensive chemotherapy plus high-dose methotrexate and peripheral blood stem cell rescue re...

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Clinicaltrials.gov  25 results

Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
https://clinicaltrials.gov/ct2/show/NCT00336024

Jul 12th, 2022 - PRIMARY OBJECTIVES: I. To determine if treatment of infants with high risk primitive neuroectodermal tumors (PNET) central nervous system (CNS) tumors with intensive chemotherapy plus high-dose methotrexate and peripheral blood stem cell rescue re...

Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor
https://clinicaltrials.gov/ct2/show/NCT01326104

Feb 7th, 2022 - Malignant brain tumors now represent the most frequent cause of cancer death in children. Despite aggressive and highly toxic multi-modality therapy including surgery, craniospinal radiation, and high-dose chemotherapy coupled with peripheral bloo...

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors
https://clinicaltrials.gov/ct2/show/NCT01217437

Jul 23rd, 2021 - PRIMARY OBJECTIVES: l. To compare the overall survival (OS) of subjects receiving the combination of temozolomide and irinotecan with that of subjects receiving temozolomide, irinotecan (irinotecan hydrochloride), and bevacizumab for recurrent med...

Ewing Sarcoma Family of Tumors (ESFT): A 15-year Experience From a Tertiary Care Cancer Center in Upper Egypt
https://clinicaltrials.gov/ct2/show/NCT04300179

Dec 17th, 2020 - Ewing sarcoma (ES) and peripheral primitive neuroectodermal tumor (PNET), Both entities that currently comprise the same spectrum of neoplastic diseases known as the Ewing sarcoma family of tumors (EFT), were originally described as distinct clini...

Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare Diseases
https://clinicaltrials.gov/ct2/show/NCT00001686

Sep 10th, 2020 - Background: Children and adults are referred to the Pediatric Oncology Branch (POB) for possible enrollment in clinical protocols for the treatment of cancer or other rare diseases. While some children are not eligible for a specific protocol, the...

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News  9 results

Blood-Brain-Barrier Therapy for CNS Tumors May Have Lasting Effect on Vision
https://www.medscape.com/viewarticle/942415

Dec 16th, 2020 - NEW YORK (Reuters Health) - Osmotic blood-brain-barrier disruption (BBBD) therapy, which increases the penetration of chemotherapeutics into malignant tumors of the central nervous system (CNS), may also affect sight, researchers say. "Osmotic blo...

Novel Agents Aimed at Disrupting Cancer Metabolism Gain Ground
https://www.onclive.com/view/novel-agents-aimed-at-disrupting-cancer-metabolism-gain-ground

Dec 5th, 2020 - Almost a century ago, Otto Warburg, MD, PhD, demonstrated that cancer cells prefer to obtain energy via glycolysis, taking in large amounts of glucose and producing lactic acid at high levels, even in the presence of oxygen and healthy mitochondri...

Chemoradiation and Radiation Produced Similar Outcomes in Extremity Soft Tissue Sarcoma
https://www.onclive.com/view/radiation-and-radiation-produced-similar-outcomes-in-extremity-soft-tissue-sarcoma

Nov 13th, 2020 - Researchers at Istanbul University Institute of Oncology have concluded that patients with high-risk extremity soft tissue sarcoma have similar 3-year outcomes whether they are assigned to neoadjuvant sequential chemoradiotherapy or radiation alon...

Primitive Neuroectodermal Tumor of the Pancreas in Adults; A Rare and Aggressive Malignancy
https://www.mdedge.com/fedprac/article/227899/oncology/primitive-neuroectodermal-tumor-pancreas-adults-rare-and-aggressive
Prashanth Ashok Kumar, Ali Wazir et. al.

Sep 2nd, 2020 - INTRODUCTION: Primitive neuroectodermal tumors (PNET) are highly aggressive malignancies composed of small round cells that are neuroectodermal in origin similar to Ewings Sarcoma. PNET of the pancreas is extremely rare with around 20 cases report.

CLTX-CAR T cells exhibit preclinical activity and move on to a clinical trial
https://www.mdedge.com/hematology-oncology/article/218418/cns/brain-cancer/cltx-car-t-cells-exhibit-preclinical-activity?channel=39313
Caleb Rans

Mar 4th, 2020 - Chlorotoxin (CLTX)-directed chimeric antigen receptor (CAR) T cells demonstrated activity against glioblastoma in a preclinical study and will soon be tested in a clinical trial. “We sought to develop a CAR T cell using chlorotoxin peptide as the.

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Patient Education  2 results see all →