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About 240 results

ALLMedicine™ Paraneoplastic Cerebellar Degeneration Center

Research & Reviews  90 results

The Discovery of Anti-Yo (Anti-PCA1) Antibody in Patients with Paraneoplastic Cerebella...
https://doi.org/10.1007/s12311-022-01446-9
Cerebellum (London, England); Greenlee JE, Brashear HR

Jul 27th, 2022 - Prior to 1982, ovarian and certain other cancers were known to have a rare complication of progressive cerebellar ataxia, a disorder characterized pathologically by severe-often total-obliteration of cerebellar Purkinje cells. However, the cause o...

Nodular Sclerosing Hodgkin Lymphoma With Paraneoplastic Cerebellar Degeneration
https://www.mdedge.com/fedprac/article/256291/hematologic-malignancies/nodular-sclerosing-hodgkin-lymphoma-paraneoplastic
LCDR Denise Teh, DO, LT Hunter Culp, MD et. al.

Jul 15th, 2022 - Paraneoplastic syndrome is a rare disorder involving manifestations of immune dysregulation triggered by malignancy. The immune system develops antibodies to the malignancy, which can cause cross reactivation with various tissues in the body, resu.

Autoimmune Cerebellar Ataxia: Etiology and Clinical Characteristics of a Case Series fr...
https://doi.org/10.1007/s12311-022-01412-5
Cerebellum (London, England); Liu M, Ren H et. al.

May 27th, 2022 - Autoimmune cerebellar ataxia (ACA) is an important and potentially treatable cause of sporadic cerebellar syndrome, but studies with large sample size are limited. This study reported a large ACA series in China and described its etiology and clin...

What is in the Neuromuscular Junction Literature?
https://doi.org/10.1097/CND.0000000000000403
Journal of Clinical Neuromuscular Disease; Al-Lahham T, Lacomis D

May 25th, 2022 - This update covers a number of treatment topics starting with Fc receptor inhibitors and the Federal Drug Administration approval of efgartigimod. Some uncertainties regarding the use of corticosteroids are addressed, namely the risk of exacerbati...

Paraneoplastic cerebellar degeneration with anti-Yo antibodies and an associated subman...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059384
BMC Neurology; Imai T, Shinohara K et. al.

May 4th, 2022 - As a debilitating syndrome, paraneoplastic cerebellar degeneration (PCD) remains challenging to treat. Further, anti-Yo antibody (directed against human cerebellar degeneration-related protein 2) detection in patients with PCD is associated with u...

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Clinicaltrials.gov  1 results

Immunotherapy and Paraneoplastic Neurological Syndromes
https://clinicaltrials.gov/ct2/show/NCT02343211

Nov 6th, 2017 - Paraneoplastic neurological syndromes (PNS) are remote effects of malignant neoplasia on neural tissue, not directly caused by mass lesions, metastases, infections, ischemia, coagulopathy, metabolic disruptions or treatment. The symptoms and signs...

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News  5 results

Nodular Sclerosing Hodgkin Lymphoma With Paraneoplastic Cerebellar Degeneration
https://www.mdedge.com/fedprac/article/256291/hematologic-malignancies/nodular-sclerosing-hodgkin-lymphoma-paraneoplastic
LCDR Denise Teh, DO, LT Hunter Culp, MD et. al.

Jul 15th, 2022 - Paraneoplastic syndrome is a rare disorder involving manifestations of immune dysregulation triggered by malignancy. The immune system develops antibodies to the malignancy, which can cause cross reactivation with various tissues in the body, resu.

Lambert-Eaton Myasthenic Syndrome and Merkel Cell Carcinoma
https://www.mdedge.com/dermatology/article/201596/rare-diseases/lambert-eaton-myasthenic-syndrome-and-merkel-cell-carcinoma/page/0/2?channel=285

May 24th, 2019 - Paraneoplastic Syndromes Associated With MCC Other paraneoplastic syndromes have been reported in association with MCC. A patient with brainstem encephalitis associated with MCC was reported in a trial of a novel immunotherapy for paraneoplastic n.

Anti-Yo Antibody-Mediated Paraneoplastic Cerebellar Degeneration in a Man With Esophageal Adenocarcinoma
https://www.medscape.com/viewarticle/458354_3

Aug 5th, 2003 - Discussion PCD is a paraneoplastic neurologic syndrome characterized by cerebellar dysfunction, typically presenting with ataxia, dysarthria, and intentional tremor. The onset may be abrupt, with symptoms developing over several days, or subacute,...

Anti-Yo Antibody-Mediated Paraneoplastic Cerebellar Degeneration in a Man With Esophageal Adenocarcinoma
https://www.medscape.com/viewarticle/458354

Aug 5th, 2003 - Abstract and Introduction Abstract We report a case of paraneoplastic cerebellar degeneration (PCD) associated with adenocarcinoma of the esophagus and anti-Yo antibodies in a male patient. The patient presented with progressive ataxia, dysarthria...

Anti-Yo Antibody-Mediated Paraneoplastic Cerebellar Degeneration in a Man With Esophageal Adenocarcinoma
https://www.medscape.com/viewarticle/458354_1

Aug 5th, 2003 - Abstract and Introduction Abstract We report a case of paraneoplastic cerebellar degeneration (PCD) associated with adenocarcinoma of the esophagus and anti-Yo antibodies in a male patient. The patient presented with progressive ataxia, dysarthria...

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