About 243 results

ALLMedicine™ Pediatric Medulloblastoma Center

Research & Reviews  93 results

MRI Radiogenomics of Pediatric Medulloblastoma: A Multicenter Study.
Radiology Zhang M, Wong SW et. al.

Apr 20th, 2022 - Background Radiogenomics of pediatric medulloblastoma (MB) offers an opportunity for MB risk stratification, which may aid therapeutic decision making, family counseling, and selection of patient groups suitable for targeted genetic analysis. Purp...

GABAA receptor agonist suppresses pediatric medulloblastoma progression by inhibiting P...
Molecular Therapy : the Journal of the American Society O... Kaushik I, Srivastava SK

Mar 26th, 2022 - The Sonic hedgehog-activated subgroup of medulloblastoma (SHH-MB) is one of the most common malignant pediatric brain tumors. Recent clinical studies and genomic databases indicate that GABAA receptor holds significant clinical relevance as a ther...

Clinical and molecular characterization of isolated M1 disease in pediatric medulloblas...
Journal of Neuro-oncology; Obrecht D, Mynarek M et. al.

Feb 23rd, 2022 - To evaluate the clinical impact of isolated spread of medulloblastoma cells into cerebrospinal fluid without additional macroscopic metastases (M1-only). The HIT-MED database was searched for pediatric patients with M1-only medulloblastoma diagnos...

Integration of immunohistochemistry, RNA sequencing, and multiplex ligation-dependent p...
Pediatric Blood & Cancer; Huang HY, Yu CH et. al.

Feb 5th, 2022 - Medulloblastoma (MB) is commonly classified into four molecular groups, that is, WNT, SHH, group 3, and group 4, for prognostic and therapeutic purposes. Here we applied immunohistochemistry (IHC) and RNA sequencing (RNA-seq) for the molecular cla...

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Clinicaltrials.gov  2 results

Social Cognition and Brain Integrity in Survivors of Pediatric Medulloblastoma

Oct 15th, 2021 - Comprehensive social-cognitive and behavioral data will be collected and structural and functional brain imaging will be completed in an attempt to determine if disruptions to brain integrity and function caused by prior treatment of medulloblasto...

A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma

Aug 27th, 2013 - The purpose of this study is to find a recommended dose level of LY2940680 that can be safely given to children with medulloblastoma or rhabdomyosarcoma that has returned or doesn't respond to initial treatment. The study will also explore the cha...

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News  2 results

A Win for Protons in Pediatric Brain Tumors

Dec 23rd, 2019 - Proton therapy for pediatric brain tumors led to significantly better longitudinal intelligence outcomes as compared with conventional radiation therapy, results of a matched-cohort study showed. With a median follow-up of 4 to 5 years, children w...

Proton Beam in Medulloblastoma: 'New Benchmark'

Feb 4th, 2016 - For children with medulloblastoma, proton-beam radiotherapy should be considered an "attractive alternative" to conventional radiotherapy, the authors of a new study conclude. Proton-beam therapy "is effective in decreasing many of the late side e...

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