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About 880 results

ALLMedicine™ Radiation Necrosis Center

Research & Reviews  339 results

Safety and efficacy of irradiation boost based on 18F-FET-PET in patients with newly di...
https://doi.org/10.1158/1078-0432.CCR-22-0171
Clinical Cancer Research : an Official Journal of the Ame... Harat M, Blok M et. al.

May 14th, 2022 - Dual timepoint FET-PET acquisition (10 and 60 minutes after FET injection) improves the definition of glioblastoma location and shape. Here we evaluated the safety and efficacy of simultaneous integrated boost (SIB) planned using dual FET-PET for ...

A deep neural network-based model predicting peritumoral edema after radiosurgery for m...
https://doi.org/10.1016/j.wneu.2022.04.125
World Neurosurgery; Kim KH, Jung S et. al.

May 9th, 2022 - Gamma Knife radiosurgery (GKS) is a promising treatment option for meningioma. However, the incidence of peritumoral edema (PTE) following GKS has been reported to be 7%-38%. This study aimed to develop a predictive model for post-GKS PTE using a ...

DSC Perfusion MRI-Derived Fractional Tumor Burden and Relative CBV Differentiate Tumor ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089266
AJNR. American Journal of Neuroradiology; Kuo F, Ng NN et. al.

Apr 29th, 2022 - Differentiation between tumor and radiation necrosis in patients with brain metastases treated with stereotactic radiosurgery is challenging. We hypothesized that MR perfusion and metabolic metrics can differentiate radiation necrosis from progres...

Single low-dose targeted bevacizumab infusion in adult patients with steroid-refractory...
https://doi.org/10.3171/2022.2.JNS212006
Journal of Neurosurgery; Dashti SR, Kadner RJ et. al.

Apr 16th, 2022 - There is an unmet need for safe and rapidly effective therapies for refractory brain radiation necrosis (RN). The aim of this prospective single-arm phase II trial was to evaluate the safety and efficacy of a single low-dose targeted bevacizumab i...

Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases
https://clinicaltrials.gov/ct2/show/NCT03680144

Apr 11th, 2022 - PRIMARY OBJECTIVE: I. To prospectively determine the sensitivity and specificity of dynamic susceptibility contrast (DSC)-MRI parameters in detecting tumor recurrence versus radiation necrosis for brain metastases treated with stereotactic radiosu...

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Clinicaltrials.gov  10 results

Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases
https://clinicaltrials.gov/ct2/show/NCT03680144

Apr 11th, 2022 - PRIMARY OBJECTIVE: I. To prospectively determine the sensitivity and specificity of dynamic susceptibility contrast (DSC)-MRI parameters in detecting tumor recurrence versus radiation necrosis for brain metastases treated with stereotactic radiosu...

Analyzing Preoperative Stereotactic Radiosurgery With Gamma Knife Icon for Brain Metastases
https://clinicaltrials.gov/ct2/show/NCT04545814

Mar 3rd, 2022 - INTERVENTION: Enrolled patients will receive stereotactic radiosurgery (SRS) to all metastases followed by surgical resection of resectable metastases within one to 10 days following SRS. Pathologic specimens will be analyzed, and the patient will...

MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas
https://clinicaltrials.gov/ct2/show/NCT04373720

Dec 22nd, 2021 - PRIMARY OBJECTIVES: I. To estimate the mean lesion stiffness in patients with radiation necrosis using magnetic resonance elastography (MRE). II. To estimate the mean lesion stiffness in patients with glioma recurrence using magnetic resonance ela...

Low-dose Intra-arterial Bevacizumab for Edema and Radiation Necrosis Therapeutic Intervention (LIBERTI)
https://clinicaltrials.gov/ct2/show/NCT02819479

Jun 28th, 2021 - BACKGROUND Radiation Necrosis: Stereotactic radiosurgery has become integral in treatment of brain tumors and arteriovenous malformations (AVM). In up to 10% of cases, this can lead to radiation necrosis (RN) with significant surrounding vasogenic...

Feasibility Study of 68Ga-PSMA PET-CT and 18F-FDOPA PET-CT in Glioblastoma's Patients
https://clinicaltrials.gov/ct2/show/NCT03903419

Oct 14th, 2020 - Gliomas are the most common primary intra-axial brain tumors arising from the glial cells. The reference treatment consists in a surgical removal followed by radiotherapy and chemotherapy (Temozolomide). Because of frequent recurrences after first...

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News  3 results

Radiation Therapy and Abscopal Effect in Melanoma Treatment
https://www.onclive.com/view/radiation-therapy-and-abscopal-effect-in-melanoma-treatment

Apr 2nd, 2021 - Transcript:Keith Flaherty, MD: I’ve been fascinated to watch, over the past five years, with the introduction of new effective systemic therapies, the way that radiation therapy and surgery are being reevaluated in terms of their role in patients ...

HSRT a Good Option for Resection Cavity of Brain Metastases
https://www.medpagetoday.com/hematologyoncology/braincancer/89132

Oct 15th, 2020 - Use of local hypofractionated stereotactic radiotherapy (HSRT) to the resection cavity in patients with brain metastases appeared to have a good risk-benefit profile with favorable local control and low risk of treatment-related adverse effects co...

FDA Alert on MR-Guided Laser Interstitial Thermal Therapy Devices
https://www.medscape.com/viewarticle/895688

Apr 25th, 2018 - There is a risk of tissue overheating owing to inaccurate magnetic resonance (MR) thermometry with MR-guided laser interstitial thermal therapy (MRgLITT) devices, the US Food and Drug Administration (FDA) said today in a safety communication. The ...

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