ALLMedicine™ Radiation Necrosis Center

May 14th, 2022 - Dual timepoint FET-PET acquisition (10 and 60 minutes after FET injection) improves the definition of glioblastoma location and shape. Here we evaluated the safety and efficacy of simultaneous integrated boost (SIB) planned using dual FET-PET for ...

May 9th, 2022 - Gamma Knife radiosurgery (GKS) is a promising treatment option for meningioma. However, the incidence of peritumoral edema (PTE) following GKS has been reported to be 7%-38%. This study aimed to develop a predictive model for post-GKS PTE using a ...

Apr 29th, 2022 - Differentiation between tumor and radiation necrosis in patients with brain metastases treated with stereotactic radiosurgery is challenging. We hypothesized that MR perfusion and metabolic metrics can differentiate radiation necrosis from progres...

Apr 16th, 2022 - There is an unmet need for safe and rapidly effective therapies for refractory brain radiation necrosis (RN). The aim of this prospective single-arm phase II trial was to evaluate the safety and efficacy of a single low-dose targeted bevacizumab i...

Apr 11th, 2022 - PRIMARY OBJECTIVE: I. To prospectively determine the sensitivity and specificity of dynamic susceptibility contrast (DSC)-MRI parameters in detecting tumor recurrence versus radiation necrosis for brain metastases treated with stereotactic radiosu...

Apr 11th, 2022 - PRIMARY OBJECTIVE: I. To prospectively determine the sensitivity and specificity of dynamic susceptibility contrast (DSC)-MRI parameters in detecting tumor recurrence versus radiation necrosis for brain metastases treated with stereotactic radiosu...

Mar 3rd, 2022 - INTERVENTION: Enrolled patients will receive stereotactic radiosurgery (SRS) to all metastases followed by surgical resection of resectable metastases within one to 10 days following SRS. Pathologic specimens will be analyzed, and the patient will...

Dec 22nd, 2021 - PRIMARY OBJECTIVES: I. To estimate the mean lesion stiffness in patients with radiation necrosis using magnetic resonance elastography (MRE). II. To estimate the mean lesion stiffness in patients with glioma recurrence using magnetic resonance ela...

Jun 28th, 2021 - BACKGROUND Radiation Necrosis: Stereotactic radiosurgery has become integral in treatment of brain tumors and arteriovenous malformations (AVM). In up to 10% of cases, this can lead to radiation necrosis (RN) with significant surrounding vasogenic...

Oct 14th, 2020 - Gliomas are the most common primary intra-axial brain tumors arising from the glial cells. The reference treatment consists in a surgical removal followed by radiotherapy and chemotherapy (Temozolomide). Because of frequent recurrences after first...

Apr 2nd, 2021 - Transcript:Keith Flaherty, MD: I’ve been fascinated to watch, over the past five years, with the introduction of new effective systemic therapies, the way that radiation therapy and surgery are being reevaluated in terms of their role in patients ...

Oct 15th, 2020 - Use of local hypofractionated stereotactic radiotherapy (HSRT) to the resection cavity in patients with brain metastases appeared to have a good risk-benefit profile with favorable local control and low risk of treatment-related adverse effects co...

Apr 25th, 2018 - There is a risk of tissue overheating owing to inaccurate magnetic resonance (MR) thermometry with MR-guided laser interstitial thermal therapy (MRgLITT) devices, the US Food and Drug Administration (FDA) said today in a safety communication. The ...