About 26,778 results

ALLMedicine™ Renal Cell Carcinoma Center

Research & Reviews  9,066 results

Novel Diagnostic Value of Driver Gene Transcription Signatures to Characterise Clear Ce...
Pathology Oncology Research : POR; Ujfaludi Z, Kuthi L et. al.

May 20th, 2022 - Routine molecular tumour diagnostics are augmented by DNA-based qualitative and quantitative molecular techniques detecting mutations of DNA. However, in the past decade, it has been unravelled that the phenotype of cancer, as it's an extremely co...

Multiple organ dysfunction due to inferior vena cava thrombosis diagnosed by point-of-c...
Journal of Clinical Ultrasound : JCU; Cheong I

May 19th, 2022 - We describe the case of a 75-years-old woman with history of left renal cell carcinoma that presented multiple organ dysfunction due to IVCT diagnosed by point-of-care ultrasound (POCUS) in the intensive care unit (ICU).

Impact of Metastasectomy on Cancer Specific and Overall Survival in Metastatic Renal Ce...
Clinical Genitourinary Cancer; Meagher MF, Mir MC et. al.

May 19th, 2022 - Treatment paradigms for management of metastatic renal cell carcinoma (mRCC) are evolving. We examined impact of surgical metastasectomy on survival across in mRCC stratified by risk-group. Multicenter retrospective analysis from the Registry of M...

Special issue "The advance of solid tumor research in China": Multi-omics analysis base...
International Journal of Cancer; Tian X, Wang Y et. al.

May 18th, 2022 - In clear cell renal cell carcinoma (ccRCC), glycolysis is enhanced mainly because of the increased expression of key enzymes in glycolysis. Hence, the discovery of new molecular biomarkers for glycolysis may help guide and establish a precise syst...

Isolated soft tissue mass of the finger as the first presentation of oligometastatic re...
BMJ Case Reports; Hopkins DT, Waters D et. al.

May 18th, 2022 - A man in his 70s was referred to plastic surgery with a suspected foreign body in the pulp of his right index finger. An excisional biopsy was performed for a presumed foreign body granuloma. Histology revealed metastatic renal cell carcinoma (mRC...

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Guidelines  23 results

ACR Appropriateness Criteria® Post-Treatment Follow-up and Active Surveillance of Clini...
Journal of the American College of Radiology : JACR; , Purysko AS et. al.

May 14th, 2022 - Renal cell carcinoma (RCC) accounts for most malignant renal tumors and is considered the most lethal of all urologic cancers. For follow-up of patients with treated or untreated RCC and those with neoplasms suspected to represent RCC, radiologic ...

Kidney Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
Journal of the National Comprehensive Cancer Network : JN... Motzer RJ, Jonasch E et. al.

Jan 7th, 2022 - The NCCN Guidelines for Kidney Cancer focus on the screening, diagnosis, staging, treatment, and management of renal cell carcinoma (RCC). Patients with relapsed or stage IV RCC typically undergo surgery and/or receive systemic therapy. Tumor hist...

Evolving Patterns of Metastasis in Renal Cell Carcinoma: Do We Need to Perform Routine Bone Imaging?
Journal of Kidney Cancer and VHL; Lin J

Oct 13th, 2021 - Advance diagnostic and treatment modalities have improved outcomes for renal cell carcinoma (RCC) patients, but the prognosis for those with metastatic disease (mRCC) remains poor. As given metastatic distribution is critical in guiding treatment ...

Germline Variants Identified in Patients with Early-onset Renal Cell Carcinoma Referred for Germline Genetic Testing
European Urology Oncology; Truong H

Oct 12th, 2021 - Despite guidelines recommending genetic counseling for patients with early-onset renal cell carcinoma (RCC), studies interrogating the spectrum of germline mutations and clinical associations in patients with early-onset RCC are lacking.

ESMO Clinical Practice Guideline update on the use of immunotherapy in early stage and ...
Annals of Oncology : Official Journal of the European Soc... Powles T, Albiges L et. al.

Oct 2nd, 2021 - ESMO Clinical Practice Guideline update on the use of immunotherapy in early stage and advanced renal cell carcinoma.|2021|Powles T,Albiges L,Bex A,Grünwald V,Porta C,|drug therapy,drug therapy,

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Drugs  42 results see all →

Clinicaltrials.gov  371 results

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

May 13th, 2022 - Background: Rare histological variants of the GU tract include bladder/urachal adenocarcinoma, squamous cell carcinoma, and small cell carcinoma; variants of urothelial carcinoma including plasmacytoid, sarcomatoid; renal tumors including sarcomat...

Hereditary Leiomyomatosis Renal Cell Cancer - Study of the Genetic Cause and the Predisposition to Renal Cancer

May 13th, 2022 - Background: Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare autosomal dominantly inherited disorder which confers susceptibility to develop cutaneous and uterine leiomyomas and renal cell carcinoma. HLRCC is caused by mutations i...

BMS-936558 (MDX-1106) In Subjects With Advanced/Metastatic Clear-Cell Renal Cell Carcinoma (RCC)

May 12th, 2022 - The purpose of this study is to measure how active BMS-936558 (nivolumab) is against Renal Cell Carcinoma (RCC) as measured by the disease not progressing and whether a dose response relationship exists.

Study of Pembrolizumab (MK-3475) Monotherapy in Locally Advanced/Metastatic Renal Cell Carcinoma (MK-3475-427/KEYNOTE-427)

May 11th, 2022 - The purpose of this study is to assess the safety and efficacy of monotherapy pembrolizumab (MK-3475) in participants with renal cell carcinoma (RCC). There will be two cohorts in this study: Cohort A will consist of participants with clear cell (...

A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma

May 11th, 2022 - Patients with localized and non-metastatic Renal Cell Carcinoma (RCC) represent an "at-need" population who would benefit from immunotherapy earlier in their disease course with a programmed cell death protein 1(PD-1) therapy combined with a secon...

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News  1,205 results

FDA Rejects More China Drugs; Clue to Uterine Ca Disparity; Cancer-Vax Controversy

May 6th, 2022 - China-based Hutchmed announced receipt of a complete response letter from the FDA, stating that the agency cannot approve the tyrosine kinase inhibitor surufatinib for advanced neuroendocrine tumors without support from a multiregional clinical tr...

Ongoing Clinical Trials in the Neoadjuvant Setting in RCC

May 4th, 2022 - Tian Zhang, MD: Dr Barata, can you provide a brief overview of some ongoing neoadjuvant therapy trials? In particular, we saw some data from one of the first IO [immunotherapy]/VEGF combination trials to report out, avelumab and axitinib, at ASCO ...

Renal Cell Carcinoma: Future Directions in Care

May 2nd, 2022 - Transcript: Robert J. Motzer, MD: Two last quick points for you. Cabozantinib is 1 of our main go-to drugs for RCC [renal cell carcinoma]. It’s been proposed to be particularly effective for bone metastases, right? There were recent data for cabo...

Adverse Events in IO-IO Combination Treatment Regimens for Advanced RCC

May 2nd, 2022 - Arnab Basu, MD: In your experience, what are some of the commonly observed adverse events in this IO [immunotherapy]/IO combination therapy regimen, and how do you manage those? Shawnta Anakwah, MD: Typically, the ones that I’ve seen have been ra...

Microbiota Modulation Offers Hope of Expanding the Benefits of Immunotherapy

Apr 28th, 2022 - Although the microorganisms colonizing our bodies have long been linked to human health and various disease states, an understanding of the potential impact of the microbiota on cancer has just begun to emerge in the past 20 years. Novel strategie...

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Patient Education  4 results see all →