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About 20,074 results

ALLMedicine™ Sarcomas Center

Research & Reviews  9,657 results

The impact of pathological fractures on surgery, morbidity, functional and oncological ...
https://doi.org/10.1016/j.injury.2021.04.062
Injury Saglam F, Baysal Ö et. al.

May 17th, 2021 - Background Although rare, pathological fractures may occur in primary bone sarcomas. There have been studies reporting that such patients have a poorer prognosis than those without a pathological fracture. This study investigates the impact of pat...

Doxorubicin-Dexrazoxane from Day 1 for Soft-tissue Sarcomas: The Road to Cardioprotection.
https://doi.org/10.1158/1078-0432.CCR-21-1376
Clinical Cancer Research : an Official Journal of the Ame... Benjamin RS, Minotti G

May 15th, 2021 - Doxorubicin cardiac toxicity is widely misunderstood, largely preventable, and starts with the first dose. This paper reviews the history of doxorubicin cardiac toxicity and strategies for minimizing it. Dexrazoxane cardioprotection can safely be ...

Endometrial Carcinoma as the Presenting Malignancy in a Teenager With a Pathogenic TP53...
https://doi.org/10.1097/PGP.0000000000000792
International Journal of Gynecological Pathology : Offici... Irshaid L, Clark M et. al.

May 14th, 2021 - Patients with germline TP53 mutations are characterized by the occurrence of multiple early-onset malignancies. The characteristic syndrome is Li-Fraumeni syndrome (OMIM # 151623), an autosomal dominant disorder typified by premenopausal breast ca...

Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecula...
https://doi.org/10.1038/s41379-021-00818-6 10.1097/00000478-200606000-00004 10.1097/00000478-199802000-00002 10.1097/00000478-199703000-00002 10.1097/PAS.0b013e3181d74bdb 10.1097/PAS.0b013e3181a6cd33 10.1097/PAS.0b013e31826c1761 10.1097/01.ju.0000134580.71261.57 10.1038/modpathol.2013.99 10.1016/j.humpath.2017.12.004 10.5858/arpa.2016-0527-OA 10.1172/jci.insight.87062 10.1093/nar/gku1211 10.1038/s41379-018-0091-x 10.1002/gcc.22690 10.1093/nar/gkv1234 10.1093/bioinformatics/btv710 10.1002/gcc.22083 10.1038/ng.2509 10.1073/pnas.101132598 10.1097/00000478-200402000-00010 10.1002/gcc.22907 10.1097/PAS.0000000000001030 10.1097/PAS.0000000000001055 10.1038/s41379-018-0184-6 10.1097/PAS.0000000000000675 10.1097/PAS.0000000000001377 10.1016/j.cllc.2019.09.004 10.1002/gcc.22671 10.1097/PAS.0000000000000591 10.1111/his.14023 10.1097/PAS.0000000000000965 10.1038/modpathol.2011.98 10.18632/oncotarget.26075 10.1016/j.euf.2019.05.012 10.1002/gcc.10035 10.1038/ng.2617 10.1053/j.seminoncol.2020.02.009 10.1002/ijc.27800 10.1158/1078-0432.CCR-15-2631 10.1158/0008-5472.CAN-06-0140 10.1126/scitranslmed.aac8228 10.1158/1535-7163.MCT-10-0893 10.1016/j.ebiom.2020.102971 10.1158/0008-5472.CAN-10-1543 10.1097/PAS.0b013e3180581fff 10.1097/PAS.0000000000000184 10.1002/gcc.2870100203 10.1016/j.humpath.2016.03.011 10.1016/j.pathol.2020.06.004 10.1016/j.jmoldx.2016.10.002
Modern Pathology : an Official Journal of the United Stat... Acosta AM, Sholl LM et. al.

May 14th, 2021 - Tumors of purported specialized prostatic stromal origin comprise prostatic stromal sarcomas (PSS) and stromal tumors of uncertain malignant potential (STUMP). Prior studies have described their clinicopathologic characteristics, but the molecular...

Sarcomas with Sclerotic Epithelioid Phenotype Harboring Novel EWSR1-SSX1 Fusions.
https://doi.org/10.1002/gcc.22970
Genes, Chromosomes & Cancer; Antonescu CR, Rosenberg AE et. al.

May 14th, 2021 - Undifferentiated sarcomas remain difficult to classify. Despite the remarkable advances in sarcoma classification made by the increased application of RNA sequencing in clinical practice, the unexpected result of a novel gene fusion raises further...

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Guidelines  33 results

Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatme...
https://doi.org/10.1093/annonc/mdy310
Annals of Oncology : Official Journal of the European Soc... Casali PG, Bielack S et. al.

Oct 4th, 2018 - Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2018|Casali PG,Bielack S,Abecassis N,Aro HT,Bauer S,|methods,standards,standards,therapeutic use,diagnosis,epidemiology,pathology,therapy,diag...

Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment an...
https://academic.oup.com/annonc/article/29/Supplement_4/iv79/5115250
Casali, P

Sep 30th, 2018 - Primary bone tumours are rare, accounting for < 0. 2% of malignant neoplasms registered in the EUROCARE (European Cancer Registry based study on survival and care of cancer patients) database [1].

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagno...
https://doi.org/10.1093/annonc/mdy096
Annals of Oncology : Official Journal of the European Soc... Casali PG, Abecassis N et. al.

May 30th, 2018 - Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.|2018|Casali PG,Abecassis N,Aro HT,Bauer S,Biagini R,|methods,standards,standards,therapeutic use,diagnostic imaging,pathology,meth...

Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, ...
https://academic.oup.com/annonc/advance-article/doi/10.1093/annonc/mdy096/5004451
Casali, P. G.

May 27th, 2018 - Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular subsets, characterised by a low to very low incidence in all populations. The majority of sarcomas arise from the soft tissue (close to 75%), with ?15% gast.

Soft Tissue Sarcoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology
http://www.jnccn.org/content/16/5/536.full
Mehren, M.

Apr 30th, 2018 - Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues.

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Drugs  33 results see all →

Clinicaltrials.gov  10,015 results

The impact of pathological fractures on surgery, morbidity, functional and oncological ...
https://doi.org/10.1016/j.injury.2021.04.062
Injury Saglam F, Baysal Ö et. al.

May 17th, 2021 - Background Although rare, pathological fractures may occur in primary bone sarcomas. There have been studies reporting that such patients have a poorer prognosis than those without a pathological fracture. This study investigates the impact of pat...

Doxorubicin-Dexrazoxane from Day 1 for Soft-tissue Sarcomas: The Road to Cardioprotection.
https://doi.org/10.1158/1078-0432.CCR-21-1376
Clinical Cancer Research : an Official Journal of the Ame... Benjamin RS, Minotti G

May 15th, 2021 - Doxorubicin cardiac toxicity is widely misunderstood, largely preventable, and starts with the first dose. This paper reviews the history of doxorubicin cardiac toxicity and strategies for minimizing it. Dexrazoxane cardioprotection can safely be ...

Endometrial Carcinoma as the Presenting Malignancy in a Teenager With a Pathogenic TP53...
https://doi.org/10.1097/PGP.0000000000000792
International Journal of Gynecological Pathology : Offici... Irshaid L, Clark M et. al.

May 14th, 2021 - Patients with germline TP53 mutations are characterized by the occurrence of multiple early-onset malignancies. The characteristic syndrome is Li-Fraumeni syndrome (OMIM # 151623), an autosomal dominant disorder typified by premenopausal breast ca...

Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecula...
https://doi.org/10.1038/s41379-021-00818-6 10.1097/00000478-200606000-00004 10.1097/00000478-199802000-00002 10.1097/00000478-199703000-00002 10.1097/PAS.0b013e3181d74bdb 10.1097/PAS.0b013e3181a6cd33 10.1097/PAS.0b013e31826c1761 10.1097/01.ju.0000134580.71261.57 10.1038/modpathol.2013.99 10.1016/j.humpath.2017.12.004 10.5858/arpa.2016-0527-OA 10.1172/jci.insight.87062 10.1093/nar/gku1211 10.1038/s41379-018-0091-x 10.1002/gcc.22690 10.1093/nar/gkv1234 10.1093/bioinformatics/btv710 10.1002/gcc.22083 10.1038/ng.2509 10.1073/pnas.101132598 10.1097/00000478-200402000-00010 10.1002/gcc.22907 10.1097/PAS.0000000000001030 10.1097/PAS.0000000000001055 10.1038/s41379-018-0184-6 10.1097/PAS.0000000000000675 10.1097/PAS.0000000000001377 10.1016/j.cllc.2019.09.004 10.1002/gcc.22671 10.1097/PAS.0000000000000591 10.1111/his.14023 10.1097/PAS.0000000000000965 10.1038/modpathol.2011.98 10.18632/oncotarget.26075 10.1016/j.euf.2019.05.012 10.1002/gcc.10035 10.1038/ng.2617 10.1053/j.seminoncol.2020.02.009 10.1002/ijc.27800 10.1158/1078-0432.CCR-15-2631 10.1158/0008-5472.CAN-06-0140 10.1126/scitranslmed.aac8228 10.1158/1535-7163.MCT-10-0893 10.1016/j.ebiom.2020.102971 10.1158/0008-5472.CAN-10-1543 10.1097/PAS.0b013e3180581fff 10.1097/PAS.0000000000000184 10.1002/gcc.2870100203 10.1016/j.humpath.2016.03.011 10.1016/j.pathol.2020.06.004 10.1016/j.jmoldx.2016.10.002
Modern Pathology : an Official Journal of the United Stat... Acosta AM, Sholl LM et. al.

May 14th, 2021 - Tumors of purported specialized prostatic stromal origin comprise prostatic stromal sarcomas (PSS) and stromal tumors of uncertain malignant potential (STUMP). Prior studies have described their clinicopathologic characteristics, but the molecular...

Sarcomas with Sclerotic Epithelioid Phenotype Harboring Novel EWSR1-SSX1 Fusions.
https://doi.org/10.1002/gcc.22970
Genes, Chromosomes & Cancer; Antonescu CR, Rosenberg AE et. al.

May 14th, 2021 - Undifferentiated sarcomas remain difficult to classify. Despite the remarkable advances in sarcoma classification made by the increased application of RNA sequencing in clinical practice, the unexpected result of a novel gene fusion raises further...

see more →

News  307 results

Fast Five Quiz: Thyroid Cancer Practice Essentials
https://reference.medscape.com/viewarticle/938275

Sep 30th, 2020 - Although benign thyroid disease is relatively common, thyroid cancer occurs far less frequently. Most thyroid cancers are papillary carcinomas, with follicular carcinomas, medullary thyroid carcinomas, and anaplastic carcinomas accounting for far ...

Pembrolizumab Shows Activity in Select Rare Sarcomas
https://www.staging.medscape.com/viewarticle/937967

Sep 23rd, 2020 - Sarcomas are rare malignancies, and effective therapies, apart from surgery and radiotherapy, are largely limited to chemotherapy and a handful of targeted agents. But a few rare sarcoma subtypes may respond to therapy with the immune checkpoint i...

Pembrolizumab Shows Activity in Select Rare Sarcomas
https://www.medscape.com/viewarticle/937967

Sep 23rd, 2020 - Sarcomas are rare malignancies, and effective therapies, apart from surgery and radiotherapy, are largely limited to chemotherapy and a handful of targeted agents. But a few rare sarcoma subtypes may respond to therapy with the immune checkpoint i...

Becoming the paradigm for clinical trial enrollment
https://www.mdedge.com/sarcomajournal/article/214255/becoming-paradigm-clinical-trial-enrollment
William D. Tap, MD

Dec 13th, 2019 - The previous issue of The Sarcoma Journal focused on findings from numerous clinical trials in sarcomas of various histologies presented at ASCO’s annual meeting. This issue features a study on enrollment issues that surround clinical trials in sa.

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Patient Education  29 results see all →