ALLMedicine™ Actinic Keratosis Center

Jul 25th, 2021 - Cutaneous squamous cell carcinoma (cSCC) often follows actinic keratosis (AK) and is the second most common skin cancer worldwide. To reduce metastasis risk, it is important to diagnose and treat cSCC early. This study aimed to identify hub genes ...

Jul 8th, 2021 - The role of immune cells and PD-L1 in cutaneous squamous carcinogenesis is unclear. This study examines T-cell populations, Langerhans cells (LCs) and PD-L1 in invasive squamous cell carcinoma (inSCC), adjacent precursors and normal skin (NS) to i...

Jul 3rd, 2021 - Treating actinic keratosis (AK) and photodamaged skin is critical to reduce the risk of progression to skin cancer. Laser resurfacing for AK treatment is available as either lesion-directed or field therapy. Laser resurfacing removes the superfici...

Jun 26th, 2021 - Most cutaneous squamous cell carcinomas (cSCCs) arise from actinic keratoses (AKs), making these premalignant lesions attractive targets for therapeutic intervention before transformation. In a new article of the Journal of Investigative Dermatolo...

Jun 20th, 2021 - Chronic sun damage in the background is common in pigmented actinic keratoses and Bowen's disease (pAK/BD). While explainable artificial intelligence (AI) demonstrated increased background attention for pAK/BD, humans frequently miss this clue in ...

Dec 14th, 2017 - Actinic keratoses (AK) arise on sun-exposed regions of the skin. If left untreated, AK may progress to invasive squamous cell carcinoma (SCC), although the rate of progression is low. A practical treatment algorithm for the treatment of AK in stan...

Jan 18th, 2017 - British Association of Dermatologists' guidelines for the care of patients with actinic keratosis 2017.|2017|de Berker D,McGregor JM,Mohd Mustapa MF,Exton LS,Hughes BR,|methods,methods,therapeutic use,therapeutic use,diagnosis,prevention & control...

Sep 16th, 2015 - Actinic keratosis (AK) is a frequent health condition attributable to chronic exposure to ultraviolet radiation. Several treatment options are available and evidence based guidelines are missing. The goal of these evidence- and consensus-based gui...

Mar 13th, 2014 - Actinic keratoses (AK) are common photo-induced cutaneous lesions that may progress to invasive squamous-cell carcinoma and serve as a risk marker for skin cancer. Although numerous studies present the various therapeutic options for AK, publicati...

Mar 18th, 2020 - To compare the safety and efficacy profiles of 5-FU Cream with Efudex® (5-FU) Cream, and to demonstrate the superior efficacy of the two active formulations over that of the Vehicle Control Cream, in the treatment of actinic keratosis.

Jan 14th, 2020 - Picato® (ingenol mebutate) gel is the first and only ingenol mebutate product approved by the Food and Drug Administration (FDA) in 2012 for the topical treatment of AKs on the face and scalp (0.015% formulation) and on the trunk and extremities (...

Dec 18th, 2019 - The incidence of non-melanoma skin cancers, due to increased ultraviolet (UV) exposure, has increased by 300% over the past 2 decades. The innovative UV sensor, Shade, is designed to help people manage their UV exposure by quantifying their UV exp...

Dec 13th, 2019 - Picato® (ingenol mebutate) gel is a new topical therapy for Actinic Keratosis (AK) in adults which was approved by the Korean Ministry of Food and Drug Safety (MFDS) in December 2013. For AK in face or scalp the 0.015 percent gel is approved to be...

Oct 17th, 2019 - This study will be a double-blinded, multicenter, activity, and safety study of KX2-391 Ointment administered topically to the face or scalp of subjects with actinic keratosis. The study consists of Screening, Treatment, Follow-up, and Recurrence ...

May 20th, 2021 - Combined reflectance confocal microscopy–optical coherence tomography is a noninvasive tool that could prove useful in the detection of squamous cell carcinoma (SCC) and distinguishing SCC in-situ and actinic keratosis (AK) from invasive SCC, resu...

May 10th, 2021 - New guidelines from the American Academy of Dermatology strongly recommend the use of either 5-fluorouracil (5-FU) or imiquimod for the field treatment of actinic keratosis (AK). They also conditionally recommend the use of photodynamic therapy (P...

Feb 11th, 2021 - NEW YORK (Reuters Health) - Just five treatments with an experimental ointment over five days were able to completely clear actinic keratosis lesions in half of all volunteers within two months, although one year after treatment the lesions had re...

Aug 17th, 2020 - (Reuters Health) - Skin diseases are highly prevalent among adults aged 70 years and older, with 75.7% of people in this age range reporting at least one skin disease requiring treatment or follow-up, a study in Finland suggests. Researchers exami...

Aug 17th, 2020 - (Reuters Health) - Skin diseases are highly prevalent among adults aged 70 years and older, with 75.7% of people in this age range reporting at least one skin disease requiring treatment or follow-up, a study in Finland suggests. Researchers exami...