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About 2,095 results

ALLMedicine™ Actinic Keratosis Center

Research & Reviews  650 results

Seven key hub genes identified by gene co-expression network in cutaneous squamous cell...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8306372
BMC Cancer; Chen H, Yang J et. al.

Jul 25th, 2021 - Cutaneous squamous cell carcinoma (cSCC) often follows actinic keratosis (AK) and is the second most common skin cancer worldwide. To reduce metastasis risk, it is important to diagnose and treat cSCC early. This study aimed to identify hub genes ...

PD-L1 Expression, T-lymphocyte Subpopulations and Langerhans Cells in Cutaneous Squamou...
https://doi.org/10.21873/anticanres.15131
Anticancer Research; Stravodimou A, Tzelepi V et. al.

Jul 8th, 2021 - The role of immune cells and PD-L1 in cutaneous squamous carcinogenesis is unclear. This study examines T-cell populations, Langerhans cells (LCs) and PD-L1 in invasive squamous cell carcinoma (inSCC), adjacent precursors and normal skin (NS) to i...

Laser Resurfacing Monotherapy for the Treatment of Actinic Keratosis.
https://doi.org/10.1177/12034754211027515
Journal of Cutaneous Medicine and Surgery; Tai F, Shah M et. al.

Jul 3rd, 2021 - Treating actinic keratosis (AK) and photodamaged skin is critical to reduce the risk of progression to skin cancer. Laser resurfacing for AK treatment is available as either lesion-directed or field therapy. Laser resurfacing removes the superfici...

Clarifying Progress on the Genomic Landscape of Actinic Keratosis.
https://doi.org/10.1016/j.jid.2021.02.761
The Journal of Investigative Dermatology; Hedberg M, Seykora JT

Jun 26th, 2021 - Most cutaneous squamous cell carcinomas (cSCCs) arise from actinic keratoses (AKs), making these premalignant lesions attractive targets for therapeutic intervention before transformation. In a new article of the Journal of Investigative Dermatolo...

Perilesional sun damage as a diagnostic clue for pigmented actinic keratosis and Bowen'...
https://doi.org/10.1111/jdv.17464
Journal of the European Academy of Dermatology and Venere... Weber P, Sinz C et. al.

Jun 20th, 2021 - Chronic sun damage in the background is common in pigmented actinic keratoses and Bowen's disease (pAK/BD). While explainable artificial intelligence (AI) demonstrated increased background attention for pAK/BD, humans frequently miss this clue in ...

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Guidelines  4 results

Management of actinic keratosis at specific body sites in patients at high risk of carc...
https://doi.org/10.1111/jdv.14753
Journal of the European Academy of Dermatology and Venere... Richard MA, Amici JM et. al.

Dec 14th, 2017 - Actinic keratoses (AK) arise on sun-exposed regions of the skin. If left untreated, AK may progress to invasive squamous cell carcinoma (SCC), although the rate of progression is low. A practical treatment algorithm for the treatment of AK in stan...

British Association of Dermatologists' guidelines for the care of patients with actinic...
https://doi.org/10.1111/bjd.15107
The British Journal of Dermatology; de Berker D, McGregor JM et. al.

Jan 18th, 2017 - British Association of Dermatologists' guidelines for the care of patients with actinic keratosis 2017.|2017|de Berker D,McGregor JM,Mohd Mustapa MF,Exton LS,Hughes BR,|methods,methods,therapeutic use,therapeutic use,diagnosis,prevention & control...

Evidence- and consensus-based (S3) Guidelines for the Treatment of Actinic Keratosis - ...
https://doi.org/10.1111/jdv.13180
Journal of the European Academy of Dermatology and Venere... Werner RN, Stockfleth E et. al.

Sep 16th, 2015 - Actinic keratosis (AK) is a frequent health condition attributable to chronic exposure to ultraviolet radiation. Several treatment options are available and evidence based guidelines are missing. The goal of these evidence- and consensus-based gui...

Management of actinic keratosis: a practical report and treatment algorithm from AKTeam...
https://doi.org/10.1111/jdv.12434
Journal of the European Academy of Dermatology and Venere... Dréno B, Amici JM et. al.

Mar 13th, 2014 - Actinic keratoses (AK) are common photo-induced cutaneous lesions that may progress to invasive squamous-cell carcinoma and serve as a risk marker for skin cancer. Although numerous studies present the various therapeutic options for AK, publicati...

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Drugs  8 results see all →

Clinicaltrials.gov  74 results

Bioequivalence Study to Compare Sol-Gel Technologies' 5-FU Cream With Efudex® (5-FU) Cream
https://clinicaltrials.gov/ct2/show/NCT03727074

Mar 18th, 2020 - To compare the safety and efficacy profiles of 5-FU Cream with Efudex® (5-FU) Cream, and to demonstrate the superior efficacy of the two active formulations over that of the Vehicle Control Cream, in the treatment of actinic keratosis.

An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis
https://clinicaltrials.gov/ct2/show/NCT03200912

Jan 14th, 2020 - Picato® (ingenol mebutate) gel is the first and only ingenol mebutate product approved by the Food and Drug Administration (FDA) in 2012 for the topical treatment of AKs on the face and scalp (0.015% formulation) and on the trunk and extremities (...

Validation of SHADE a Mobile Technology for Monitoring of Ultraviolet Exposure
https://clinicaltrials.gov/ct2/show/NCT03315286

Dec 18th, 2019 - The incidence of non-melanoma skin cancers, due to increased ultraviolet (UV) exposure, has increased by 300% over the past 2 decades. The innovative UV sensor, Shade, is designed to help people manage their UV exposure by quantifying their UV exp...

PMS to Evaluate the Safety and Efficacy of Picato® Gel
https://clinicaltrials.gov/ct2/show/NCT02421471

Dec 13th, 2019 - Picato® (ingenol mebutate) gel is a new topical therapy for Actinic Keratosis (AK) in adults which was approved by the Korean Ministry of Food and Drug Safety (MFDS) in December 2013. For AK in face or scalp the 0.015 percent gel is approved to be...

A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp
https://clinicaltrials.gov/ct2/show/NCT03285477

Oct 17th, 2019 - This study will be a double-blinded, multicenter, activity, and safety study of KX2-391 Ointment administered topically to the face or scalp of subjects with actinic keratosis. The study consists of Screening, Treatment, Follow-up, and Recurrence ...

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News  98 results

Combined Imaging Methods Found to Enhance Detection of SCC
https://www.medscape.com/viewarticle/951575

May 20th, 2021 - Combined reflectance confocal microscopy–optical coherence tomography is a noninvasive tool that could prove useful in the detection of squamous cell carcinoma (SCC) and distinguishing SCC in-situ and actinic keratosis (AK) from invasive SCC, resu...

AAD Unveils New Guidelines for Actinic Keratosis Management
https://www.medscape.com/viewarticle/950849

May 10th, 2021 - New guidelines from the American Academy of Dermatology strongly recommend the use of either 5-fluorouracil (5-FU) or imiquimod for the field treatment of actinic keratosis (AK). They also conditionally recommend the use of photodynamic therapy (P...

Tirbanibulin Ointment Clears Actinic Keratosis Lesions in Half of Recipients Within 2 Months
https://www.medscape.com/viewarticle/945635

Feb 11th, 2021 - NEW YORK (Reuters Health) - Just five treatments with an experimental ointment over five days were able to completely clear actinic keratosis lesions in half of all volunteers within two months, although one year after treatment the lesions had re...

Three in Four Adults 70 and Older Have at Least One Skin Disease
https://www.medscape.com/viewarticle/935774

Aug 17th, 2020 - (Reuters Health) - Skin diseases are highly prevalent among adults aged 70 years and older, with 75.7% of people in this age range reporting at least one skin disease requiring treatment or follow-up, a study in Finland suggests. Researchers exami...

Three in Four Adults 70 and Older Have at Least One Skin Disease
https://www.staging.medscape.com/viewarticle/935774

Aug 17th, 2020 - (Reuters Health) - Skin diseases are highly prevalent among adults aged 70 years and older, with 75.7% of people in this age range reporting at least one skin disease requiring treatment or follow-up, a study in Finland suggests. Researchers exami...

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Patient Education  4 results see all →