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About 4,402 results

ALLMedicine™ Langerhans Cell Histiocytosis Center

Research & Reviews  2,181 results

Extended treatment response to Imatinib in Rosai-Dorfman Disease.
https://doi.org/10.1111/ejh.13605
European Journal of Haematology; Singh A, Simons Y et. al.

Feb 23rd, 2021 - Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis, which can be classified as either localized to the lymph nodes or with extra-nodal disease. It was first reported by Dr. Dorfman in 1969 in a landmark paper describing sinus ...

Pregnant patient with extranodal CNS Rosai-Dorfman disease with new-onset seizures: the...
https://doi.org/10.1136/bcr-2020-239427
BMJ Case Reports; Swor K, Zutshi D et. al.

Feb 19th, 2021 - A 31-year-old woman at 30 weeks gestation presented to the emergency department following multiple seizures. Her history was significant for extranodal Rosai-Dorfman Disease (RDD) with central nervous system (CNS) lesions. RDD, a rare form of non-...

Histiocytosis and Neoplasms of Macrophage-Dendritic Cell Lineages: Multimodality Imagin...
https://doi.org/10.1148/rg.2021200096
Radiographics : a Review Publication of the Radiological ... Huynh KN, Nguyen BD

Feb 19th, 2021 - Histiocytosis is a rare inflammatory process characterized by pathologic infiltration and accumulation of cells derived from the monocytic lineage in normal tissue. It encompasses more than 100 different subtypes of disorders that were recently cl...

Unisystem Langerhans cell histiocytosis in maxillofacial region in pediatrics: comprehe...
https://doi.org/10.1007/s10006-021-00949-9
Oral and Maxillofacial Surgery; Chugh A, Kaur A et. al.

Feb 16th, 2021 - The study aimed to identify, enlist, and analyze cases of unisystem LCH in the maxillofacial pediatric population to understand the clinical presentation and encourage the consideration of this rare disease in the differential diagnosis. Langerhan...

Histiocytic Diseases of Neonates: Langerhans Cell Histiocytosis, Rosai-Dorfman Disease,...
https://doi.org/10.1016/j.clp.2020.11.008
Clinics in Perinatology; McClain KL

Feb 15th, 2021 - Langerhans cell histiocytosis, Rosai-Dorfman disease, and juvenile xanthogranuloma may present at birth or any time afterward. Some patients have minimal skin or lymph node involvement, but others present with life-threatening pulmonary, hepatic, ...

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Guidelines  3 results

The Mayo Clinic Histiocytosis Working Group Consensus Statement for the Diagnosis and E...
https://doi.org/10.1016/j.mayocp.2019.02.023
Mayo Clinic Proceedings; Goyal G, Young JR et. al.

Sep 1st, 2019 - Histiocytic neoplasms, a rare and heterogeneous group of disorders, primarily include Erdheim-Chester disease, Langerhans cell histiocytosis, and Rosai-Dorfman disease. Due to their diverse clinical manifestations, the greatest challenge posed by ...

Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work-up, and tr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557042
Pediatric Blood & Cancer; Haupt R, Minkov M et. al.

Oct 30th, 2012 - These guidelines for the management of patients up to 18 years with Langerhans cell histiocytosis (LCH) have been set up by a group of experts involved in the Euro Histio Net project who participated in national or international studies and in pee...

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Clinicaltrials.gov  2,191 results

Extended treatment response to Imatinib in Rosai-Dorfman Disease.
https://doi.org/10.1111/ejh.13605
European Journal of Haematology; Singh A, Simons Y et. al.

Feb 23rd, 2021 - Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis, which can be classified as either localized to the lymph nodes or with extra-nodal disease. It was first reported by Dr. Dorfman in 1969 in a landmark paper describing sinus ...

Pregnant patient with extranodal CNS Rosai-Dorfman disease with new-onset seizures: the...
https://doi.org/10.1136/bcr-2020-239427
BMJ Case Reports; Swor K, Zutshi D et. al.

Feb 19th, 2021 - A 31-year-old woman at 30 weeks gestation presented to the emergency department following multiple seizures. Her history was significant for extranodal Rosai-Dorfman Disease (RDD) with central nervous system (CNS) lesions. RDD, a rare form of non-...

Histiocytosis and Neoplasms of Macrophage-Dendritic Cell Lineages: Multimodality Imagin...
https://doi.org/10.1148/rg.2021200096
Radiographics : a Review Publication of the Radiological ... Huynh KN, Nguyen BD

Feb 19th, 2021 - Histiocytosis is a rare inflammatory process characterized by pathologic infiltration and accumulation of cells derived from the monocytic lineage in normal tissue. It encompasses more than 100 different subtypes of disorders that were recently cl...

Unisystem Langerhans cell histiocytosis in maxillofacial region in pediatrics: comprehe...
https://doi.org/10.1007/s10006-021-00949-9
Oral and Maxillofacial Surgery; Chugh A, Kaur A et. al.

Feb 16th, 2021 - The study aimed to identify, enlist, and analyze cases of unisystem LCH in the maxillofacial pediatric population to understand the clinical presentation and encourage the consideration of this rare disease in the differential diagnosis. Langerhan...

Histiocytic Diseases of Neonates: Langerhans Cell Histiocytosis, Rosai-Dorfman Disease,...
https://doi.org/10.1016/j.clp.2020.11.008
Clinics in Perinatology; McClain KL

Feb 15th, 2021 - Langerhans cell histiocytosis, Rosai-Dorfman disease, and juvenile xanthogranuloma may present at birth or any time afterward. Some patients have minimal skin or lymph node involvement, but others present with life-threatening pulmonary, hepatic, ...

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News  27 results

A 6-Year-Old Boy With Fever and Bone Swelling: Osmosis USMLE Study Question
https://www.staging.medscape.com/viewarticle/899198_2

Mar 5th, 2020 - Langerhans cell histiocytosis (LCH) is a neoproliferative disorder of Langerhans cells, the dendritic cells of the skin the mucosa. It often involves osteolytic bone lesions and invasion of multiple organs. There are tennis racket-shaped inclusion...

Hemorrhagic Crusted Papule on the Arm
https://www.mdedge.com/dermatology/article/178553/pediatrics/hemorrhagic-crusted-papule-arm
Somya Abubucker, MD, Jonathan Cuda, MD et. al.

Oct 31st, 2018 - The Diagnosis: Self-healing Langerhans Cell Histiocytosis Histopathologic examination showed an infiltrate of mononuclear cells with indented nuclei admixed with a variable dermal inflammatory infiltrate. Immunohistochemistry demonstrated cells th.

Vemurafenib granted sNDA, priority review for Erdheim-Chester disease
https://www.mdedge.com/hematology-oncology/article/144120/myelodysplastic-syndrome/vemurafenib-granted-snda-priority-review
Mary Jo M. Dales

Aug 7th, 2017 - Vemurafenib (Zelboraf) has been granted a supplemental new drug application and priority review by the Food and Drug Administration for the treatment of Erdheim-Chester disease with BRAF V600 mutation, according to a press release issued by Genent.

Purpuric Lesions of the Scalp, Axillae, and Groin of an Infant
https://www.mdedge.com/dermatology/article/139848/pediatrics/purpuric-lesions-scalp-axillae-and-groin-infant
Michele Khurana, MD, Jonathan S. Leventhal, MD et. al.

Jun 6th, 2017 - The Diagnosis: Langerhans Cell Histiocytosis Langerhans cell histiocytosis (LCH) is a clonal proliferative disorder of Langerhans cells that can affect any organ, most commonly the skin and bones. It typically develops in children aged 1 to 3 year.

Pediatric Dermatology Consult - April 2017
https://www.mdedge.com/familymedicine/article/136266/pediatric-dermatology-consult-april-2017
Pediatric News;

Apr 21st, 2017 - BY JEREMY UDKOFF AND CATALINA MATIZ, MD Juvenile xanthogranuloma (JXG), a non–Langerhans cell histiocytosis, is a common pediatric tumor that most commonly presents either at birth, in infants, or in young children – with the majority of cases occ.

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