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About 118 results

ALLMedicine™ Cylindroma Center

Research & Reviews  46 results

Surgical Treatment of Brooke-Spiegler Syndrome.
https://doi.org/10.1097/SCS.0000000000007144
The Journal of Craniofacial Surgery; Engels PE, Fritsche E et. al.

Nov 13th, 2020 - Brooke-Spiegler Syndrome (BSS) is a very rare autosomal dominant hereditary disease which arises from heterozygous mutations in the CYLD gene. Patients with BSS are predisposed to multiple skin appendage tumors such as cylindromas, which are benig...

Metaplastic spiradenocarcinoma: Report of two cases with sarcomatous differentiation.
https://doi.org/10.1111/cup.13897
Journal of Cutaneous Pathology; Held L, Ruetten A et. al.

Oct 15th, 2020 - Spiradenocarcinoma (SC) is a very rare malignant skin adnexal tumor with sweat gland differentiation that develops from a pre-existing spiradenoma, cylindroma, or hybrid tumor called spiradenocylindroma, or arises de novo. We present two exception...

Trichoepithelioma
https://emedicine.medscape.com/article/1060049-overview

Oct 9th, 2020 - Background Trichoepithelioma is a benign adnexal neoplasm. Cases associated with Brooke-Spiegler syndrome are caused by mutations of the cylindromatosis oncogene (CYLD), which maps to 16q12-q13. [1, 2, 3] A 2006 study has suggested that abnormalit...

Trichoepithelioma
https://emedicine.medscape.com/article/1060049-print

Oct 9th, 2020 - Background Trichoepithelioma is a benign adnexal neoplasm. Cases associated with Brooke-Spiegler syndrome are caused by mutations of the cylindromatosis oncogene (CYLD), which maps to 16q12-q13.[1, 2, 3] A 2006 study has suggested that abnormaliti...

CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcin...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817524
Modern Pathology : an Official Journal of the United Stat... Williams EA, Montesion M et. al.

Sep 7th, 2020 - Mutations in the tumor suppressor CYLD, known to be causative of cylindromas, were recently described in a subset of high-risk (hr) HPV-positive head and neck squamous cell carcinomas (HNSCC). Pathologic and genetic characterization of these CYLD-...

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News  1 results

Pearls for Excision and Management of Cylindromas
https://www.mdedge.com/internalmedicine/article/19916/dermatology/pearls-excision-and-management-cylindromas
Damian McNamara

Jan 11th, 2011 - ORLANDO – Surgical excision is the preferred approach for treating a patient who presents with a cylindroma or with the more extensive familial cylindromatosis, Dr. Leonard Slazinski said.

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