ALLMedicine™ Dermatofibrosarcoma Protuberans Center

May 14th, 2022 - COL1A1-PDGFB gene fusion uterine sarcoma is a recently described entity which shows some overlapping features with dermatofibrosarcoma protuberans. To date, only 4 cases have been reported in the literature. Due to its rarity, succinct clinicopath...

May 6th, 2022 - Immunohistochemical staining can be of great utility in differentiating various cutaneous spindle cell neoplasms, particularly when the histomorphologic appearance of the lesions is inconclusive. Nuclear staining for ETS-related gene (ERG), a high...

May 3rd, 2022 - We present an 81-year-old man who presented for evaluation of an indurated plaque with an exophytic, pearly, skin-red-brown colored nodule with central ulceration on his chest that evolved over the course of several months and was initially suspec...

Apr 23rd, 2022 - Dermatofibrosarcoma protuberans is a rare soft tissue sarcoma with a high recurrence rate. Herein, we present 68Ga-FAPI and 18F-FDG PET/CT findings of dermatofibrosarcoma protuberans in a 45-year-old man. Dermatofibrosarcoma protuberans only shows...

Apr 21st, 2022 - Dermatofibrosarcoma protuberans (DFSP) is a rare and marginal cutaneous sarcoma of intermediate-grade malignancy, for which the genomic landscape remains unclear. Understanding the landscape of DFSP will help to further classify the genomic pathwa...

Mar 7th, 2012 - Dermatofibrosarcoma protuberans.|2012|Miller SJ,Alam M,Andersen JS,Berg D,Bichakjian CK,|diagnosis,therapy,

Jan 20th, 2016 - OBJECTIVES: Primary Determine the response rate (complete response and partial response) in patients with metastatic, locally advanced, or locally recurrent non-gastrointestinal stromal tumor sarcomas treated with sunitinib malate. Secondary Deter...

Jan 10th, 2022 - The Diagnosis: Dermatofibrosarcoma Protuberans Histopathologic examination showed a dermal tumor composed of spindle cells in a storiform arrangement (Figure 1). Immunohistochemistry demonstrated positive CD34 staining of the tumoral cells (Figure.

Oct 6th, 2021 - Ibrahim S. Alshaygy, MD, MSC, a clinical fellow in Orthopedic Oncology at Mount Sinai Hospital, discusses research suggesting a smaller surgical resection margin for dermatofibrosarcoma protuberans (DFSP). DFSP is an uncommon continuous tumor wit...

Oct 5th, 2021 - Racial and ethnic disparities persist in the use of Mohs surgery to treat dermatofibrosarcoma protuberans, according to the results of a retrospective cohort study of more than 2,000 patients. Current guidelines recommend Mohs micrographic surgery...

May 25th, 2021 - Dysregulated platelet-derived growth factor receptor (PDGFR) signaling is implicated in a number of cancer types and is among the targets of many FDA-approved multikinase inhibitors.1,2 Despite the success of these drugs in a range of malignancies...

Dec 20th, 2020 - William D. Tap, MD Abstract The characterization of molecular abnormalities implicated in the tumorigenesis of sarcomas is being increasingly applied to the classification, prognostication and, in particular situations, management of these ...