ALLMedicine™ Lentigo Maligna Melanoma Center

May 2nd, 2022 - The rates of melanoma continue to rise, with recent estimates have shown that 18% to 22% of new melanoma cases occur within the head and neck in the United States each year. The mainstay of treatment of nonmetastatic primary melanomas of the head ...

Mar 30th, 2022 - CONCORD-3 highlighted wide disparities in population-based 5-year net survival during 2000-2014. Clinical evidence suggests marked international differences in the proportion of lethal acral and nodular subtypes. We aim to assess whether the diffe...

Mar 23rd, 2022 - Practice Essentials A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin (see the image below), can arise in ...

Mar 23rd, 2022 - Practice Essentials A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin (see the image below), can arise in ...

Jan 16th, 2022 - In their article in the Journal of Investigative Dermatology, Conway et al. (2021) show the significance of the CpG island methylator phenotype (CIMP) subclass in early-stage invasive primary melanomas, particularly in the lentigo maligna melanoma...

Oct 23rd, 2019 - Lentigo maligna (LM) is a subtype of melanoma in situ that usually occurs in sun-damaged skin and is characterised by an atypical proliferation of melanocytes within the basal epidermis. If left untreated, LM can develop into invasive melanoma, te...

Dec 5th, 2020 - Metastatic melanoma has limited treatment options, but advances in the understanding of the oncogenic mutations that drive this cancer and how the immune system can be better modulated to fight melanoma provide a new generation of active approache...

Sep 4th, 2020 - The Melanoma Institute Australia (MIA) nomogram was found to accurately estimate the risk of sentinel node metastasis positivity in patients with melanoma and its use could help to reduce the rate of unnecessary invasive biopsies without sacrifici...

Mar 7th, 2019 - The FP suspected that this was a skin cancer with ulceration and pigmentation. The differential diagnosis included pigmented basal cell carcinoma, melanoma, and squamous cell carcinoma.

Feb 28th, 2019 - The FP was concerned that this could be melanoma. He used his dermatoscope and saw suspicious patterns that included polygonal lines and circle-within-circle patterns.

Sep 6th, 2018 - The FP suspected melanoma and recommended immediate biopsy. The patient consented, and the physician performed a broad shave biopsy that included most of the pigmented lesion.