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About 165 results

ALLMedicine™ Atopic Keratoconjunctivitis Center

Research & Reviews  63 results

Vernal keratoconjunctivitis: An update.
https://doi.org/10.1177/11206721211022153
European Journal of Ophthalmology; Ghiglioni DG, Zicari AM et. al.

Jun 2nd, 2021 - Vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) are potentially severe and complex disease in its management among the various allergic eye diseases. In this regard, studies clarified the etiopathogenetic mechanisms. The wo...

The FADS mouse: A novel mouse model of atopic keratoconjunctivitis.
https://doi.org/10.1016/j.jaci.2021.05.017
The Journal of Allergy and Clinical Immunology; Nunomura S, Kitajima I et. al.

May 29th, 2021 - Atopic keratoconjunctivitis (AKC) is a chronic allergic conjunctival disease. However, a mouse model of AKC to investigate the underlying mechanism and to estimate the efficacy of the therapeutic agents has not been established. We recently genera...

Tear N-glycomics in vernal and atopic keratoconjunctivitis.
https://doi.org/10.1111/all.14775
Allergy Messina A, Palmigiano A et. al.

Feb 15th, 2021 - Tear fluid N-Glycome from patients affected with vernal (VKC) and atopic keratoconjunctivitis (AKC) was investigated to identify specific changes in tears and to recognize possible glyco-biomarkers. The analysis of the N-glycans was performed usin...

IL-1α antibody inhibits dose-dependent exacerbation of eosinophilic inflammation by cru...
https://doi.org/10.1080/02713683.2021.1874022
Current Eye Research; Shiraki Y, Shoji J et. al.

Jan 12th, 2021 - To investigate whether crude house-dust-mite antigen exacerbates eosinophilic inflammation in the conjunctival tissues of an atopic keratoconjunctivitis mouse model in a dose-dependent manner. An atopic keratoconjunctivitis mouse model was establi...

Systemic interventions for severe atopic and vernal keratoconjunctivitis in children an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8078190
The Cochrane Database of Systematic Reviews; Kim SE, Nowak V et. al.

Oct 22nd, 2020 - Atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC) are severe and potentially sight-threatening allergic eye diseases characterised by chronic inflammation of the ocular surface. Both topical and systemic treatments are used. ...

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Clinicaltrials.gov  3 results

A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and Perennial Allergic Conjunctivitis
https://clinicaltrials.gov/ct2/show/NCT03379311

Aug 29th, 2019 - This is a Phase 1b, open-label, study to assess the effects of AK002, given as monthly intravenous infusion for 6 doses at up to 3 mg/kg.

Dermatologic Tacrolimus Ointment on Eyelids in the Treatment of Refractory Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis
https://clinicaltrials.gov/ct2/show/NCT03557203

Jun 14th, 2018 - Treatment of vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) is a challenge for the ophthalmologist and patients because of its wide variation in presentation and recurrence in nature. Patients has to be dependent on long t...

Efficacy and Safety Study of Cyclosporine 0.010% to Treat Atopic Keratoconjunctivitis
https://clinicaltrials.gov/ct2/show/NCT00884585

Nov 5th, 2012 - This study evaluates the efficacy and safety of Cyclosporine 0.010% eye drops in the treatment of Atopic Keratoconjunctivitis (chronic and severe inflammation of the eye). The study consists of a double-masked phase, and open-labeled phase, and an...

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