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About 745 results

ALLMedicine™ Fungal Keratitis Center

Research & Reviews  288 results

Dexamethasone (0.4mg) Ophthalmic Insert.
https://clinicaltrials.gov/ct2/show/NCT05372315

May 12th, 2022 - This is a randomized, controlled study to evaluate the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iSte...

Gellan gum-based in situ gelling ophthalmic nanosuspension of Posaconazole.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9089292
Drug Delivery and Translational Research; Khare P, Chogale MM et. al.

May 11th, 2022 - The formulation and delivery of highly hydrophobic drugs in an optimized dosage form is challenging to formulation scientists. Posaconazole has shown promising action in case studies against fungal keratitis. Biological macromolecules like gellan ...

Inhibition of Galectin-3 Impairs Antifungal Immune Response in Fungal Keratitis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9013289
Disease Markers; Xiao Y, Yang J et. al.

Apr 20th, 2022 - Galectin-3 is one of the galectin family members which are master regulators of immune homeostasis, especially in infectious diseases. However, its mechanism of immune regulation in fungal keratitis has not been thoroughly studied. Our study is ai...

Eugenol protects against Aspergillus fumigatus keratitis by inhibiting inflammatory res...
https://doi.org/10.1016/j.ejphar.2022.174955
European Journal of Pharmacology; Yu B, Li C et. al.

Apr 19th, 2022 - Fungal keratitis is a corneal infection, which severely impairs vision. The fungal pathogen provokes host immune response, but the excessive inflammatory response causes significant collateral damage to the cornea. Eugenol, the main component of c...

Case Report: Novel Patient Training Technique for the Application and Removal of Sclera...
https://doi.org/10.1097/OPX.0000000000001905
Optometry and Vision Science : Official Publication of Th... Kwok A, Derby S et. al.

Apr 13th, 2022 - This report shares a technique that can be utilized to assist training patients to properly and safely apply and remove prosthetic replacement of the ocular surface ecosystem devices (PD) or scleral lenses in order to reduce patient training nervo...

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Drugs  2 results see all →

Clinicaltrials.gov  2 results

Dexamethasone (0.4mg) Ophthalmic Insert.
https://clinicaltrials.gov/ct2/show/NCT05372315

May 12th, 2022 - This is a randomized, controlled study to evaluate the safety and effectiveness of treatment with an intracanalicular dexamethasone (0.4mg) insert in the operating room following cataract surgery/intraocular lens implant (IOL) with or without iSte...

Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers
https://clinicaltrials.gov/ct2/show/NCT02731638

Oct 1st, 2019 - The proposed study is a randomized controlled trial to determine whether intrastromal voriconazole improves outcomes in fungal keratitis. Patients presenting to the Aravind Eye Hospitals in Pondicherry, India for treatment of fungal keratitis will...

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News  6 results

Predictors of Fungal Keratitis-related Corneal Perforation Identified
https://www.medscape.com/viewarticle/884660

Aug 25th, 2017 - NEW YORK (Reuters Health) – Baseline presence of hypopyon and infiltrate depth and size are significant predictors of corneal perforation and/or need for therapeutic penetrating keratoplasty (TPK) in patients with severe fungal keratitis, research...

The Best Tx for Fungal Keratitis: Ophthalmology Times
https://www.medpagetoday.com/ophthalmology/generalophthalmology/66295

Jun 27th, 2017 - One expert discusses the importance of improving diagnosis and treatment options for nonresponsive bacterial keratitis. A new oral formulation of itraconazole decreased tumor size in patients with basal cell carcinoma nevus syndrome, according to ...

Outbreak of Eye Fungus Prompts FDA Warning
https://www.medpagetoday.com/surgery/ophthalmology/3072

Apr 11th, 2006 - Action Points Explain to patients who ask that good hygiene can significantly reduce the risk of infection among users of soft contact lenses. Explain to patients who ask that wearing lenses overnight increases the risk of infection. ROCKVILLE, Md...

Cluster Of Fungal Eye Infections Worries Experts
https://www.medpagetoday.com/infectiousdisease/publichealth/3032

Apr 7th, 2006 - Action Points Advise patients who ask that eye experts and the CDC are watching some clusters of keratitis caused by Fusarium, a fungus found in soil and on plants. When treating an eye infection that does not respond quickly to antibiotics, consi...

Fusarium Keratitis Cases Spur Call for Vigilance
https://www.mdedge.com/pediatrics/article/39407/infectious-diseases/fusarium-keratitis-cases-spur-call-vigilance
Mary Ann Moon

The recent outbreak of fusarium keratitis that spread to 33 states carried “a high degree of morbidity,” with corneal transplantation required or planned for 55 of the 164 affected patients identified, reported Dr. Douglas C.

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