About 164 results
Ocular Complications of Atopic Dermatitis

Sep 4th, 2019 - Keratoconus Keratoconus is a noninflammatory ocular disorder characterized by progressive thinning and conelike protrusion of the cornea. The corneal topographic changes result in high irregular astigmatism and reduced visual acuity, which can manifest as image blurring or distortion (Figure 2).

High-Dose Steroids: Worth the Risk in Bacterial Keratitis?

Apr 8th, 2019 - As eye care physicians, we often encounter corneal infections in our patients. Fortunately, most of these infections are mild, respond quickly to standard topical antibiotic treatment alone, and resolve without significant corneal scarring or decreased vision. In those infections that are more severe, however, the risk of visually significant scarring is substantial. The corneal damage that lea...

Corneal Crosslinking: Is Using an Epithelium-On Technique Effective?

Feb 13th, 2019 - Corneal collagen crosslinking (CXL) has been available in Europe for nearly 15 years, beginning with its discovery in 1997 by the German ophthalmologist Theo Seiler and the subsequent publishing of its first clinical results in 2003 by Wollensak and colleagues.[1] The goal of CXL is to halt the progression of keratoconus, and in general, it does and often flattens keratometry by 1-2 diopters. T...

Tegaderm eliminates corneal abrasions in robotic gynecologic surgery
M. Alexander Otto

Nov 18th, 2018 - LAS VEGAS – There hasn’t been a single corneal abrasion in 860 cases of gynecologic robotic surgery at the University of Texas, Austin, since surgeons and anesthesiologists there started sealing women’s eyes shut with a thick layer of ointment and Tegaderm, instead of the usual small squeeze of ointment and tape, according to Michael T. Breen, MD, a gynecologic surgeon at the university.

Is Crosslinked Corneal Donor Tissue Beneficial in PK?

Jan 24th, 2018 - Use of Donors Predisposed by Corneal Collagen Cross-linking in Penetrating Keratoplasty for Treating Patients With Keratoconus Huang T, Ye R, Ouyang C, Hou C, Hu Y, Wu Q Am J Ophthalmol. 2017;184:115-120 Background Eyes with keratoconus undergoing corneal transplantation have among the highest success rates as far as graft clarity and longevity of all eyes undergoing keratoplasty. Many, if not ...

Which Type of Keratoplasty Is Best for Corneal Endothelial Dysfunction?

Oct 15th, 2017 - NEW YORK (Reuters Health) - Descemet membrane endothelial keratoplasty (DMEK) offers advantages over the more widely used Descemet stripping endothelial keratoplasty (DSEK) for the surgical treatment of corneal endothelial dysfunction, according to an Ophthalmic Technology Assessment from the American Academy of Ophthalmology. "DMEK should be choice of procedure for uncomplicated endothelial fa...

Predictors of Fungal Keratitis-related Corneal Perforation Identified

Aug 24th, 2017 - NEW YORK (Reuters Health) – Baseline presence of hypopyon and infiltrate depth and size are significant predictors of corneal perforation and/or need for therapeutic penetrating keratoplasty (TPK) in patients with severe fungal keratitis, researchers say. To determine which patients might be at higher risk of poor outcomes from infectious keratitis, Dr. Jennifer Rose-Nussbaumer of the Universit...

Collagen Corneal Crosslinking: What Your Patients Can Expect

Aug 20th, 2017 - Hi. I'm Dr Christopher Rapuano, chief of the Cornea Service at Wills Eye Hospital in Philadelphia, where I'm coming to you from the Alumni Society Newsroom. I'd like to give a brief update on collagen corneal crosslinking (CXL) and its current use in the United States. Keratoconus is a fairly common condition in which the cornea (the clear covering of the eye) gets abnormally thin and pointy, t...

Eye disease affects 1 in 5 adults with severe atopic dermatitis
Jennie Smith

Aug 11th, 2017 - Results of a large cohort study in Denmark found that adults with atopic dermatitis (AD) were significantly more likely to be affected by certain ocular conditions, compared with those who did not have AD. “Keratitis, conjunctivitis, and keratoconus as well as cataracts in patients younger than 50 years occurred more frequently in patients with AD and in a disease severity–dependent manner,” co.

Corneal Crosslinking: Taking a Closer Look at the Data That Convinced the FDA

Jul 18th, 2017 - United States Multicenter Clinical Trial of Corneal Collagen Crosslinking for Keratoconus Treatment Hersh PS, Stulting RD, Muller D, Durrie DS, Rajpal RK; United States Crosslinking Study Group Ophthalmology. 2017 May 7. [Epub ahead of print] Study Summary Corneal collagen crosslinking (CXL), a procedure to strengthen the cornea originally devised to treat patients with keratoconus, is now also...

The Best Tx for Fungal Keratitis: Ophthalmology Times

Jun 27th, 2017 - One expert discusses the importance of improving diagnosis and treatment options for nonresponsive bacterial keratitis. A new oral formulation of itraconazole decreased tumor size in patients with basal cell carcinoma nevus syndrome, according to a recent analysis of a trial data. A phase III study found that the intracanalicular insert dexamethasone is a safe and effective treatment for ocular...

CHMP Backs Cenegermin (Oxervate) for Neurotrophic Keratitis

May 18th, 2017 - The European Medicines Agency's (EMA's) Committee for Medicinal Products for Human Use (CHMP) recommended granting marketing authorization for cenegermin (Oxervate, Dompé farmaceutici S.p.A.) for the treatment of adults with moderate (persistent epithelial defect) or severe (corneal ulcer) neurotrophic keratitis on May 18, 2017. Cenegermin was designated as an orphan medicinal product on Decemb...

Eyeing Disease Spread in Donor Corneas: Ophthalmology Times

May 9th, 2017 - Surgeons, eye banks, and other organizations must remain vigilant about monitoring donor corneal tissue to minimize the risk of disease transmission. Although complications from corneal crosslinking to treat progressive keratoconus are rare, it's important to know when the cornea is most vulnerable. One expert assesses the risks. After cataract surgery, patients often fail to stick to their eye...

Keratoconus: More Common Than You Think

Apr 4th, 2017 - Age-Specific Incidence and Prevalence of Keratoconus: A Nationwide Registration Study Godefrooij DA, de Wit GA, Uiterwaal CS, Imhof SM, Wisse RP Am J Ophthalmol. 2017;175:169-172 Study Summary The commonly quoted number for the prevalence of keratoconus is 1:2000, which is pretty rare, although it varies by region of the world. Using mandatory health insurance data on 4.4 million patients from ...

Long-term Outcomes of Endothelial Keratoplasty Win Over Penetrating Keratoplasty

Jan 16th, 2017 - Changing Practice Patterns and Long-term Outcomes of Endothelial Versus Penetrating Keratoplasty: A Prospective Dutch Registry Study Dickman MM, Peeters JM, van den Biggelaar FJ, et al Am J Ophthalmol. 2016;170:133-142 Study Summary The authors looked at the changing practice patterns in corneal transplantation and compared the long-term outcomes of Descemet stripping endothelial keratoplasty (...

Treating Bacterial Keratitis in Developing Countries

Jan 11th, 2017 - Prospective, Randomized Clinical Trial of Povidone-Iodine 1.25% Solution Versus Topical Antibiotics for Treatment of Bacterial Keratitis Isenberg SJ, Apt L, Valenton M, et al Am J Ophthalmol. 2016 Oct 27. [Epub ahead of print] Corneal scarring is the most common cause of preventable blindness in children in the developing world.[1,2] Malnutrition, particularly vitamin A deficiency, predisposes ...

Accelerated Crosslinking Effective for Keratoconus

Jan 11th, 2017 - Accelerated transepithelial corneal crosslinking safely and effectively treats progressive keratoconus, researchers say. Using increased illumination intensity, the technique achieves crosslinking in a few minutes rather than the hour required for the conventional procedure, write Wei Aixinjueluo, MD, and colleagues from the Department of Ophthalmology at the University of Tokyo in Japan. "We o...

Alternative to Corneal Transplant for Keratoconus Promising

Oct 24th, 2016 - CHICAGO — For people with keratoconus, the minimally invasive transplantation of just the second layer of the cornea — the Bowman layer — can help delay or prevent full corneal transplantation or other high-risk procedures, new results from a long-term study show. The 5-year findings — which build on 3-year data — were presented here at the American Academy of Ophthalmology 2016 Annual Meeting ...

A Cloudy and Painful Eye

Sep 7th, 2016 - Clinical Presentation A 30-year-old black man presented to the emergency service with a chief complaint of sudden-onset pain in the left eye that has lasted for the past 3 days. He denied trauma and discharge but stated that he was very light-sensitive. His ocular history was remarkable for a diagnosis of keratoconus in both eyes since 2007. The patient was lost to follow-up after his last eye ...

Traumatic Injury in One Eye Followed by a Hyperopic Shift in the Other: Are They Related?

Sep 5th, 2016 - Clinical Presentation A 30-year-old white woman sustained an injury to her right eye while working at a vineyard. When she bent over to remove a cluster of grapes, she was poked in the eye with a fastening wire. She was evaluated at the local emergency room, where she was treated with topical antibiotics for a corneal abrasion, and was referred to an ophthalmologist. However, that evening, the ...