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About 5,140 results

ALLMedicine™ Stevens-Johnson Syndrome Center

Research & Reviews  1,002 results

Orbital Compartment Syndrome in Severe Burns: Predictive Factors, Timing, and Complicat...
https://doi.org/10.1097/IOP.0000000000002313
Ophthalmic Plastic and Reconstructive Surgery; Echalier EL, Larochelle RD et. al.

Jan 27th, 2023 - Severe burn patients require high-volume fluid resuscitation, which increases risk for orbital compartment syndrome (OCS). We aimed to understand surgeons' practice patterns and to examine risk factors for OCS, timing of lateral canthotomy and can...

Corneal Graft Rejection
https://emedicine.medscape.com/article/1193505-overview

Jan 23rd, 2023 - Background Although described for more than 100 years, corneal transplantation has become increasingly common since the 1960s. In 2021, approximately 80,000 corneal transplantations were performed in the United States. [1] Corneal graft rejection ...

Distichiasis
https://emedicine.medscape.com/article/1212908-print

Jan 23rd, 2023 - Background Distichiasis is a rare disorder defined as the abnormal growth of lashes from the orifices of the meibomian glands on the posterior lamella of the tarsal plate.[1] This picture demonstrates distichiasis of the lower lid. From Principles...

Corneal Graft Rejection
https://emedicine.medscape.com/article/1193505-print

Jan 23rd, 2023 - Background Although described for more than 100 years, corneal transplantation has become increasingly common since the 1960s. In 2021, approximately 80,000 corneal transplantations were performed in the United States.[1] Corneal graft rejection i...

Corneal Graft Rejection
http://emedicine.medscape.com/article/1193505-overview

Jan 23rd, 2023 - Background Although described for more than 100 years, corneal transplantation has become increasingly common since the 1960s. In 2021, approximately 80,000 corneal transplantations were performed in the United States. [1] Corneal graft rejection ...

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Guidelines  5 results

Society of Dermatology Hospitalists supportive care guidelines for the management of St...
https://doi.org/10.1016/j.jaad.2020.02.066
Journal of the American Academy of Dermatology; Seminario-Vidal L, Kroshinsky D et. al.

Mar 11th, 2020 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by...

Outpatient management and follow-up recommendations for adverse drug reactions: guideli...
https://www.ncbi.nlm.nih.gov/pubmed/31233575
Cutis Khanna R, Vaudreuil A et. al.

Jun 25th, 2019 - Acute generalized exanthematous pustulosis (AGEP), drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are types of adverse drug reactions (ADRs), each with their ...

British Association of Dermatologists' guidelines for the management of Stevens-Johnson...
https://doi.org/10.1111/bjd.17841
The British Journal of Dermatology; McPherson T, Exton LS et. al.

Mar 5th, 2019 - British Association of Dermatologists' guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018.|2019|McPherson T,Exton LS,Biswas S,Creamer D,Dziewulski P,|methods,standards,standards,...

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847474
Clinical Pharmacology and Therapeutics; Phillips EJ, Sukasem C et. al.

Feb 3rd, 2018 - The variant allele HLA-B*15:02 is strongly associated with greater risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine. The variant allele HLA-A*31:01 is associated wi...

Clinical Pharmacogenetics Implementation Consortium guidelines for HLA-B genotype and c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748365
Clinical Pharmacology and Therapeutics; Leckband SG, Kelsoe JR et. al.

May 23rd, 2013 - Human leukocyte antigen B (HLA-B) is a gene that encodes a cell surface protein involved in presenting antigens to the immune system. The variant allele HLA-B*15:02 is associated with an increased risk of Stevens-Johnson syndrome (SJS) and toxic e...

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Drugs  849 results see all →

Clinicaltrials.gov  26 results

NATIENS: Optimal Management and Mechanisms of SJS/TEN
https://clinicaltrials.gov/ct2/show/NCT02987257

Dec 30th, 2022 - Background and Scientific Rationale Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe, life-threatening immunologically mediated adverse drug reactions representing the same disease across a spectrum of severity that ...

The OBstetric Lidocaine Patch (OBLido) Trial
https://clinicaltrials.gov/ct2/show/NCT03810235

Nov 1st, 2022 - The purpose of this study is to determine whether transdermal lidocaine administered at the time of Cesarean delivery and for 12 hours postoperatively will reduce the total dose of opioids received. Our hypothesis is that a lidocaine patch will re...

Nutritional and Metabolic Management of Toxidermia Patients Requiring Intensive Care (TEN Metabolism)
https://clinicaltrials.gov/ct2/show/NCT05320653

Aug 5th, 2022 - There are yet no description of the metabolic characteristics of patients admitted for Toxic epidermal necrolysis (TEN) or Stevens-Johnson Syndrome (SJS) which are a rare condition, often assimilated to major burns in terms of metabolic requiremen...

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
https://clinicaltrials.gov/ct2/show/NCT03041883

Jul 7th, 2022 - The Boston type 1 keratoprosthesis (KPro) is an artificial cornea that restores the clarity of the visual axis. It is indicated in patients for whom conventional corneal transplantation offers a very low probability of success. Several innovations...

LYell SYndrome MEsenchymal Stromal Cells Treatment
https://clinicaltrials.gov/ct2/show/NCT04711200

May 3rd, 2022 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous adverse reactions (SCARs) to drugs. To date, no curative drug has demonstrated with a good level of evidence its ability to promote SJS and TEN healing a...

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News  160 results

Diffuse Papular Eruption With Erosions and Ulcerations
https://www.mdedge.com/dermatology/article/259651/dermatopathology/diffuse-papular-eruption-erosions-and-ulcerations
Lauren N. Gresham, MD, Brooks David Kimmis, MD et. al.

Nov 21st, 2022 - The Diagnosis: Immunotherapy-Related Lichenoid Drug Eruption Direct immunofluorescence was negative, and histopathology revealed a lichenoid interface dermatitis, minimal parakeratosis, and saw-toothed rete ridges (Figure 1). He was diagnosed with.

Which Regenerative Methods Are Used for Healing the Cornea?
https://www.medscape.com/viewarticle/983656

Nov 7th, 2022 - In ophthalmology, there are several approved, biotechnologically manufactured, regenerative medicine products that are used as eye drops or as transplants for corneal diseases. Gerd Geerling, MD, PhD, professor of ophthalmology at University Hospi...

Chlorophyll water can trigger pseudoporphyria, expert warns
https://www.mdedge.com/dermatology/article/257435/pediatrics/chlorophyll-water-can-trigger-pseudoporphyria-expert-warns
Doug Brunk

Aug 30th, 2022 - PORTLAND, ORE. – If a child presents with pseudoporphyria – a bullous photodermatosis with the clinical and histological features of porphyria cutanea tarda (PCT) but with normal porphyrins – chlorophyll water could be the culprit.

Chlorophyll Water Can Trigger Pseudoporphyria, Expert Warns
https://www.medscape.com/viewarticle/979969

Aug 30th, 2022 - PORTLAND, ORE. – If a child presents with pseudoporphyria – a bullous photodermatosis with the clinical and histological features of porphyria cutanea tarda (PCT) but with normal porphyrins – chlorophyll water could be the culprit. Commercially av...

ALL-HEART: No Benefit of Allopurinol in Ischemic Heart Disease
https://www.medscape.com/viewarticle/979859

Aug 28th, 2022 - Allopurinol, a drug commonly used to treat gout, provided no benefit in terms of reducing cardiovascular (CV) events in patients with ischemic heart disease, new randomized trial results show. Treatment of these patients without gout with 600 mg o...

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Patient Education  14 results see all →