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About 3,653 results

ALLMedicine™ Stevens-Johnson Syndrome Center

Research & Reviews  828 results

Genetic markers for methazolamide-induced Stevens-Johnson syndrome and toxic epidermal ...
https://doi.org/10.1111/jdv.18158
Journal of the European Academy of Dermatology and Venere... Huang PW, Chu CY

May 11th, 2022 - Genetic markers for methazolamide-induced Stevens-Johnson syndrome and toxic epidermal necrolysis.|2022|Huang PW,Chu CY,|

Photodistributed Toxic Epidermal Necrolysis: Case Report and Review of Current Literature.
https://doi.org/10.1001/jamadermatol.2022.1090
JAMA Dermatology; Gaghan LJ, Coates MM et. al.

May 5th, 2022 - Cases of photodistributed Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have been infrequently reported since the first documented case in 1989. This emerging clinical entity and its underlying mechanism have yet to be fully ...

Rare case of Stevens-Johnson syndrome with bronchiolitis obliterans as a chronic compli...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039386
BMJ Case Reports; Mitani K, Hida S et. al.

Apr 27th, 2022 - A young girl in her teens presented with fever, rashes and various mucocutaneous symptoms. Flat erythematous macules were seen mainly on the limbs, without blisters or skin detachments. The lips were swollen with crusts and haemorrhage. The oral c...

Antibody-Negative Paraneoplastic Autoimmune Multiorgan Syndrome (PAMS) in a Patient wit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9032549
Current Oncology (Toronto, Ont.); Gambichler T, Lee YP et. al.

Apr 22nd, 2022 - Paraneoplastic autoimmune multiorgan syndrome (PAMS) is a life-threatening autoimmune disease associated with malignancies. Here, we present a patient initially misdiagnosed with "chronic" Stevens-Johnson syndrome. Over a year later, the patient w...

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Guidelines  5 results

Society of Dermatology Hospitalists supportive care guidelines for the management of St...
https://doi.org/10.1016/j.jaad.2020.02.066
Journal of the American Academy of Dermatology; Seminario-Vidal L, Kroshinsky D et. al.

Mar 11th, 2020 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by...

Outpatient management and follow-up recommendations for adverse drug reactions: guideli...
https://www.ncbi.nlm.nih.gov/pubmed/31233575
Cutis Khanna R, Vaudreuil A et. al.

Jun 25th, 2019 - Acute generalized exanthematous pustulosis (AGEP), drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, and Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) are types of adverse drug reactions (ADRs), each with their ...

British Association of Dermatologists' guidelines for the management of Stevens-Johnson...
https://doi.org/10.1111/bjd.17841
The British Journal of Dermatology; McPherson T, Exton LS et. al.

Mar 5th, 2019 - British Association of Dermatologists' guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018.|2019|McPherson T,Exton LS,Biswas S,Creamer D,Dziewulski P,|methods,standards,standards,...

Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847474
Clinical Pharmacology and Therapeutics; Phillips EJ, Sukasem C et. al.

Feb 3rd, 2018 - The variant allele HLA-B*15:02 is strongly associated with greater risk of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients treated with carbamazepine or oxcarbazepine. The variant allele HLA-A*31:01 is associated wi...

Clinical Pharmacogenetics Implementation Consortium guidelines for HLA-B genotype and c...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748365
Clinical Pharmacology and Therapeutics; Leckband SG, Kelsoe JR et. al.

May 23rd, 2013 - Human leukocyte antigen B (HLA-B) is a gene that encodes a cell surface protein involved in presenting antigens to the immune system. The variant allele HLA-B*15:02 is associated with an increased risk of Stevens-Johnson syndrome (SJS) and toxic e...

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Drugs  520 results see all →

Clinicaltrials.gov  7 results

Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
https://clinicaltrials.gov/ct2/show/NCT03041883

Jul 30th, 2021 - The Boston type 1 keratoprosthesis (KPro) is an artificial cornea that restores the clarity of the visual axis. It is indicated in patients for whom conventional corneal transplantation offers a very low probability of success. Several innovations...

Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial
https://clinicaltrials.gov/ct2/show/NCT04396314

Mar 19th, 2021 - This protocol of research is addressed to assess the effectiveness of Basic Body Awareness Therapy (BBAT) as physiotherapist intervention adjunct treatment as usual with the aim to improve the symptoms of post-traumatic stress disorder (PTSD) in s...

An Exploratory Study of Genetic and Clinical Factors for Serious Skin Reactions Among Users of Eslicarbazepine Acetate
https://clinicaltrials.gov/ct2/show/NCT02520557

Jan 22nd, 2021 - This study is a genetic case-control study conducted in the United States. In case-control studies, cases with a condition of interest (in this case, individuals with SCAR [severe cutaneous adverse reactions] after initiating ESL); and controls, i...

Serum Interleukin -21 Level in Patients With Severe Adverse Cutaneous Drug Reaction.
https://clinicaltrials.gov/ct2/show/NCT03166241

May 25th, 2017 - Erythema multiforme is an acute immune mediated disorder It is a type IV hypersensitivity reaction leading to dermal vasculitis. Erythema multiforme major usually as a result of medications such as sulphonamides, non-steroidal anti-inflammatories ...

Topical Infliximab in Autoimmune Eyes With Keratoprosthesis
https://clinicaltrials.gov/ct2/show/NCT02126020

Apr 7th, 2017 - This is an unmasked, prospective, multicenter clinical trial of four patients that are candidates for a Boston Keratoprosthesis or have had prior KPro surgery and have a diagnosis of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis syndr...

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News  97 results

Age, Skin Cancer Risks for ICI-Induced Bullous Pemphigoid
https://www.medscape.com/viewarticle/972516

Apr 21st, 2022 - Bullous pemphigoid, an immune-mediated condition chacterized by large, fluid-filled blisters on the skin, is a rare but serious complication of cancer therapy with immune checkpoint inhibitors (ICIs) that may result in treatment interruption or ce...

Blistering Lesions in a Newborn
https://www.mdedge.com/dermatology/article/253884/pediatrics/blistering-lesions-newborn
Gabriella Alvarez, BS, Shivani Shah, DO, MPH et. al.

Apr 19th, 2022 - The Diagnosis: Epidermolysis Bullosa Our patient was found to have epidermolysis bullosa (EB), a rare genetic disease in which the superficial layers of the skin separate to form vesicles or bullae due to a mutation in the keratin 14 gene, KRT14.

Adverse Skin Effects of Cancer Immunotherapy Reviewed
https://www.medscape.com/viewarticle/970581

Mar 18th, 2022 - Immune checkpoint inhibitors (ICIs) have unquestionably revolutionized the care of patients with malignant melanoma, non-small cell lung cancer, and other types of cancer. But about 40% of patients with cancer treated with ICIs will experience imm...

Expert Highlights Management of Immune-Related Toxicities With NSCLC Treatment
https://www.onclive.com/view/expert-highlights-management-of-immunerelated-toxicities-with-nsclc-treatment

Oct 6th, 2021 - Mohamed K. Mohamed, MD Pembrolizumab (Keytruda) has emerged as a reliable frontline treatment option for patients with metastatic non—small cell lung cancer (NSCLC), but thoracic oncologists need to be aware of potentially severe immune-related a...

Severe Skin Reactions With Enfortumab Vedotin
https://www.medscape.com/viewarticle/958754

Sep 15th, 2021 - Use of enfortumab vedotin (Padcev), which was approved less than 2 years ago for the treatment of metastatic urothelial cancer, has been associated with cases of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), some of which we...

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Patient Education  4 results see all →