About 180 results
Seborrhea Herpeticum: Cutaneous Herpes Simplex Virus Infection Within Infantile Seborrheic Dermatitis
Laryn Steadman, MD, Katherine Hrynewycz, MD et. al.

Nov 5th, 2019 - Classically, eczema herpeticum is associated with atopic dermatitis (AD), but it also has been previously reported in the setting of pemphigus vulgaris, Darier disease, ichthyosis vulgaris, burns, psoriasis, and irritant contact dermatitis. 1,2 Descriptions of cutaneous herpes simplex virus (HSV) in the setting of seborrheic dermatitis are lacking.

How to distinguish Stevens-Johnson syndrome from its mimickers
Kari Oakes

Sep 10th, 2019 - NEW YORK – Inpatient dermatology consults can make all the difference when a serious dermatology complication is suspected, said Lucia Seminario-Vidal, MD, PhD, speaking at a hospital dermatology–focused session of the summer meeting of the American Academy of Dermatology. Even before histopathologic results are available, dermatologists can help take some of the panic out of the room when Stev.

Peeling skin with chills
MDedge Family Medicine;

Aug 8th, 2019 - The physician thought that this was most likely toxic epidermal necrolysis (TEN). He was in a small hospital without a burn unit, so he drew baseline labs and blood cultures, and started to give intravenous fluids to treat the dehydration.

Fast Five Quiz: Ocular Rosacea

Jun 3rd, 2019 - Ocular rosacea, a chronic condition characterized by redness, burning, and itching of the eyes, is a comorbidity commonly seen in patients with a history of facial rosacea. In a minority of patients, however, ocular rosacea may present prior to onset of cutaneous manifestations. The underlying pathophysiology of rosacea is thought to be associated with abnormalities in the body's immune respons...

Asboe-Hansen Sign in Toxic Epidermal Necrolysis
Jessica R. Dowling, BA, Kathryn L. Anderson, MD et. al.

Apr 11th, 2019 - To the Editor: A 25-year-old woman with no notable medical history was admitted to the hospital for suspected Stevens-Johnson syndrome (SJS). The patient was started on amoxicillin 7 days prior to the skin eruption for prophylaxis before removal of an intrauterine device.

Make the diagnosis
Donna Bilu Martin, MD

Mar 20th, 2019 - Ichthyosis vulgaris Ichthyoses describe a group of disorders of cornification in which the epidermis differentiates abnormally, leading to generalized scaling of the skin. Ichthyosis is derived from the Greek word for fish, “ichthys.

A 13-month-old, healthy black male presented with a 6-month history of dry, scaly skin on the body
Donna Bilu Martin, MD

Mar 20th, 2019 - Ichthyosis vulgaris Ichthyoses describe a group of disorders of cornification in which the epidermis differentiates abnormally, leading to generalized scaling of the skin. Ichthyosis is derived from the Greek word for fish, “ichthys.

Coalescing Hyperkeratotic Plaques and Papules
Joanna Jaros, BA, Artem M. Sergeyenko, MD et. al.

Nov 26th, 2018 - The Diagnosis: X-Linked Ichthyosis Immunohistochemical staining of a punch biopsy specimen from the left foot with cytokeratin markers AE1/3, 5/6, and 19 showed normal positive uptake. Further workup was recommended, and the patient was referred to genetics for an ichthyosis gene panel.

Study identifies potential biomarkers for an increased risk of SCARs-related mortality
Bianca Nogrady

Nov 21st, 2018 - Researchers have identified biomarkers that might eventually be used to flag cancer patients with severe cutaneous adverse reactions (SCARs) at an increased risk of mortality. In a retrospective study, elevated elafin, interleukin (IL)-6, and tumor necrosis factor (TNF)–alpha levels were significantly associated with a greater risk of all-cause mortality among hospitalized cancer patients who d.

Screening for Depression in Rosacea Patients
Hossein Alinia, MD, Leah A. Cardwell, MD et. al.

Jul 9th, 2018 - Rosacea is a chronic skin condition that can be classified into 4 subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular. Erythematotelangiectatic rosacea is characterized by redness of the face and excessive blushing.

Ethnicity Matters in Allopurinol Reactions

Apr 17th, 2018 - Action Points Note that this study using administrative data identified multiple risk factors (including non-white race and female sex) associated with allopurinol-induced hypersensitivity reactions. Be aware that this was based on administrative coding of the reactions, which may lead to some bias in the results. Certain minorities are at greatly increased risk of potentially lethal severe cut...

Pediatric Dermatology Consult - March 2018
Pediatric News; Allison Han, Lawrence F. Eichenfield, MD

Apr 3rd, 2018 - Rosacea is a chronic inflammatory skin disorder characterized by flushing, telangiectasia, erythema, papules, and pustules, most classically of the central face. Fair-skinned individuals and women are more commonly affected than are men, with age of onset typically around 30 years and older.

Fast Five Quiz: How Much Do You Know About Erythema Multiforme?

Feb 14th, 2018 - Erythema multiforme is an acute, self-limited, and sometimes recurring skin condition that is considered to be a type IV hypersensitivity reaction associated with certain infections, medications, and other various triggers. Severity variants are (1) erythema multiforme consisting of erythema minor and major and (2) Stevens-Johnson syndrome and toxic epidermal necrolysis. Erythema multiforme min...

Sjögren-Larsson Syndrome: Definitive Diagnosis on Magnetic Resonance Spectroscopy

Dec 4th, 2017 - Comment Presentation The characteristic clinical features of SLS begin to develop during the intranatal period and infancy. 1,6 Pathologic skin involvement can be detected as early as week 23 of gestation.

Don’t overlook all options for ocular rosacea
Heidi Splete

Nov 2nd, 2017 - Managing ocular rosacea often includes a combination of oral and topical treatments, and some patients find relief with natural strategies such as warm compresses and eyelid massage, Julie C. Harper, MD, said at the Skin Disease Education Foundation’s annual Las Vegas Dermatology Seminar.

New genetic causes of ichthyoses likely to emerge
Doug Brunk

Aug 11th, 2017 - CHICAGO– The way Keith Choate, MD, PhD, sees it, he and other clinicians are only beginning to scratch the surface on their understanding of the genetic causes of ichthyosis and ichthyosis syndromes. “Despite the fact that we now understand that there are about 21,000 genes in the genome, we have very superficial understanding and functions known for only about 4,000 genes,” Dr.

Stevens-Johnson Syndrome Secondary to Isolated Albuterol Use

Aug 9th, 2017 - After hospital admission, the patient’s mucosal desquamation progressively improved. By day 3, he required minimal supplemental oxygen with resolution of bowel symptoms and improved mucosal and skin findings.

Care of infants with ichthyosis requires ‘all hands on deck’
Doug Brunk

Aug 2nd, 2017 - CHICAGO – The neonatal period and early infancy are especially critical for patients with ichthyosis, because compromised barrier function increases risk for morbidity and mortality. “There are minimal data presently to guide management of patients with ichthyosis, making it a time of uncertainty,” Brittany Craiglow, MD, said at the World Congress of Pediatric Dermatology.

It's Not Appealing, But It Is A-Peeling

Jul 27th, 2017 - DISCUSSION Ichthyosis vulgaris (IV) is one of a family of disorders that cause a breakdown of normal filamentous structures (filaggrin) that hold the layers of skin together. This breakdown can lead to excessive water loss, as well as vulnerability of skin to penetration by allergens and other noxious substances.

Supportive care alone linked to worse outcomes in mucocutaneous reactions
Doug Brunk

Jul 19th, 2017 - CHICAGO – Pediatric patients with Stevens-Johnson syndrome and toxic epidermal necrolysis who received purely supportive care and surgical debridement had poorer outcomes, compared with other treatment modalities, a systematic review suggested. Although rare in the pediatric population – with an incidence of approximately 1 case in 2 million – Stevens-Johnson syndrome (SJS) and toxic epidermal.