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About 1,221 results

ALLMedicine™ Aniridia Center

Research & Reviews  609 results

Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Tra...
https://doi.org/10.1097/ICO.0000000000002729
Cornea Behaegel J, Tassignon MJ et. al.

Apr 30th, 2021 - To assess the efficacy and safety of human leukocyte antigen-matched allogeneic cultivated limbal epithelial stem cell grafts in the treatment of aniridia-associated keratopathy (AAK). Six eyes of 6 patients with severe AAK received an allogeneic ...

Maternal finger-prick allogenic blood for persistent corneal epithelial defects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042995
BMJ Case Reports; Pujari R, Deshmukh R et. al.

Apr 10th, 2021 - This is a case of a 17-year-old patient with aniridia-related keratopathy and persistent epithelial defect (PED) treated successfully using maternal finger-prick blood (FPB). Maternal allogenic FPB treatment was initiated to the patient who was no...

Activation of cryptic donor splice sites by non-coding and coding PAX6 variants contrib...
https://doi.org/10.1136/jmedgenet-2020-106932
Journal of Medical Genetics; Tarilonte M, Ramos P et. al.

Mar 30th, 2021 - The paired-domain transcription factor paired box gene 6 (PAX6) causes a wide spectrum of ocular developmental anomalies, including congenital aniridia, Peters anomaly and microphthalmia. Here, we aimed to functionally assess the involvement of se...

Reper intraocular lens with artificial iris: implantation techniques and outcomes.
https://doi.org/10.1177/11206721211005693
European Journal of Ophthalmology; Frisina R, De Biasi CS et. al.

Mar 29th, 2021 - The authors describe the surgical techniques to implant a novel intraocular lens with artificial iris (Reper) in patients affected by traumatic aphakia and aniridia. Two surgical approaches are proposed: implantation by suture-loaded cartridge and...

Outcomes of Glaucoma Drainage Device Implantation and Trabeculectomy With Mitomycin C i...
https://doi.org/10.1016/j.ajo.2021.03.008
American Journal of Ophthalmology; Durai I, Pallamparthy S et. al.

Mar 19th, 2021 - To compare the outcomes of Aurolab aqueous drainage implant (AADI; Aurolab) placement and trabeculectomy with mitomycin C (MMC) in patients with glaucoma secondary to aniridia. Retrospective comparative interventional case series. This study inclu...

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Clinicaltrials.gov  611 results

Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Tra...
https://doi.org/10.1097/ICO.0000000000002729
Cornea Behaegel J, Tassignon MJ et. al.

Apr 30th, 2021 - To assess the efficacy and safety of human leukocyte antigen-matched allogeneic cultivated limbal epithelial stem cell grafts in the treatment of aniridia-associated keratopathy (AAK). Six eyes of 6 patients with severe AAK received an allogeneic ...

Maternal finger-prick allogenic blood for persistent corneal epithelial defects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8042995
BMJ Case Reports; Pujari R, Deshmukh R et. al.

Apr 10th, 2021 - This is a case of a 17-year-old patient with aniridia-related keratopathy and persistent epithelial defect (PED) treated successfully using maternal finger-prick blood (FPB). Maternal allogenic FPB treatment was initiated to the patient who was no...

Activation of cryptic donor splice sites by non-coding and coding PAX6 variants contrib...
https://doi.org/10.1136/jmedgenet-2020-106932
Journal of Medical Genetics; Tarilonte M, Ramos P et. al.

Mar 30th, 2021 - The paired-domain transcription factor paired box gene 6 (PAX6) causes a wide spectrum of ocular developmental anomalies, including congenital aniridia, Peters anomaly and microphthalmia. Here, we aimed to functionally assess the involvement of se...

Reper intraocular lens with artificial iris: implantation techniques and outcomes.
https://doi.org/10.1177/11206721211005693
European Journal of Ophthalmology; Frisina R, De Biasi CS et. al.

Mar 29th, 2021 - The authors describe the surgical techniques to implant a novel intraocular lens with artificial iris (Reper) in patients affected by traumatic aphakia and aniridia. Two surgical approaches are proposed: implantation by suture-loaded cartridge and...

Outcomes of Glaucoma Drainage Device Implantation and Trabeculectomy With Mitomycin C i...
https://doi.org/10.1016/j.ajo.2021.03.008
American Journal of Ophthalmology; Durai I, Pallamparthy S et. al.

Mar 19th, 2021 - To compare the outcomes of Aurolab aqueous drainage implant (AADI; Aurolab) placement and trabeculectomy with mitomycin C (MMC) in patients with glaucoma secondary to aniridia. Retrospective comparative interventional case series. This study inclu...

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News  1 results

FDA OKs First Prosthetic Iris
https://www.medpagetoday.com/ophthalmology/generalophthalmology/73181

May 30th, 2018 - The FDA approved the first stand-alone prosthetic iris on Wednesday for adults and children with aniridia, a rare congenital condition, or other damage to the eye. Made of thin and foldable medical-grade silicone, CustomFlex Artificial Iris is ind...

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