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About 563 results

ALLMedicine™ Aniridia Center

Research & Reviews  222 results

New mutation in WT1 gene in a boy with an incomplete form of Denys-Drash syndrome: A CA...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133155
Medicine Akramov NR, Shavaliev RF et. al.

Jun 10th, 2021 - Pediatric patients with WTl-associated syndromes (including Wilms' tumor-aniridia syndrome and Denys-Drash syndrome), Perlman syndrome, mosaic aneuploidy, and Fanconi anemia with a biallelic breast cancer type 2 susceptibility protein mutation hav...

Dysfunction of the limbal epithelial stem cell niche in aniridia-associated keratopathy.
https://doi.org/10.1016/j.jtos.2021.06.002
The Ocular Surface; Schlötzer-Schrehardt U, Latta L et. al.

Jun 9th, 2021 - Abnormalities in the limbal niche microenvironment have been suggested to be causally involved in aniridia-associated keratopathy (AAK), but histological analyses on the limbal structure and composition in AAK are lacking. Here, we investigated mo...

A novel variant in PAX6 as the cause of aniridia in a Chinese family.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136215
BMC Ophthalmology; Jin X, Liu W et. al.

May 22nd, 2021 - Aniridia is a kind of congenital human pan-ocular anomaly, which is related to PAX6 commonly. The ophthalmic examinations including visual acuity, slit lamp and fundoscopy examination were performed in a Chinese aniridia pedigree. The targeted nex...

Outcomes of Human Leukocyte Antigen-Matched Allogeneic Cultivated Limbal Epithelial Tra...
https://doi.org/10.1097/ICO.0000000000002729
Cornea Behaegel J, Tassignon MJ et. al.

May 1st, 2021 - To assess the efficacy and safety of human leukocyte antigen-matched allogeneic cultivated limbal epithelial stem cell grafts in the treatment of aniridia-associated keratopathy (AAK). Six eyes of 6 patients with severe AAK received an allogeneic ...

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Clinicaltrials.gov  2 results

Genetics of Wilms' Tumor and/or the Associated Conditions of Aniridia, Hemihypertrophy, and Genitourinary Anomalies
https://clinicaltrials.gov/ct2/show/NCT00503893

Jan 27th, 2020 - If you choose to take part in this study, blood (about 10 teaspoons) will be drawn for genetic testing. The blood may be drawn more than 1 time, depending on how much blood is drawn at the first visit, and if you are available for more blood draws...

Clinical Evaluation of Morcher Artificial Iris Diaphragms
https://clinicaltrials.gov/ct2/show/NCT00812708

Jun 28th, 2018 - Aniridia is a condition in which the iris, the colored portion of the eye, is either partially or completely absent. The iris is responsible for regulating the amount of light entering the eye by adjusting the size of the pupil. Aniridia can eithe...

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News  1 results

FDA OKs First Prosthetic Iris
https://www.medpagetoday.com/ophthalmology/generalophthalmology/73181

May 30th, 2018 - The FDA approved the first stand-alone prosthetic iris on Wednesday for adults and children with aniridia, a rare congenital condition, or other damage to the eye. Made of thin and foldable medical-grade silicone, CustomFlex Artificial Iris is ind...

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