About 360 results

ALLMedicine™ Juvenile Xanthogranuloma Center

Research & Reviews  138 results

What is the Role of Different Macrophage Subsets in the Evolution of Juvenile Xanthogra...
Applied Immunohistochemistry & Molecular Morphology : AIMM; Wegher LSM, Kazmarek LM et. al.

Apr 19th, 2022 - There are several activated forms of macrophages: 2 main groups are designated M1 and M2. While M1 macrophages have proinflammatory, bactericidal, and phagocytic functions and are the dominant phenotype observed in the early stages of inflammation...

Giant Juvenile Xanthogranuloma of face in an adult: A rare complexity.
Journal of Stomatology, Oral and Maxillofacial Surgery; Richardson S, Banerjee P et. al.

Apr 9th, 2022 - Juvenile xanthogranuloma, a form of non-Langerhans cell histiocytosis can be defined as the proliferation of cells with macrophage like characteristics. It has been described as a benign, asymptomatic and common self-healing disorder of non-Langer...

Juvenile and adult xanthogranuloma: A 30-year single-center experience and review of th...
Annals of Diagnostic Pathology; Salari B, Dehner LP

Apr 5th, 2022 - Juvenile xanthogranuloma (JXG) is the most common type of non-Langerhans cell histiocytosis whose cell of origin, etiology and pathogenesis are not fully understood. We aimed to provide an update on histopathologic and immunophenotypic profile of ...

Juvenile Xanthogranuloma: A Comparative Immunohistochemical Study of Factor XIIIa, CD11...
The American Journal of Dermatopathology; Salari B, Dehner LP

Mar 23rd, 2022 - Juvenile xanthogranuloma is a group C and L non-Langerhans cell histiocytosis, and its cell of origin is still debatable. The expression of CD11c, a more recently described macrophage marker, and CD4 have not been studied comprehensively. This stu...

Intralesional glucocorticoid treatment of an isolated intracranial juvenile xanthogranu...
https://doi.org/10.1007/s00381-022-05500-z 10.1111/j.1440-1789.2012.01323.x 10.1007/s12519-009-0015-4 10.1016/0190-9622(93)70259-v 10.1097/00000478-200305000-00003 10.1016/s1085-5629(99)80017-0 10.5858/arpa.2015-0199-RA
Child's Nervous System : ChNS : Official Journal of the I... Damodharan S, Diamond C et. al.

Mar 20th, 2022 - Juvenile xanthogranuloma is a type of non-Langerhans cell histiocytic process that appears primarily in children and is described as a benign lesion. Although they typically present as a cutaneous lesion, it can also present in other areas includi...

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Clinicaltrials.gov  2 results

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Sep 2nd, 2021 - Histiocytic disorders are diseases caused by misfunctioning or buildup of particular immune cells called histiocytes. Many histiocytic disorders (LCH, juvenile xanthogranuloma (JXG), Erdheim-Chester disease (ECD), and Rosai-Dorfman Disease (RDD)) ...

International Rare Histiocytic Disorders Registry (IRHDR)

Mar 9th, 2021 - Histiocytoses are rare diseases caused by an excess of cells called Histiocytes, which can infiltrate the skin, bones, lungs, liver, spleen and the central nervous system. These disorders can range from localized involvement that resolves spontane...

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News  4 results

Child with yellow nodule
MDedge Family Medicine;

Feb 11th, 2021 - The characteristic orange-yellow color is the tip-off to the diagnosis of juvenile xanthogranuloma (JXG). It manifests as asymptomatic solitary or scattered papules or nodules, congenitally, or most commonly during the first year of life.

Yellow-Brown Ulcerated Papule in a Newborn
Tia M. Pyle, MD, Warren R. Heymann, MD

Nov 11th, 2019 - The Diagnosis: Congenital Self-healing Reticulohistiocytosis Biopsy of a representative lesion from this patient was consistent with congenital self-healing reticulohistiocytosis, as shown in the Figure. Characteristic Langerhans cells were presen.

Rubbery Nodule on the Face of an Infant
John R. Chancellor, MD, MS, Laura A. Gonzalez-Krellwitz, MD et. al.

Aug 6th, 2019 - The Diagnosis: Juvenile Xanthogranuloma Juvenile xanthogranuloma (JXG) was first described in 1905 by Adamson1 as solitary or multiple plaquiform or nodular lesions that are yellow to yellowish brown. In 1954, Helwig and Hackney2 coined the term j.

Pediatric Dermatology Consult - April 2017

Apr 21st, 2017 - BY JEREMY UDKOFF AND CATALINA MATIZ, MD Juvenile xanthogranuloma (JXG), a non–Langerhans cell histiocytosis, is a common pediatric tumor that most commonly presents either at birth, in infants, or in young children – with the majority of cases occ.

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