ALLMedicine™ Xeroderma Pigmentosum Center
Research & Reviews 394 results
https://doi.org/10.1177/11206721221100903
European Journal of Ophthalmology; Rajagopal R, Srinivasan B et. al.
May 11th, 2022 - To report a rare presentation of bilateral, coexisting ocular surface disease in a case of Xeroderma pigmentosum and its successful management. Case report. A 21-year-old male with Xeroderma pigmentosum presented with bilateral ocular surface squa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096195
Cell Transplantation; Dai W, Wu A et. al.
May 11th, 2022 - Glioblastoma is the most frequent, as well as aggressive kind of high-grade malignant glioma. Chemoresistance is posing a significant clinical barrier to the efficacy of temozolomide-based glioblastoma treatment. By suppressing xeroderma pigmentos...
https://doi.org/10.1111/pde.15007
Pediatric Dermatology; Peterson MY, Hanson B et. al.
May 7th, 2022 - Two siblings presented with sun sensitivity and progressive dyspigmentation. A diagnosis of xeroderma pigmentosum was initially favored due to XPC mutations, although variants were not clearly diagnostic. However, new moderate neutropenia and homo...
https://doi.org/10.1136/jmedgenet-2021-108323
Journal of Medical Genetics; Sarkany R, Norton S et. al.
Apr 9th, 2022 - For patients with xeroderma pigmentosum (XP), the main means of preventing skin and eye cancers is extreme protection against ultraviolet radiation (UVR), particularly for the face. We have recently developed a methodology for objectively measurin...
https://www.ncbi.nlm.nih.gov/books/n/gene/xp/
Mar 24th, 2022 - Xeroderma pigmentosum (XP) is characterized by:
Drugs 1 results see all →
Clinicaltrials.gov 6 results
https://clinicaltrials.gov/ct2/show/NCT03445052
Jul 22nd, 2020 - Xeroderma Pigmentosum (XP) is a rare autosomal recessive inherited condition caused by defective Nucleotide Excision Repair. Patients may develop skin cancers from childhood onwards, ocular damage, and neurological deterioration. The clinical mana...
https://clinicaltrials.gov/ct2/show/NCT00002811
Nov 6th, 2013 - OBJECTIVES: I. Compare the safety and efficacy of T4N5 liposome lotion vs. a placebo lotion in reducing the incidence of actinic keratoses and protecting against other ultraviolet skin damage in patients with xeroderma pigmentosum. OUTLINE: Random...
https://clinicaltrials.gov/ct2/show/NCT00086996
Oct 11th, 2013 - OBJECTIVES: Primary Determine the pathologic complete response probability in patients with stage II or III adenocarcinoma of the esophagus or gastroesophageal junction treated with neoadjuvant oxaliplatin, fluorouracil, and radiotherapy followed ...
https://clinicaltrials.gov/ct2/show/NCT00025012
Jun 19th, 2013 - OBJECTIVES: I. Determine the lowest effective dose of oral isotretinoin for long-term therapy that is capable of reducing the rate of formation of new skin cancers in patients with xeroderma pigmentosum or nevoid basal cell carcinoma syndrome. II....
https://clinicaltrials.gov/ct2/show/NCT00797238
Jul 15th, 2010 - Patients with clinical stage IIIA N2 non-small cell lung cancer (NSCLC) have a 5-year survival rate of 10% to 15%, much worse than those of earlier stages of disease. The use of pre-operative (neo-adjuvant) chemotherapy has been shown to be benefi...
News 11 results
https://reference.medscape.com/viewarticle/936083_2
Aug 21st, 2020 - Primary risk factors and clinical warning signs for melanoma include: Changing mole (most important clinical warning sign) Presence of xeroderma pigmentosum or familial atypical mole melanoma syndrome Clinical atypical/dysplastic nevi in familial ...
https://www.medscape.com/viewarticle/923186
Dec 28th, 2019 - Simon Stevens, head of NHS England becomes a Sir, leading this year's healthcare field in the 2020 New Year Honours List. The recipients in healthcare are alongside stars of sport, entertainment, public service, politics, charity work, and "the ou...
https://www.mdedge.com/pediatrics/article/207921/pediatrics/expert-spotlights-telltale-clinical-signs-xeroderma-pigmentosum?channel=39313
Doug Brunk
Sep 10th, 2019 - AUSTIN, TEX. – If a child presents with acute photosensitivity at a young age, onset of freckling before the age of 2 years, and severe sun damage of the lips and eyes, think xeroderma pigmentosum (XP), a rare autosomal recessive disorder.
https://www.mdedge.com/clinicianreviews/article/150902/rare-diseases/small-kansas-town-turns-night-day-boy-rare-disease
Nov 1st, 2017 - A new documentary video developed by NORD shows how a small community in Kansas came together to support an 11-year-old boy who has a rare disease that makes it necessary for him to avoid sunlight. Peyton Madden has xeroderma pigmentosum (XP), a r.
https://www.mdedge.com/dermatology/article/80780/nonmelanoma-skin-cancer/solitary-nodular-lesion-scalp
Sotonye Imadojemu, MD, Mbe, Douglas J. Pugliese, MD, MPH et. al.
Mar 4th, 2014 - The Diagnosis: Pilomatricoma Pilomatricoma, first described by Malherbe and Chenantais1 in 1880, is a benign appendageal tumor derived from hair follicle matrix cells. It classically manifests as a solitary, asymptomatic, firm dermal nodule with a.