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About 2,213 results

ALLMedicine™ Optic Atrophy Center

Research & Reviews  821 results

Compressive Optic Neuropathy
https://emedicine.medscape.com/article/1217005-overview

Jan 23rd, 2023 - Background Compressive optic neuropathy (CON) is caused by injury to the optic nerve by an extrinsic lesion. [1] The primary function of the optic nerve is to transmit visual information from the retina to the brain. The optic nerve contains the a...

Compressive Optic Neuropathy
http://emedicine.medscape.com/article/1217005-overview

Jan 23rd, 2023 - Background Compressive optic neuropathy (CON) is caused by injury to the optic nerve by an extrinsic lesion. [1] The primary function of the optic nerve is to transmit visual information from the retina to the brain. The optic nerve contains the a...

Compressive Optic Neuropathy
https://emedicine.medscape.com/article/1217005-print

Jan 23rd, 2023 - Background Compressive optic neuropathy (CON) is caused by injury to the optic nerve by an extrinsic lesion.[1] The primary function of the optic nerve is to transmit visual information from the retina to the brain. The optic nerve contains the ax...

OPA1 Dominant Optic Atrophy: Diagnostic Approach in the Pediatric Population.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9857649
Current Issues in Molecular Biology; Arruti N, Rodríguez-Solana P et. al.

Jan 21st, 2023 - A clinical and genetic study was conducted with pediatric patients and their relatives with optic atrophy 1 (OPA1) mutations to establish whether there is a genotype-phenotype correlation among the variants detected within and between families. El...

Mitochondrial Membrane Protein Neurodegeneration (MPAN)
https://clinicaltrials.gov/ct2/show/NCT05678790

Jan 10th, 2023 - Neurodegeneration with brain iron accumulation (NBIA) comprises a heterogeneous group of disorders with accumulation of iron in the brain, mostly basal ganglia. Mutations within C19orf12 have recently been identified in patients with NBIA. This C1...

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Drugs  19 results see all →

Clinicaltrials.gov  25 results

Mitochondrial Membrane Protein Neurodegeneration (MPAN)
https://clinicaltrials.gov/ct2/show/NCT05678790

Jan 10th, 2023 - Neurodegeneration with brain iron accumulation (NBIA) comprises a heterogeneous group of disorders with accumulation of iron in the brain, mostly basal ganglia. Mutations within C19orf12 have recently been identified in patients with NBIA. This C1...

Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1
https://clinicaltrials.gov/ct2/show/NCT05659368

Dec 21st, 2022 - Wolfram syndrome (WFS:OMIM 222300) is a group of inherited disorders that usually appear in childhood and cause diabetes, optic atrophy leading to loss of vision, deafness and often diabetes insipidus. Wolfram syndrome affected no more than 0.2 in...

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome
https://clinicaltrials.gov/ct2/show/NCT04940572

Dec 19th, 2022 - Open label, phase II study non randomized single group assignment of 20 evaluable patients 13 years and older, over 37,5 kg body-weight, with sensorineural hearing loss of at least 20 dB at 8 kHz in high frequency average (HFA), AND with documente...

Development of a Cortical Visual Neuroprosthesis for the Blind
https://clinicaltrials.gov/ct2/show/NCT02983370

Dec 7th, 2022 - Visual impairment is one of the ten most prevalent disabilities and poses extraordinary challenges to individuals in our society, which is heavily dependent on sight. Drug development and genetic engineering have had only marginal success as possi...

Stem Cell Ophthalmology Treatment Study II
https://clinicaltrials.gov/ct2/show/NCT03011541

Nov 28th, 2022 - Eyes with loss of vision from retinal or optic nerve conditions generally considered irreversible will be treated with a combination of injections of autologous bone marrow derived stem cells isolated from the bone marrow using standard medical an...

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News  17 results

Clinical Presentation of Subacute Combined Degeneration in a Patient With Chronic B12 Deficiency
https://www.mdedge.com/fedprac/article/252920/neurology/clinical-presentation-subacute-combined-degeneration-patient
Nathan Kostick, Evan Chen et. al.

Mar 21st, 2022 - Subacute combined degeneration (SCD) is an acquired neurologic complication of vitamin B12 (cobalamin) or, rarely, vitamin B9 (folate) deficiency. SCD is characterized by progressive demyelination of the dorsal and lateral spinal cord, resulting i.

Cachexia Common in Lupus
https://www.medpagetoday.com/rheumatology/lupus/87893

Aug 4th, 2020 - Cachexia is an underappreciated complication of systemic lupus erythematosus, researchers reported. A total of 56.3% of patients developed the involuntary weight loss accompanied by loss of homeostatic control of protein and energy balance within ...

A 10-Year-Old Boy With Fainting Spells and Seizure Activity
https://reference.medscape.com/viewarticle/884107_6

Sep 25th, 2019 - Question 1 of 2 Which of the following conditions is not associated with congenital LQTS? Your Peers Chose: Congenital sensorineural hearing loss 0% Congenital optic atrophy 0% Syncopal attacks 0% Seizures 0% Sudden cardiac death 0% Important clue...

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Patient Education  3 results see all →