ALLMedicine™ Optic Atrophy Center
Research & Reviews 676 results
https://doi.org/10.1007/s10792-022-02350-1 10.1016/j.ncl.2010.03.005 10.1111/j.1742-1241.2005.00541.x 10.3126/jucms.v3i2.14287 10.4274/tjo.galenos.2020.76301 10.3109/09286589609080118 10.1177/112067210401400613 10.26719/2018.24.2.161 10.1111/j.1755-3768.1992.tb04876.x 10.4103/0366-6999.241795 10.1097/WNO.0000000000000491 10.1001/archopht.1997.01100160573008 10.1097/WNO.0000000000000923 10.1007/s10792-020-01448-8 10.1016/j.ophtha.2016.05.008 10.4103/0301-4738.121131 10.1001/archneur.65.6.727 10.3126/nepjoph.v9i1.17533 10.1177/1352458517734070 10.1007/s10792-017-0491-9 10.1038/eye.2009.79 10.1016/j.jaapos.2012.04.009 10.1097/SCS.0b013e31824cd4a7 10.1097/00006534-200106000-00003 10.1136/jmg.2007.054270 10.1111/aos.12515
International Ophthalmology; Kılıçarslan O, Yılmaz Çebi A et. al.
May 14th, 2022 - Optic atrophy is an end-stage pathology of optic nerve diseases that is characterized by optic nerve pallor and vision loss. Because of its sight-threatening effects, understanding its epidemiology and etiology is crucial. In this study, we aimed ...
https://doi.org/10.1038/s41431-022-01102-0 10.1016/j.ophtha.2009.12.038 10.1136/jmg.2007.054270 10.1093/brain/awq007 10.1038/s41431-018-0235-y 10.1093/brain/awu165 10.1136/jmedgenet-2015-103361 10.1093/hmg/ddm079 10.1093/brain/awm005 10.1371/journal.pone.0253987 10.3109/13816810.2015.1066829 10.1186/s12881-017-0383-x 10.1002/acn3.323 10.1089/1066527041410418 10.1093/nar/gkp215 10.1093/nar/gkl535 10.1016/0022-2836(91)90380-O 10.1038/nprot.2015.053 10.1038/nprot.2006.273 10.1016/j.omtn.2021.08.015 10.1186/s13023-018-0972-6 10.1093/brain/awm298 10.1007/s13353-018-0444-7 10.1167/iovs.14-16288 10.1167/iovs.61.6.42 10.1038/nsmb.1550 10.1038/ncb0805-766 10.1038/nrn2417 10.15252/embj.201488349 10.1091/mbc.e09-03-0252 10.1038/s41598-016-0028-x 10.1007/s00018-019-03024-5 10.1186/1750-1326-8-32 10.1002/bies.201400188
European Journal of Human Genetics : EJHG; Harvey JP, Yu-Wai-Man P et. al.
May 10th, 2022 - Autosomal dominant optic atrophy (DOA) is an inherited optic neuropathy that results in progressive, bilateral visual acuity loss and field defects. OPA1 is the causative gene in around 60% of cases of DOA. The majority of patients have a pure ocu...
https://doi.org/10.1016/j.jns.2022.120271
Journal of the Neurological Sciences; Donaldson L, Jhaveri A et. al.
May 8th, 2022 - Idiopathic intracranial hypertension (IIH) is a condition that most often occurs in women of reproductive age with elevated body mass index (BMI) (typical patients). Individuals outside of this demographic group (atypical patients) may have a diff...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078049
Investigative Ophthalmology & Visual Science; Chang YH, Kang EY et. al.
May 5th, 2022 - To compare the manifestations of photoreceptors (PRs) in three hereditary optic neuropathies affected by primary mitochondrial dysfunction and discuss whether the retinal ganglion cells (RGCs) or the PRs are preferentially affected. A retrospectiv...
https://doi.org/10.1016/j.jns.2022.120267
Journal of the Neurological Sciences; Kabanovski A, Donaldson L et. al.
Apr 27th, 2022 - Wolfram Syndrome (WS) is a rare progressive hereditary neurodegenerative disease with hallmark features of diabetes mellitus, optic atrophy, and hearing loss. Its other clinical manifestations may include diabetes insipidus, urological, neurologic...
Drugs 12 results see all →
Clinicaltrials.gov 7 results
https://clinicaltrials.gov/ct2/show/NCT04273165
Mar 31st, 2022 - Friedreich ataxia is a rare progressive neurodegenerative disease presenting in childhood or late adolescence for which no treatment is currently available. The disease is caused by the defective synthesis of Frataxin, a mitochondrial protein synt...
https://clinicaltrials.gov/ct2/show/NCT04594590
Mar 8th, 2022 - The number of mitochondria in the cell is dynamic and is regulated by two opposite processes, namely fission and fusion. Proteins in both the inner mitochondrial membrane (IMM) and the outer mitochondrial membrane (OMM) are involved in mediating t...
https://clinicaltrials.gov/ct2/show/NCT02983370
Oct 6th, 2021 - Visual impairment is one of the ten most prevalent disabilities and poses extraordinary challenges to individuals in our society, which is heavily dependent on sight. Drug development and genetic engineering have had only marginal success as possi...
https://clinicaltrials.gov/ct2/show/NCT03857607
Feb 11th, 2021 - Alternating hemiplegia of childhood (AHC) is a rare very disabling neurodevelopmental syndrome caused by mutations in the gene ATP1A3. AHC is characterized by paroxysmal events including attacks of hemiplegia (weakness), dystonia (painful stiffeni...
https://clinicaltrials.gov/ct2/show/NCT01920867
Oct 23rd, 2019 - Eyes with loss of vision from retinal or optic nerve conditions generally considered irreversible will be treated with a combination of injections of autologous bone marrow derived stem cells isolated from the bone marrow using standard medical an...
News 14 results
https://www.mdedge.com/fedprac/article/252920/neurology/clinical-presentation-subacute-combined-degeneration-patient
Nathan Kostick, Evan Chen et. al.
Mar 21st, 2022 - Subacute combined degeneration (SCD) is an acquired neurologic complication of vitamin B12 (cobalamin) or, rarely, vitamin B9 (folate) deficiency. SCD is characterized by progressive demyelination of the dorsal and lateral spinal cord, resulting i.
https://www.medpagetoday.com/rheumatology/lupus/87893
Aug 4th, 2020 - Cachexia is an underappreciated complication of systemic lupus erythematosus, researchers reported. A total of 56.3% of patients developed the involuntary weight loss accompanied by loss of homeostatic control of protein and energy balance within ...
https://reference.medscape.com/viewarticle/884107_6
Sep 25th, 2019 - Question 1 of 2 Which of the following conditions is not associated with congenital LQTS? Your Peers Chose: Congenital sensorineural hearing loss 0% Congenital optic atrophy 0% Syncopal attacks 0% Seizures 0% Sudden cardiac death 0% Important clue...
https://www.mdedge.com/dermatology/article/195549/mixed-topics/recurrence-elevated-intracranial-pressure-following?channel=52
Ashwini T. Kini, MD, Niloufar Rohani, BBA et. al.
Mar 4th, 2019 - To the Editor: In 1995, one of the authors (A. G.
https://www.medscape.com/viewarticle/894595_2
Apr 3rd, 2018 - Case Diagnosis Funduscopy showed a marked asymmetry in the optic disc cup size, with focal tissue loss inferiorly of the right optic disc. There was no optic disc pallor. The cupping of the optic disc, in the absence of optic disc pallor, was sugg...