ALLMedicine™ Papilledema Center

Mar 18th, 2023 - We reviewed the medical case report literature to determine the proportion of cases of idiopathic intracranial hypertension (IIH) that were either inappropriately labelled as IIH or prematurely given this diagnosis. We searched OVID MEDLINE from 2...

Mar 11th, 2023 - To analyze the pattern of pediatric ophthalmology inpatient consults at a single children's hospital over 5 years. The records of all pediatric ophthalmology consults over a 5-year period were reviewed retrospectively. A total of 1,805 new pediatr...

Mar 11th, 2023 - A pediatric female with sickle cell disease (SCD) and neurofibromatosis type 1 was noted to have incidental papilledema, with subsequent workup showing an elevated opening pressure. She was diagnosed with intracranial hypertension and began treatm...

Mar 9th, 2023 - Practice Essentials Ependymomas are glial tumors that derive from ependymal cells and can arise anywhere within the central nervous system. These tumors tend to present intracranially in children and spinally in adults.[1] Ependymomas are heteroge...

Mar 9th, 2023 - History The type of neurologic signs and symptoms that result from an astrocytoma depends foremost on the site and extent of tumor growth in the central nervous system (CNS). Onset of any of the following should alert the clinician to the presence...

Feb 1st, 2023 - The incidence of craniosynostosis is reported to be 1/2,000 births. Craniosynostosis is a birth defect that causes one or more sutures on a baby's head to close earlier than normal. The skull of an infant or young child is made up of bony plates t...

Dec 13th, 2022 - Idiopathic intracranial hypertension (IIH) is a rare disease of increasing incidence recently[1], owing to the rising curve of obesity and weight gain[2,3]. It is a disease of elevated intracranial pressure without known obvious aetiology. The rep...

Aug 22nd, 2022 - Craniosynostosis is defined as the premature fusion of one or more of the sutures normally separating the infant's skull bony plates, resulting in abnormal growth of the cranial vault and skull base, which may influence brain growth and developmen...

Jul 7th, 2022 - The main objective of our study will be to compare the treatment with bosentan to placebo for 8 weeks for recovery anatomical criteria (RFNL in OCT, optic atrophy) and functional (visual acuity, visual field). The primary endpoint will be the impr...

Jun 16th, 2022 - After signing the informed consent form, potential subjects will be assessed for eligibility, including eliciting medical and neurologic history, measurement of best-corrected visual acuity, visual field testing, ophthalmoscopy with optic disc ede...

Mar 20th, 2023 - Tofersen, an investigational antisense drug developed to treat amyotrophic lateral sclerosis (ALS) associated with a mutation in the SOD1 gene (SOD1-ALS), may have clinical benefit, FDA reviewers indicated in briefing documents ahead of an advisor...

Sep 21st, 2022 - Tofersen, an investigational antisense oligonucleotide developed to treat an inherited form of amyotrophic lateral sclerosis (ALS), changed biomarkers and curbed neurodegeneration but did not improve motor control and muscle strength at 6 months, ...

Apr 26th, 2021 - Among women with idiopathic intracranial hypertension (IIH) and a body mass index (BMI) of 35 or higher, bariatric surgery was a more effective means of reducing intracranial pressure and sustaining disease remission compared with a community weig...

Jul 12th, 2019 - Idiopathic intracranial hypertension (IIH) in women appears to be associated with an increased cardiovascular risk, new research shows. "This is a landmark study in that the possible long-term sequelae of idiopathic intracranial hypertension have ...

Jul 10th, 2019 - Discussion Idiopathic orbital inflammation is a benign inflammatory-mediated condition of the orbit without a known systemic or local etiology.[5] The condition is typically seen in middle-aged adults and affects women more than men.[5] Despite be...